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Numéro de catalogue: (PRSI91-931)

Fournisseur:  ProSci Inc.
Description:   CD27 antigen is also known as CD27L receptor, T-cell activation antigen CD27, Tumor necrosis factor receptor superfamily member 7, T14 and TNFRSF7. In humans, it is encoded by the CD27 gene. CD27 is a single-pass type I membrane protein with 3 TNFR-Cys repeats. It is a member of the TNF-receptor superfamily and is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. It plays a role in survival of activated T-cells and apoptosis through association with SIVA1.
UOM:  1 * 50 µG
Fournisseur:  AAT BIOQUEST
Description:   Flow cytometry combined with fluorescence staining is a powerful tool to analyze heterogeneous cell populations.
New Product
Numéro de catalogue: (PRSI48-861)

Fournisseur:  ProSci Inc.
Description:   Replication protein A (RPA) is a single-stranded DNA binding protein. Human RPA is a heterotrimeric protein containing subunits of 70, 32 and 14 kDa. This protein complex is highly conserved in eukaryotes and is essential in DNA replication, homologous recombination and nucleotide excision repair. RPA has been shown to be a target for DNA-dependent protein kinase (DNA-PK) ataxia telangiectasia-mutated gene (ATM) and a cyclin dependent protein kinase.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI91-815)

Fournisseur:  ProSci Inc.
Description:   CD320 antigen is also known as 8D6 antigen,FDC-signaling molecule 8D6,Transcobalamin receptor and 8D6A. It is a single-pass type I membrane protein and containing two LDL-receptor class A domains. CD320 has been recently discovered and reported as a follicular dendritic cell (FDC) protein. CD320 can augments the proliferation of plasma cells precursors generated by IL-10. CD320 also founctions a receptor for the cellular uptake of transcobalamin bound cobalamin. Defects in CD320 are the cause of methylmalonic aciduria type TCblR (MMATC) which is a metabolic disorder.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI91-744)

Fournisseur:  ProSci Inc.
Description:   CD160 antigen is a Lipid-anchor that exists as a disulfide-linked homomultimer. CD160 contains one Ig-like V-type domain. The human CD160 precursor is a cysteine-rich, glycosylphosphatidylinositol-anchored protein of 181 amino acids with a single Ig-like domain. It is weakly homologous to KIR2DL4. CD160 is expressed in the spleen, peripheral blood, and small intestine. Its expression is tightly associated with peripheral blood NK cells and CD8 T lymphocytes with cytolytic effector activity. CD160 is a receptor showing broad specificity for both classical and non-classical MHC class I molecules.
UOM:  1 * 50 µG
Numéro de catalogue: (ANTIA82566-100)

Fournisseur:  ANTIBODIES.COM
Description:   Goat polyclonal antibody to AGBL5 for ELISA and flow cytometry with samples derived from mouse.
UOM:  1 * 1 EA
New Product
Numéro de catalogue: (ANTIA285984-100)

Fournisseur:  ANTIBODIES.COM
Description:   Goat polyclonal antibody to Hornerin for ELISA, IF and Flow cytometry with samples derived from human.
UOM:  1 * 1 EA
New Product
Numéro de catalogue: (PRSI91-598)

Fournisseur:  ProSci Inc.
Description:   Macrophage colony-stimulating factor 1(M-csf)is a single-pass type I membrane protein . It is a hematopoietic growth factor that is involved in the proliferation, differentiation, and survival of monocytes, macrophages, and bone marrow progenitor cells. M-CSF affects macrophages and monocytes in several ways, including stimulating increased phagocytic and chemotactic activity, and increased tumour cell cytotoxicity. The role of M-CSF is not only restricted to the monocyte/macrophage cell lineage. By interacting with its membrane receptor, M-CSF also modulates the proliferation of earlier hematopoietic progenitors and influence numerous physiological processes involved in immunology, metabolism, fertility and pregnancy.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI91-933)

Fournisseur:  ProSci Inc.
Description:   CD320 antigen is also known as 8D6 antigen,FDC-signaling molecule 8D6,Transcobalamin receptor and 8D6A. It is a single-pass type I membrane protein and containing two LDL-receptor class A domains. CD320 has been recently discovered and reported as a follicular dendritic cell (FDC) protein. CD320 can augments the proliferation of plasma cells precursors generated by IL-10. CD320 also founctions a receptor for the cellular uptake of transcobalamin bound cobalamin. Defects in CD320 are the cause of methylmalonic aciduria type TCblR (MMATC) which is a metabolic disorder.
UOM:  1 * 50 µG
Fournisseur:  Binder
Description:   Temperature measurement of the specimen - with flexible Pt 100 sensor and digital specimen temperature display, Pour: Vacuum drying chambers, VD and VDL series
Numéro de catalogue: (PRSI92-595)

Fournisseur:  ProSci Inc.
Description:   Growth hormone receptor is a transmembrane receptor for growth hormone (GH). GH is a single-chain polypeptide that is mainly synthesised and released from the anterior pituitary gland and plays essential roles in growth, development and metabolism. GH exerts its physiological actions via GH binding to its receptor in its extracellular domain. Binding of growth hormone to the receptor leads to receptor dimerisation and the activation of an intra- and intercellular signal transduction pathway leading to growth. Growth hormone receptor has been shown to interact with SGTA, PTPN11, Janus kinase 2, Suppressor of cytokine signaling 1 and CISH.
UOM:  1 * 50 µG
Numéro de catalogue: (ANTIA286041-100)

Fournisseur:  ANTIBODIES.COM
Description:   Goat polyclonal antibody to POU4F2 for ELISA and Flow cytometry with samples derived from human.
UOM:  1 * 1 EA
New Product
Numéro de catalogue: (ANTIA83229-100)

Fournisseur:  ANTIBODIES.COM
Description:   Goat polyclonal antibody to LARP2 for ELISA, IF and flow cytometry with samples derived from human.
UOM:  1 * 1 EA
New Product
Numéro de catalogue: (ANTIA83073-100)

Fournisseur:  ANTIBODIES.COM
Description:   Goat polyclonal antibody to PLA2R1 for ELISA and flow cytometry with samples derived from human.
UOM:  1 * 1 EA
New Product
Numéro de catalogue: (BOSSBS-10994R-A350)

Fournisseur:  Bioss
Description:   Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act as a scaffold protein to aid the localization of DNA repair proteins to the site of damage. Found at the ends of chromosomes, suggesting a further role in the maintenance of telomeric stability and the prevention of chromosomal end fusion. Also involved in modulation of transcription. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX, thereby regulating DNA damage response mechanism. Phosphorylates DCLRE1C, c-Abl/ABL1, histone H1, HSPCA, c-jun/JUN, p53/TP53, PARP1, POU2F1, DHX9, SRF, XRCC1, XRCC1, XRCC4, XRCC5, XRCC6, WRN, c-myc/MYC and RFA2. Can phosphorylate C1D not only in the presence of linear DNA but also in the presence of supercoiled DNA. Ability to phosphorylate TP53/p53 in the presence of supercoiled DNA is dependent on C1D.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-10994R-CY3)

Fournisseur:  Bioss
Description:   Serine/threonine-protein kinase that acts as a molecular sensor for DNA damage. Involved in DNA nonhomologous end joining (NHEJ) required for double-strand break (DSB) repair and V(D)J recombination. Must be bound to DNA to express its catalytic properties. Promotes processing of hairpin DNA structures in V(D)J recombination by activation of the hairpin endonuclease artemis (DCLRE1C). The assembly of the DNA-PK complex at DNA ends is also required for the NHEJ ligation step. Required to protect and align broken ends of DNA. May also act as a scaffold protein to aid the localization of DNA repair proteins to the site of damage. Found at the ends of chromosomes, suggesting a further role in the maintenance of telomeric stability and the prevention of chromosomal end fusion. Also involved in modulation of transcription. Recognizes the substrate consensus sequence [ST]-Q. Phosphorylates 'Ser-139' of histone variant H2AX/H2AFX, thereby regulating DNA damage response mechanism. Phosphorylates DCLRE1C, c-Abl/ABL1, histone H1, HSPCA, c-jun/JUN, p53/TP53, PARP1, POU2F1, DHX9, SRF, XRCC1, XRCC1, XRCC4, XRCC5, XRCC6, WRN, c-myc/MYC and RFA2. Can phosphorylate C1D not only in the presence of linear DNA but also in the presence of supercoiled DNA. Ability to phosphorylate TP53/p53 in the presence of supercoiled DNA is dependent on C1D.
UOM:  1 * 100 µl
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