Masterflex+Single-use+Flow+Sensor
Fournisseur:
Mettler - Toledo
Description:
These conductivity probes with integrated temperature sensor (NTC 30 kΩ) are suitable for different sample types. They all provide automatic temperature compensation.
Numéro de catalogue:
(GENO786-422)
Fournisseur:
G-Biosciences
Description:
Acetate film with acrylic adhesive. This self-adhesive microplate sealing tape is suitable for sealing both 96-well and 384-well plates. The precut, pressure-senstive tape seals and reseals the surface of the plates during incubations to prevent evaporation and allow more vigorous mixing. The tape will reseal the plates 2 to 3 times.
UOM:
1 * 1 KIT
Numéro de catalogue:
(620-4908)
Fournisseur:
HAMILTON BONADUZ
Description:
Gel-Glass is a maintenance-free combination electrode for everyday applications.
UOM:
1 * 1 ST
Fournisseur:
Greisinger
Description:
HCl/pepsin cleaning solution, 100 ml, shelf life 12 months, GRL100
Numéro de catalogue:
(PRSI91-470)
Fournisseur:
ProSci Inc.
Description:
Ephrin Type-A Receptor 7 (EPHA7) is a single-pass type I membrane protein which belongs to the Eph family of transmembrane receptor tyrosine kinases. It contains two fibronectin type-III domains, one protein kinase domain and one SAM (sterile alpha motif) domain. EPHA7 is a receptor for members of the ephrin-A family. Eph receptors are largely expressed throughout the ectoderm, mesoderm, and endoderm of vertebrate embryos. EPHA7 functions as a repulsive guidance molecule during the targeting of retinal axons to the superior colliculus and of neocortical axons to the thalamus. EPHA7 is expressed at a substantial level in most human lung cancers. The high expression of EPHA7 protein may participate in the malignancy transformation, invasion progression and metastasis of primary hepatocellular carcinoma. EPHA7 may involve in smoking related lung carcinogenesis.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-524)
Fournisseur:
ProSci Inc.
Description:
C-Type Lectin Domain Family 10 Member A (CLEC10A) is a type II transmembrane C-type lectin that is expressed on immature myleloid dendritic cells and alternatively activated (tolerogenic) macrophages. CLEC10A/MGL binds and internalizes molecules with terminal nonsialylated GalNAc carbohydrates such as the Tn carcinoma antigen. CLEC10A/MGL also binds the GP envelope glycoprotein on Marburg and Ebola viruses and enhances viral entry and infectivity. It constitute a unique class of C-type lectins because of their specificity for galactose and its structural homologues. CLEC10A is thought to participate in the recognition of molecules from both altered self and pathogens due to its monosaccharide specificity for Gal and N-acetylgalactosamine (GalNAc). Human and rat carry a single gene for CLEC10A/MGL, while mouse has two closely related MGL1 and MGL2 genes.
UOM:
1 * 50 µG
Fournisseur:
FRISTADS KANSAS GROUP
Description:
T-shirt with short sleeves, manufatured from 100% pre-shrunk, ring spun cotton (single jersey). The models in colour grey melange are made of 85% cotton and 15% viscose.
Numéro de catalogue:
(PRSI91-294)
Fournisseur:
ProSci Inc.
Description:
SLAMF7 is a single-pass type I membrane protein and contains 1 Ig-like C2-type (immunoglobulin-like) domain. SLAMF7 is expressed in NK cells, activated B-cells, NK-cell line but not in promyelocytic, B-cell lines, or T-cell lines. Although the cytoplasmic domain of CS1 contains immunoreceptor tyrosine-based switch motifs (ITSM), which enables to recruite signaling lymphocyte activation molecule (SLAM)-associated protein (SAP/SH2D1A), it activates NK cells in the absence of a functional SAP. SLAMF7 positively regulated natural killer cell functions by a mechanism dependent on the adaptor EAT-2 but not the related adaptor SAP. However, in the absence of EAT-2, CRACC potently inhibited natural killer cell function. It was also inhibitory in T cells, which are typically devoid of EAT-2. Thus, SLAMF7 can exert activating or inhibitory influences on cells of the immune system depending on cellular context and the availability of effector proteins.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI27-910)
Fournisseur:
ProSci Inc.
Description:
Tight junctions represent one mode of cell-to-cell adhesion in epithelial or endothelial cell sheets, forming continuous seals around cells and serving as a physical barrier to prevent solutes and water from passing freely through the paracellular space. These junctions are comprised of sets of continuous networking strands in the outwardly facing cytoplasmic leaflet, with complementary grooves in the inwardly facing extracytoplasmic leaflet. The protein encoded by this gene, a member of the claudin family, is an integral membrane protein and a component of tight junction strands. It is found primarily in the kidneys, specifically in the thick ascending limb of Henle, where it acts as either an intercellular pore or ion concentration sensor to regulate the paracellular resorption of magnesium ions. Defects in this gene are a cause of primary hypomagnesemia, which is characterized by massive renal magnesium wasting with hypomagnesemia and hypercalciuria, resulting in nephrocalcinosis and renal failure.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI91-287)
Fournisseur:
ProSci Inc.
Description:
VCAM-1 is a single-pass type I membrane protein, contains 7 Ig-like C2-type domains. It is an endothelial ligand for very late antigen-4 (VLA-4) and alpha4ß7 integrin expressed on leukocytes, and thus mediates leukocyte-endothelial cell adhesion and signal transduction. VCAM-1 expression is induced on endothelial cells during inflammatory bowel disease, atherosclerosis, allograft rejection, infection, and asthmatic responses. During these responses, VCAM-1 forms a scaffold for leukocyte migration. VCAM-1 also activates signals within endothelial cells resulting in the opening of an "endothelial cell gate" through which leukocytes migrate. VCAM-1 has been identified as a potential anti-inflammatory therapeutic target, the hypothesis being that reduced expression of VCAM-1 will slow the development of atherosclerosis. In addition, VCAM-1-activated signals in endothelial cells are regulated by cytokines indicating that it is important to consider both endothelial cell adhesion molecule expression and function during inflammatory processes.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI55-080)
Fournisseur:
ProSci Inc.
Description:
This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. [provided by RefSeq].
UOM:
1 * 400 µl
New Product
Fournisseur:
iST Scientific Ltd
Description:
Film perméable aux gaz, transparent et perforé pour les plaques en PP, PE, PS et COC. Idéal pour l'incubation à court terme, l'agriculture et le stockage de semences, le stockage d'insectes, les cultures cellulaires.
Numéro de catalogue:
(PRSI96-478)
Fournisseur:
ProSci Inc.
Description:
Interleukin-6 receptor subunit beta (IL6ST) is also known as IL-6 receptor subunit beta, IL-6R subunit beta, IL-6R-beta, IL-6RB, Interleukin-6 signal transducer, Membrane glycoprotein 130 (gp130), CD130, Oncostatin-M receptor subunit alpha and Il6st,which is single-pass type I membrane protein. IL6ST /gp130 /CD130 can be found in tissues such as brain, heart, thymus, spleen, kidney, lung and liver and found in all the cell lines tested except BaF-B03.The expression of IL-6ST /gp130 is not restricted to IL6-responsive cells. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize gp130 for initiating signal transmission. IL6ST /CD130 can bind to IL6 /IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduce the signal. IL6ST /GP130 does not bind IL6 and may have a role in embryonic development.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI4381)
Fournisseur:
ProSci Inc.
Description:
Grik1 Antibody: Glutamate receptors are the predominant excitatory neurotransmitter receptors in the mammalian brain and are activated in a variety of normal neurophysiologic processes. Grik1, also known as glutamate receptor 5, belongs to the kainate family of glutamate receptors, which are composed of four subunits and function as ligand-activated ion channels. Grik1 is expressed in GABAergic interneurons of the hippocampus and are thought to participate in the formation of various subtypes of kainate receptors with Grik2 and KA2. Stimulation of Grik1 leads to intracellular calcium release and activation of protein kinase C. Excessive activation has been associated with psychiatric, neurological and neurodegenerative diseases. Numerous isoforms of Grik1 are known to exist and may be subject to RNA editing within the second transmembrane domain, which is thought to alter the properties of ion flow.
UOM:
1 * 1 EA
Fournisseur:
Portwest
Description:
This single colour bib and brace has the features and benefits of the tried and tested S488 contrast bib and brace in a choice of two colours.
Numéro de catalogue:
(634-1027)
Fournisseur:
Thermo Fisher Scientific
Description:
Accessoire pour spectrophotomètre UV/Vis, Porte-cuve thermostatable (jusqu'à un trajet optique de 50 mm), Pour: AquaMate Plus/UV10
UOM:
1 * 1 ST
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