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Fournisseur:  Bioss
Description:   This gene encodes a protein that is related to chondromodulin-I, which is a cartilage-specific glycoprotein that functions to stimulate chondrocyte growth and to inhibit tube formation of endothelial cells. This protein is also an angiogenesis inhibitor. Genetic variation in this gene is associated with a risk for type 2 diabetes, central obesity and serum levels of systemic immune mediators in a body size-dependent manner. This gene is also a candidate gene for age-related macular degeneration, though a direct link has yet to be demonstrated. [provided by RefSeq, Sep 2009].
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Type IV collagen is the major structural component of glomerular basement membranes (GBM), forming a 'chicken-wire' meshwork together with laminins, proteoglycans and entactin/nidogen. Arresten, comprising the C-terminal NC1 domain, inhibits angiogenesis and tumor formation. The C-terminal half is found to possess the anti-angiogenic activity. Specifically inhibits endothelial cell proliferation, migration and tube formation. Inhibits expression of hypoxia-inducible factor 1alpha and ERK1/2 and p38 MAPK activation. Ligand for alpha1/beta1 integrin (By similarity).
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-15385R-A555)

Fournisseur:  Bioss
Description:   Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalised into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown (By similarity).
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO (By similarity).
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP2 beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.
UOM:  1 * 100 µl
Fournisseur:  Biotium
Description:   TIMP3 (tissue inhibitor of metalloproteinases 3), along with family members TIMP1, TIMP2, and TIMP4, are inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix (ECM). An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP s inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes.
Numéro de catalogue: (BOSSBS-1546R)

Fournisseur:  Bioss
Description:   Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP2 beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.
UOM:  1 * 100 µl
Fournisseur:  Biotium
Description:   TIMP3 (tissue inhibitor of metalloproteinases 3), along with family members TIMP1, TIMP2, and TIMP4, are inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix (ECM). An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP s inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes.
Fournisseur:  NABERTHERM
Description:   These furnaces feature heating elements on supporting tubes that radiate freely into the chamber, ensuring particularly short heating times. With the robust lightweight refractory brick insulation, they can reach a max. working temperature of 1300 °C.
Fournisseur:  Bohlender
Description:   PPS screw cap, blue, distributor body made from PTFE.
Fournisseur:  DELTALAB
Description:   Clear polystyrene (PS).

Fournisseur:  VWR Collection
Description:   Conçu pour un grand nombre d'applications d'agitation, par ex. cultures cellulaires, études de solubilité, suspensions bactériennes ou applications de mélange classiques. La plate-forme grande capacité pour accueillir jusqu'à 15,9 kg. Commande de vitesse variable par microprocesseur permettant une agitation uniforme. Pour plus de sécurité, les agitateurs accroissent progressivement leur vitesse jusqu'à la valeur programmée. Le système d'agitation Accu-drive permet un contrôle de la vitesse, une précision, une sécurité et une durabilité exceptionnels : il assure un contrôle continu de la vitesse d'agitation et maintient la valeur programmée même en cas de changement de charge. Précision de la vitesse affichée à 1% de la vitesse définie (lorsque la vitesse est au-dessus de 100 min⁻¹).
UOM:  1 * 1 ST
Environmentally Preferable
Fournisseur:  VWR Collection
Description:   Digital stem thermometer suitable for field studies, wet lab applications, wash-down areas, food testing and tanks.
UOM:  1 * 1 ST
Fournisseur:  AMARELL, ARNO
Description:   These hydrometers are designed for the ranges of 0,600 up to 2,000 °SG.
Fournisseur:  Merck
Description:   Compatible avec de nombreux photomètres et ne nécessite aucune programmation pour mesurer les tests.
Numéro de catalogue: (REST22656)

Fournisseur:  Restek
Description:   The ProFLOW 6000 is designed with explosive and flammable gases.
UOM:  1 * 1 ST
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