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Fournisseur:  Bioss
Description:   Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-7525R-A647)

Fournisseur:  Bioss
Description:   This gene encodes a protein that is related to chondromodulin-I, which is a cartilage-specific glycoprotein that functions to stimulate chondrocyte growth and to inhibit tube formation of endothelial cells. This protein is also an angiogenesis inhibitor. Genetic variation in this gene is associated with a risk for type 2 diabetes, central obesity and serum levels of systemic immune mediators in a body size-dependent manner. This gene is also a candidate gene for age-related macular degeneration, though a direct link has yet to be demonstrated. [provided by RefSeq, Sep 2009].
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-6694R-A555)

Fournisseur:  Bioss
Description:   Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-6694R-A647)

Fournisseur:  Bioss
Description:   Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP-2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limb and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. Involved in the MTA1-mediated epigenetic regulation of ESR1 expression in breast cancer.
UOM:  1 * 100 µl
Fournisseur:  DWK Life Sciences
Description:   Seal, Sealing gasket, translucent silicone, OD 40,5 mm, ID 27,5 mm, 3 mm thick, Silicone
Numéro de catalogue: (BOSSBS-15385R-A350)

Fournisseur:  Bioss
Description:   Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalised into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown (By similarity).
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-15385R-A488)

Fournisseur:  Bioss
Description:   Key negative regulator of Shh signaling, which promotes the processing of GLI3 into GLI3R during neural tube development. Recruited by TULP3 and the IFT-A complex to primary cilia and acts as a regulator of the PKA-dependent basal repression machinery in Shh signaling by increasing cAMP levels, leading to promote the PKA-dependent processing of GLI3 into GLI3R and repress the Shh signaling. In presence of SHH, it is removed from primary cilia and is internalised into recycling endosomes, preventing its activity and allowing activation of the Shh signaling. Its ligand is unknown (By similarity).
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-1544R-CY3)

Fournisseur:  Bioss
Description:   Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO (By similarity).
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-1544R-CY5)

Fournisseur:  Bioss
Description:   Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO (By similarity).
UOM:  1 * 100 µl
Fournisseur:  MOINEAU
Description:   These 2-channel thermometers feature an electronic digital LCD with dual display of internal and extrenal temperatures.
Numéro de catalogue: (BOSSBS-5863R-CY7)

Fournisseur:  Bioss
Description:   Expressed in epithelial cells of the colon, fallopian tube, skin, breast, prostate, epididymis, liver, pancreatic islets and bile ducts, as well as by vascular endothelial cells, smooth muscle cells, fibroblasts, cortical and ganglionic neurons and cardiac myocytes. Also expressed by malignant epithelial cells in colon cancer, as well as breast, prostate, renal and skin tumors. Expression is significantly reduced in colon cancer compared to normal colon.
UOM:  1 * 100 µl
Fournisseur:  Greiner Bio-One
Description:   PP tubes designed to work with the MicroRack tube storage system.
Environmentally Preferable
Numéro de catalogue: (BOSSBS-12356R-A647)

Fournisseur:  Bioss
Description:   ALX1 is a 326 amino acid protein specific to cervix and cartilage tissues. As well as having a homeobox domain, ALX1 also contains an OAR domain, which has been suggested to be important for DNA binding or protein-protein interactions and transactivation. First characterized from a rat chondrosarcoma tumor cell line, ALX1 is a homeobox transcription factor that regulates downstream target genes and has specifically shown to act as a transcriptional repressor for rat prolactin in vivo. Homozygous ALX1 deficient mice are born with acrania and meroanencephaly, suggesting ALX1 function in the development of the neural tube. It has also been suggested that ALX1 cooperates with ALX4 in limb development and craniofacial bone formation.
UOM:  1 * 100 µl
Fournisseur:  Lenz Laborglas GmbH & CO.KG
Description:   DURAN®, verre borosilicaté, transparent.
Fournisseur:  Bohlender
Description:   Grâce au design spécial, les deux moitiés peuvent être tournées individuellement et les pièces raccordées peuvent être arrangées. Cette construction offre une très grande stabilité. Une lèvre de joint au tuyau avec un joint en FKM permet une très bonne étanchéité du filetage.
Fournisseur:  Avantor
Description:   Le distributeur cycle-tap est une unité distributrice de solvant en acier inoxydable munie d'un raccord conçue pour distribuer manuellement un solvant sans en mesurer la quantité précise.
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