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Single-use+Pressure+Sensor
Numéro de catalogue:
(BOSSBS-3968R-HRP)
Fournisseur:
Bioss
Description:
AMP/ATP-binding subunit of AMP-activated protein kinase (AMPK), an energy sensor protein kinase that plays a key role in regulating cellular energy metabolism. In response to reduction of intracellular ATP levels, AMPK activates energy-producing pathways and inhibits energy-consuming processes: inhibits protein, carbohydrate and lipid biosynthesis, as well as cell growth and proliferation. AMPK acts via direct phosphorylation of metabolic enzymes, and by longer-term effects via phosphorylation of transcription regulators. Also acts as a regulator of cellular polarity by remodeling the actin cytoskeleton; probably by indirectly activating myosin. Gamma non-catalytic subunit mediates binding to AMP, ADP and ATP, leading to activate or inhibit AMPK: AMP-binding results in allosteric activation of alpha catalytic subunit (PRKAA1 or PRKAA2) both by inducing phosphorylation and preventing dephosphorylation of catalytic subunits. ADP also stimulates phosphorylation, without stimulating already phosphorylated catalytic subunit. ATP promotes dephosphorylation of catalytic subunit, rendering the AMPK enzyme inactive.
UOM:
1 * 100 µl
Numéro de catalogue:
(PRSI25-186)
Fournisseur:
ProSci Inc.
Description:
TRIM21 is a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. TRIM21 is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus.This gene encodes a member of the tripartite motif (TRIM) family. The TRIM motif includes three zinc-binding domains, a RING, a B-box type 1 and a B-box type 2, and a coiled-coil region. The encoded protein is part of the RoSSA ribonucleoprotein, which includes a single polypeptide and one of four small RNA molecules. The RoSSA particle localizes to both the cytoplasm and the nucleus. RoSSA interacts with autoantigens in patients with Sjogren syndrome and systemic lupus erythematosus. Alternatively spliced transcript variants for this gene have been described but the full-length nature of only one has been determined. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
UOM:
1 * 50 µG
Numéro de catalogue:
(BSBTPB9096)
Fournisseur:
BosterBio
Description:
Polyclonal antibody for CD45/PTPRC detection. Host: Rabbit.Size: 100μg/vial. Tested applications: IHC-P. Reactive species: Human. CD45/PTPRC information: Molecular Weight: 147254 MW; Subcellular Localization: Membrane ; Single-pass type I membrane protein . Membrane raft . Colocalized with DPP4 in membrane rafts.
UOM:
1 * 1 EA
Numéro de catalogue:
(BOSSBS-5221R-A647)
Fournisseur:
Bioss
Description:
This gene encodes a nuclear phosphoprotein that plays a role in maintaining genomic stability, and it also acts as a tumor suppressor. The encoded protein combines with other tumor suppressors, DNA damage sensors, and signal transducers to form a large multi-subunit protein complex known as the BRCA1-associated genome surveillance complex (BASC). This gene product associates with RNA polymerase II, and through the C-terminal domain, also interacts with histone deacetylase complexes. This protein thus plays a role in transcription, DNA repair of double-stranded breaks, and recombination. Mutations in this gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Alternative splicing plays a role in modulating the subcellular localization and physiological function of this gene. Many alternatively spliced transcript variants, some of which are disease-associated mutations, have been described for this gene, but the full-length natures of only some of these variants has been described. A related pseudogene, which is also located on chromosome 17, has been identified. [provided by RefSeq, May 2009].
UOM:
1 * 100 µl
Numéro de catalogue:
(SARS95.1995)
Fournisseur:
SARSTEDT
Description:
Ces feuilles en aluminium perforables de 38 µm sont résistantes à la chaleur et aux solvants.
UOM:
1 * 100 ST
 Il s'agit d'un élément MarketSource. Des frais supplémentaires peuvent s'appliquer.
Numéro de catalogue:
(PERCN9303812)
Fournisseur:
PerkinElmer
Description:
Pure Grade standard for AA and ICP-OES.
UOM:
1 * 1 ST
Numéro de catalogue:
(PRSI51-132)
Fournisseur:
ProSci Inc.
Description:
Reacts with CD95 (Fas/APO-1), a 46 kDa single chain type I glycoprotein of the tumour necrosis factor/nerve growth factor (TNF/NGF) receptor superfamily, expressed on a variety of normal and neoplastic cells. It seems that the antibody LT95 does not induce Fas mediated apoptosis, although it cross-blocks anti-Fas DX2 antibody that recognizes a functional epitope of Fas molecule.
UOM:
1 * 50 µG
Numéro de catalogue:
(664-0193)
Fournisseur:
HORIBA
Description:
Sonde à oxygène dissous
UOM:
1 * 1 ST
Numéro de catalogue:
(PRSI91-851)
Fournisseur:
ProSci Inc.
Description:
Human BTN3A3, also known as butyrophilin subfamily 3 member A3 and BTF3, is a Single-pass type I membrane protein which belongs to the immunoglobulin superfamily and BTN/MOG family. The butyrophilin (BTN) genes are a group of major histocompatibility complex (MHC)-associated genes that encode type I membrane proteins with 2 extracellular immunoglobulin domains and an intracellular B30.2 (PRYSPRY) domain. It can be detected in peripheral blood mononuclear cells, T-cells l, spleen and lymphocytes. BTN3A3 plays a role in T-cell responses in the adaptive immune response.
UOM:
1 * 50 µG
Fournisseur:
VISTALAB TECHNOLOGIES
Description:
VITON seal kit for Ovation 100 - 1000 µl (QS), 201 - 1000 µl (F1 and F2), Pour: Vistalab Ovation Electronic
Fournisseur:
EPPENDORF
Description:
Transition from the tedious process of alternate well pipetting or vessel reformatting with single-channel pipettes to a more efficient manual liquid handling with 384-well plates with one of these starter sets. Each starter set includes a mechanical Eppendorf Research® Plus or electronic Eppendorf Xplorer® Plus multi-channel pipette and a total of 19200 ep Dualfilter T.I.P.S.® 384 filter tips (50 racks of 384 tips) in 'PCR clean and Sterile' grade.
Fournisseur:
Corning
Description:
Silicone sealing mats suitable for deep well plates and for thermal cyclers with screw down lids.
Numéro de catalogue:
(VIST8066)
Fournisseur:
VISTALAB TECHNOLOGIES
Description:
MLA pipette nozzle insert, white, MLA
UOM:
1 * 10 ST
Numéro de catalogue:
(732-7509)
Fournisseur:
Corning
Description:
Pour le scellage de microplaques PCR à 96 et 384 puits.
UOM:
1 * 100 ST
Fournisseur:
THERMO MATRIX TECHNOLOGIES
Description:
Tapis à bouchons ronds ou carrés pour la fermeture de plaques de stockage à 96 puits.
Fournisseur:
Corning
Description:
Le film poreux scelle les plaques de culture cellulaire en PP et PS, les plaques à 96 et 384 puits, ainsi que d'autres plaques d'analyse.
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