Single-use+Pressure+Sensor
Numéro de catalogue:
(PRSI91-431)
Fournisseur:
ProSci Inc.
Description:
Interferon alpha/ beta Receptor 2 (IFN- alpha/ beta R2) is a single-pass type I membrane protein which belongs to the type II cytokine receptor family. It complexes with IFN- alpha/ beta R1 to form the signaling receptor complex for the family of alpha and beta IFN subtypes. By alternative splicing, IFN- alpha/ beta R2 can exist as a secreted soluble protein or as a type I membrane protein. IFN- alpha/ beta R2 is the principal ligand binding subunit of the receptor. Ligand binding is stabilized by the subsequent association with IFN- alpha/ beta R1, resulting in the formation of a signaling ternary receptor complex. IFNAR2 was detected in most lymphocytes, monocytes, and granulocytes, although IFNAR2 expression was higher in the monocytes and granulocytes than in the lymphocytes. Among the lymphocyte subsets, IFNAR2 showed high expression in natural killer (NK) cells and low expression in T lymphocytes. Isoform 1 and isoform 3 of IFNAR2 are directly involved in signal transduction due to their interaction with the TYR kinase, JAK1. Isoform 1 also interacts with the transcriptional factors, STAT1 and STAT2. Both forms are potent inhibitors of type I IFN activity.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-946)
Fournisseur:
ProSci Inc.
Description:
Tumor necrosis factor receptor superfamily member 12A(Tnfrsf12a) is a single-pass type I membrane protein and contains 1 TNFR-Cys repeat. It is weak inducer of apoptosis in some cell types.It promotes angiogenesis and it is the proliferation of endothelial cells. It may modulate cellular adhesion to matrix proteins.TNFR binds specifically to tumor necrosis factor (TNF) and blocks its interaction with cell surface TNF receptors. TNF is a naturally occurring cytokine that is involved in normal inflammatory and immune responses. It plays an important role in the inflammatory processes of rheumatoid arthritis (RA), polyarticular-course juvenile rheumatoid arthritis (JRA), and ankylosing spondylitis and the resulting joint pathology. In addition, TNF plays a role in the inflammatory process of plaque psoriasis. Elevated levels of TNF are found in involved tissues and fluids of patients with RA, psoriatic arthritis, ankylosing spondylitis (AS), and plaque psoriasis. Two distinct receptors for TNF (TNFRs), a 55 kilodalton protein (p55) and a 75 kilodalton protein (p75), exist naturally as monomeric molecules on cell surfaces and in soluble forms. Biological activity of TNF is dependent upon binding to either cell surface TNFR.
UOM:
1 * 50 µG
Fournisseur:
Portwest
Description:
This single colour bib and brace has the features and benefits of the tried and tested S488 contrast bib and brace in a choice of two colours.
Numéro de catalogue:
(733-1617)
Fournisseur:
LONZA
Description:
Le système FlashGel™ pour ARN est optimisé pour les besoins uniques de l'ARN et pour l'analyse rapide de l'intégrité des échantillons. Un ARN intact et de grande qualité est essentiel pour des résultats reproductibles en matière d'expression génétique, d'analyse Northern, de construction de bibliothèques d'ADN complémentaire et de marquage de l'ADN complémentaire pour les microarrays. La plupart des protocoles recommande de contrôler l'ARN avant l'analyse en aval.
UOM:
1 * 9 ST
Fournisseur:
DWK Life Sciences
Description:
Network Interface is a single-line network adapter for up to 255 R₂P units.
Numéro de catalogue:
(662-1786)
Fournisseur:
VWR Collection
Description:
Sonde de température, câble d'un mètre (pH 1001), VWR®, Pour: VWR pH 110
UOM:
1 * 1 ST
Numéro de catalogue:
(PRSI25-595)
Fournisseur:
ProSci Inc.
Description:
ATP5G2 is a subunit of mitochondrial ATP synthase. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, F0, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and single representatives of the gamma, delta, and epsilon subunits. The proton channel likely has nine subunits (a, b, c, d, e, f, g, F6 and 8). There are three separate genes which encode subunit c of the proton channel and they specify precursors with different import sequences but identical mature proteins. ATP5G2 is one of three precursors of subunit c.This gene encodes a subunit of mitochondrial ATP synthase. Mitochondrial ATP synthase catalyzes ATP synthesis, utilizing an electrochemical gradient of protons across the inner membrane during oxidative phosphorylation. ATP synthase is composed of two linked multi-subunit complexes: the soluble catalytic core, F1, and the membrane-spanning component, F0, comprising the proton channel. The catalytic portion of mitochondrial ATP synthase consists of 5 different subunits (alpha, beta, gamma, delta, and epsilon) assembled with a stoichiometry of 3 alpha, 3 beta, and single representatives of the gamma, delta, and epsilon subunits. The proton channel likely has nine subunits (a, b, c, d, e, f, g, F6 and 8). There are three separate genes which encode subunit c of the proton channel and they specify precursors with different import sequences but identical mature proteins. The protein encoded by this gene is one of three precursors of subunit c. Alternatively spliced transcript variants encoding different isoforms have been identified. This gene has multiple pseudogenes.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-513)
Fournisseur:
ProSci Inc.
Description:
CD19 is a single-pass type I membrane protein containing 2 Ig-like C2-type (immunoglobulin-like) domains. CD19 is expressed on follicular dendritic cells and B cells. In fact, it is present on B cells from earliest recognizable B-lineage cells during development to B-cell blasts but is lost on maturation to plasma cells. CD19 primarily acts as a B cell co-receptor in conjunction with CD21 and CD81. Upon activation, the cytoplasmic tail of CD19 becomes phosphorylated, which leads to binding by Src-family kinases and recruitment of PI-3 kinase. CD19 Assembles with the antigen receptor of B lymphocytes in order to decrease the threshold for antigen receptor-dependent stimulation. Defects in CD19 are the cause of immunodeficiency common variable type 3 (CVID3) which is a primary immunodeficiency characterized by antibody deficiency, hypogammaglobulinemia, recurrent bacterial infections and an inability to mount an antibody response to antigen.
UOM:
1 * 50 µG
Fournisseur:
iST Scientific Ltd
Description:
Film perméable aux gaz, transparent et perforé pour les plaques en PP, PE, PS et COC. Idéal pour l'incubation à court terme, l'agriculture et le stockage de semences, le stockage d'insectes, les cultures cellulaires.
Numéro de catalogue:
(730-0109)
Fournisseur:
THERMO OWL SCIENTIFIC
Description:
Ces cuves constituent un moyen simple, pratique et rapide de criblage de plusieurs échantillons dans un seul gel d'agarose. Elles permettent le criblage d'échantillons PCR, les préparations de plasmide, la cartographie de restriction et le clonage.
UOM:
1 * 1 ST
Numéro de catalogue:
(634-1027)
Fournisseur:
Thermo Fisher Scientific
Description:
Accessoire pour spectrophotomètre UV/Vis, Porte-cuve thermostatable (jusqu'à un trajet optique de 50 mm), Pour: AquaMate Plus/UV10
UOM:
1 * 1 ST
Numéro de catalogue:
(PRSI91-354)
Fournisseur:
ProSci Inc.
Description:
SLAM Family Member 6 (SLAMF6) is a 60 kD single-pass type I membrane protein that belongs to the SLAM subgroup of the CD2 family. Human SLAMF6/ NTB-A contains a 205 amino acid extracellular domain (ECD) with one Ig-like V-set and one Ig-like C2-set domain, a 21 amino acid transmembrane segment and an 84 amino acid cytoplasmic domain, with two immunoreceptor tyrosine-based switch motifs. SLAMF6 is a homodimer. SLAMF6 can interact with PTN6 and, upon phosphorylation, with PTN11 and SH2D1A/SAP. Phosphorylation-dependent NTB-A association with SAP is required for full production of IFN- gamma by NK cells and independent of EAT-2 binding. It Triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. On B cells, NTB-A modulates immunoglobulin class switching and the balance between tolerance and autoimmunity.
UOM:
1 * 50 µG
Numéro de catalogue:
(HACHE51M001)
Fournisseur:
Hach
Description:
This temperature sensor features a glass body, fixed cable and 10 kohm resistance thermistor. The T201's cinch (RCA) connector compatible with radiometer PHM2xx, CDM2xx, PHM9x, IONxxx and TIMxxx meters.
UOM:
1 * 1 ST
Numéro de catalogue:
(BE-201)
Fournisseur:
G-Biosciences
Description:
Ce kit enseigne les techniques de manipulation aseptiques et la culture de bactéries en milieu de culture liquide et sur des plaques de gélose en phase solide. Ce kit est conçu pour éduquer les étudiants aux différentes étapes du cycle de prolifération bactérienne, à savoir temps mort, phases logarithmique ou exponentielle, stationnaire et dégénérescente ou mort. Ce kit traite également de l'importance de la prolifération des bactéries sur des plaques de gélose en phase solide pour isoler des colonies uniques de bactéries. Cette activité de laboratoire passe par la préparation d'un milieu de culture et de plaques de gélose solide.
UOM:
1 * 1 KIT
Numéro de catalogue:
(PRSI55-080)
Fournisseur:
ProSci Inc.
Description:
This gene encodes a common acute lymphocytic leukemia antigen that is an important cell surface marker in the diagnosis of human acute lymphocytic leukemia (ALL). This protein is present on leukemic cells of pre-B phenotype, which represent 85% of cases of ALL. This protein is not restricted to leukemic cells, however, and is found on a variety of normal tissues. It is a glycoprotein that is particularly abundant in kidney, where it is present on the brush border of proximal tubules and on glomerular epithelium. The protein is a neutral endopeptidase that cleaves peptides at the amino side of hydrophobic residues and inactivates several peptide hormones including glucagon, enkephalins, substance P, neurotensin, oxytocin, and bradykinin. This gene, which encodes a 100-kD type II transmembrane glycoprotein, exists in a single copy of greater than 45 kb. The 5' untranslated region of this gene is alternatively spliced, resulting in four separate mRNA transcripts. The coding region is not affected by alternative splicing. [provided by RefSeq].
UOM:
1 * 400 µl
New Product
Fournisseur:
Endress+Hauser
Description:
COY8 Zero gel for oxygen sensors (cert. HE_01083_01.18), Sonde à oxygène dissous
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