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Single-use+Pressure+Sensor
Numéro de catalogue:
(663-2101)
Fournisseur:
KNICK
Description:
This bench top meter can be operated with either 2-electrode or 4-electrode sensors. In conjunction with the Knick ZU 6985 4-electrode sensor, the meter functions reliably over a wide conductivity range from <1,00 to >1000 mS/cm.
UOM:
1 * 1 ST
Numéro de catalogue:
(PRSI91-262)
Fournisseur:
ProSci Inc.
Description:
Z-DNA Binding Protein 1 (ZBP1) is a protein with 2 DRADA repeats. ZBP1 is highly expressed in lymphatic tissues including lymph node, leukocytes, tonsil, bone marrow, and spleen. ZBP1 participates in the detection of viral and bacterial DNA from by the host's innate immune system. It plays a role in host defense against tumors and pathogens. ZBP1 Acts as a cytoplasmic DNA sensor which, when activated, induces the recruitment of TBK1 and IRF3 to its C-terminal region and activates the downstream interferon regulatory factor (IRF) and NF-kappa B transcription factors, leading to type-I interferon production. ZBP1-induced NF-kappaB activation probably involves the recruitment of the RHIM containing kinases RIPK1 and RIPK3.
UOM:
1 * 50 µG
Fournisseur:
Mettler - Toledo
Description:
Metal half-cells for Redox/ORP applications.
Numéro de catalogue:
(CONSSP22Y)
Fournisseur:
CONSORT
Description:
Électrode, pH, Double jonction, scellée, pH: 0 - 14, +5...+110 °C, Verre, Membrane: Double junction, Électrolyte: Sealed, Ø×L: 12×110 mm, S8, Pour: Alkaline solutions, high temperature fluids, photo baths, ink
UOM:
1 * 1 ST
Fournisseur:
Heidolph Instruments GmbH & Co.KG
Description:
Modèles SP quick 1,6 et 2,5 mm.
Fournisseur:
EBRO
Description:
Sonde pour thermomètre infrarouge, Ø×L: 3×120 mm
Fournisseur:
TESTO
Description:
Sonde de température, −40…+125 °C, 170 mm
Numéro de catalogue:
(PRSI90-413)
Fournisseur:
ProSci Inc.
Description:
CD152 (CTLA-4) and CD28, together with their ligands B7-1 and B7-2, constitute one of the dominant costimulatory pathways that regulate T and B cell responses. CD152 and CD28 are structurally
homologous molecules that are members of the immunoglobulin (Ig) gene superfamily. Both CD152 and CD28 are composed of a single Ig V-like extracellular domain, a transmembrane domain and an intracellular domain. CD152 and CD28 are both expressed on the cell surface as disulfide-linked homodimers or as monomers. CD152 was originally identified as a gene that was specifically expressed by cytotoxic T lymphocytes. However, CD152 transcripts have since been found in both Th1 and Th2, and CD4+ and CD8+ T cell clones. Whereas, CD28 expression is constitutive on the surfaces of 95% of CD4+ T cells and 50% of CD8+ T cells and is down regulated upon T cell activation, CD152 expression is upregulated rapidly following T cell activation and peaks approximately 24 hours following activation. Although both CD152 and CD28 can bind to the same ligands, CD152 binds to B71 and B72 with 20-100-fold higher affinity than CD28.
UOM:
1 * 1 EA
Numéro de catalogue:
(EDVO990)
Fournisseur:
EDVOTEK
Description:
Lorsque des cellules normales sont mises en culture, leur croissance s'arrête lorsqu'elles deviennent trop nombreuses (inhibition de contact). Les cellules cancéreuses en culture se multiplient de manière incontrôlée parce qu'elles ont perdu cette faculté. C'est ce qui permet aux tumeurs de se former dans le corps. Par ailleurs, de nombreux types de cellules différents peuvent coexister dans une seule tumeur. Cette expérience permet aux étudiants de découvrir les différences entre les cellules normales et les cellules cancéreuses, sur le plan de leur croissance et de leurs caractéristiques.
UOM:
1 * 1 ST
Fournisseur:
Sartorius
Description:
L'arium® mini est exclusivement composé de matériaux de haute qualité. Avec son interface intuitive, son système de sachet fermé et son «aqua stop» arium® pratique, l'unité est idéale pour une consommation quotidienne allant jusqu'à 10 L d'eau ultrapure.
Numéro de catalogue:
(PRSI90-394)
Fournisseur:
ProSci Inc.
Description:
CD40 is a member of the TNF receptor superfamily which are single transmembrane-spanning glycoproteins and plays an essential role in mediating a broad variety of immune and inflammatory responses including T cell-dependent immunoglobulin class switching, memory B cell development, and germinal center formation. CD40 contains 4 cysteine-rich repeats in the extracellular domain and is expressed in B cells, dendritic cells, macrophages, endothelial cells and several tumour cell lines. The cognate interaction between CD40 and CD40 ligand (CD154) on T cells activates NF-kappaB, Jun N-terminal kinase and Janus kinase signal transducers and activators of transcription pathways. Several different TRAF proteins (adapter proteins) have been identified to serve as mediators of the signal transduction. In addition, CD40/CD40L interaction is found to be necessary for amyloid-beta-induced microglial activation and thus is thought to be an early event in Alzheimer disease pathogenesis. Defects in CD40 result in hyper-IgM immunodeficiency type 3 (HIGM3), an autosomal recessive disorder characterised by the inability of B cells to undergo isotype switching, as well as an inability to mount an antibody-specific immune response and a lack of germinal center formation.
UOM:
1 * 1 EA
Fournisseur:
IKA
Description:
Calorimètre compact semi-automatique pour déterminer le pouvoir calorifique d'échantillons liquides et solides.
Numéro de catalogue:
(PRSI90-327)
Fournisseur:
ProSci Inc.
Description:
Zinc-alpha-2-glycoprotein (ZAG), first identified in the 1960s, derives its name from its precipitation from human plasma upon the addition of zinc salts. ZAG has since been found in secretory epithelial cells and in a range of body fluids. ZAG is identical to a lipid mobilizing factor isolated from the urine of patients with cancer cachexia and stimulates lipolysis in in vitro and in vivo experiments. Due to its expression in, and secretion from adipocytes, ZAG is considered an adipokine. Recently the clinical significance of ZAG has been clarified. ZAG expression in adipocytes is inversely related to fat mass, thus it is intimately involved in the maintenance of body weight in mice and humans. Epidemiological studies have uncovered an association between ZAG and plasma cholesterol. The non-synonymous single nucleotide polymorphism rs4215 in ZAG is associated with plasma cholesterol and obesity. Structurally ZAG possesses a class I major histocompatibility complex (MHC) protein fold. It is distinct from other members of this protein family in that it is soluble, rather than being anchored to plasma membranes, and it associates with prolactin inducible protein rather than beta2-microglobulin. Similar to peptide antigen-presenting class I MHC molecules, ZAG possesses an open apical groove between its alpha1 and alpha2 domain helices.
UOM:
1 * 50 µG
Fournisseur:
BEHR
Description:
Complete compact extraction system with basic rack, heating device, holder, tubing and glassware (reaction flasks, extractor, Dimroth condenser for extraction).
Fournisseur:
Thermo Orion
Description:
This benchtop meter is ideal for a wide range of applications and advanced pH and conductivity analysis in the lab. It offers two measuring channels allowing users to measure pH and conductivity simultaneously or view each channel separately.
Numéro de catalogue:
(BIND8012-1747)
Fournisseur:
Binder
Description:
Pt 100 temperature sensor, interior, for displaying the temperature on the unit display, KBF P series
UOM:
1 * 1 ST
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