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Single-use+Temperature+Sensor
Numéro de catalogue:
(PRSI91-236)
Fournisseur:
ProSci Inc.
Description:
Heat-Responsive Protein 12 (HRSP12) is an endoribonuclease that belongs to the Rut family. HRSP12 is found mainly in the human adult kidney and liver and is responsible for inhibiting protein translation by cleaving mRNA. HRSP12 only cleaves phosphodiester bonds in single-stranded RNA and inhibits cell-free protein synthesis. The levels of both mRNA and protein are markedly reduced in heptatocellular tumors and in human hepatoma cell lines compared with normal liver tissues. Moreover the levels of HRSP12 are different depending on the grade of the tumor. This had led to the suggestion that HRSP12 may be an important biomarker for heptatic carcinoma.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-516)
Fournisseur:
ProSci Inc.
Description:
T-Cell Surface Glycoprotein CD3 epsilon Chain (CD3 epsilon ) is a single-pass type I membrane protein. CD3 epsilon contains 1 Ig-like (immunoglobulin-like) domain and 1 ITAM domain. CD3 epsilon is a polypeptide encoded by the CD3E gene on chromosome 11 in humans. The T cell receptor-CD3 complex (TCR/CD3 complex) is involved in T-cell development and several intracellular signal-transduction pathways. This complex is critical for T-cell development and function, and represents one of the most complex transmembrane receptors. The T cell receptor-CD3 complex is unique in having ten cytoplasmic immunoreceptor tyrosine-based activation motifs (ITAMs). TCR/CD3 complex plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways.
UOM:
1 * 50 µG
Fournisseur:
Simport Scientific
Description:
Films adhésifs de scellage transparents spécialement conçus pour réduire la contamination croisée et/ou les débordements dans les applications PCR. Thermostables et fonctionnels de −70 °C à +95 °C.
Numéro de catalogue:
(PRSI91-881)
Fournisseur:
ProSci Inc.
Description:
B- and T-Lymphocyte Attenuator (BTLA) is a single-pass type I membrane protein containing 1 Ig-like V-type (immunoglobulin-like) domain. BTLA expression is induced during activation of T cells, and BTLA remains expressed on Th1 cells but not Th2 cells. Like PD1 and CTLA4, BTLA interacts with a B7 homolog, B7H4. However, unlike PD-1 and CTLA-4, BTLA displays T-Cell inhibition via interaction with tumor necrosis family receptors (TNF-R), not just the B7 family of cell surface receptors. BTLA is a lymphocyte inhibitory receptor that inhibits lymphocytes during immune response. BTLA also is a ligand for tumor necrosis factor (receptor) superfamily, member 14 (TNFRSF14), also known as herpes virus entry mediator (HVEM). BTLA-HVEM complexes negatively regulate T-cell immune responses.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-304)
Fournisseur:
ProSci Inc.
Description:
Tumor necrosis factor receptor superfamily member 3, also known as Lymphotoxin-beta receptor,Tumor necrosis factor C receptor,Tumor necrosis factor receptor 2-related protein,Tumor necrosis factor receptor type III,LTBR,TNFCR, TNFR3 and TNFRSF3, is a member of the tumor necrosis factor (TNF) family of receptors. LTBR is a single-pass type I membrane protein and contains four TNFR-Cys repeats. It is expressed on the surface of most cell types, but not on T and B lymphocytes. LTBR and its ligand play a role in the development and organization of lymphoid tissue and transformed cells. Activation of LTBR can trigger apoptosis. In addition, LTBR can lead to the release of the cytokine interleukin 8.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-773)
Fournisseur:
ProSci Inc.
Description:
Bone Marrow Stromal Antigen 2 (BST2) is a single-pass type II membrane protein that belongs to the tetherin family. BST2 is predominantly expressed in the liver, lung, heart and placenta. BST2 is involved in the sorting of secreted proteins. BST2 is a human cellular protein which inhibits retrovirus infection by preventing the diffusion of virus particles after budding from infected cells. BST2 is initially discovered as an inhibitor to HIV-1 infection in the absence of Vpu, it has also been shown to inhibit the release of other viruses such as retroviruses, filoviruses, arenaviruses, and herpes viruses. BST2 may play a role in B-cell activation in rheumatoid arthritis.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-659)
Fournisseur:
ProSci Inc.
Description:
Trem-like transcript 2 protein (TLT2), also known as Triggering receptor expressed on myeloid cells-like protein 2, TLT2 and C6orf76, is single-pass type I membrane protein. TREML2 contains one Ig-like V-type domain, which can be induced in CD4 T-cell by concanavalin-A. As a cell surface receptor, TREML2 may play a role in the innate and adaptive immune response. TREML2 also acts as a counter-receptor for CD276 and interaction with CD276 on T-cells enhances T-cell activation. It has shown that TREML2 may be involved in the innate immune response based on its expression profile and the fact that it is up-regulated in response to inflammation.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI26-157)
Fournisseur:
ProSci Inc.
Description:
PTPRE is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. Two alternatively spliced transcript variants of this gene have been reported, one of which encodes a receptor-type PTP that possesses a short extracellular domain, a single transmembrane region, and two tandem intracytoplasmic catalytic domains; Another one encodes a PTP that contains a distinct hydrophilic N-terminus, and thus represents a nonreceptor-type isoform of this PTP. Studies of the similar gene in mice suggested the regulatory roles of this PTP in RAS related signal transduction pathways, cytokines induced SATA signaling, as well as the activation of voltage-gated K+ channels.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-836)
Fournisseur:
ProSci Inc.
Description:
Junctional Adhesion Molecule B (JAM-B) is a single-pass type I membrane protein that belongs to the juctional adhesion molecules family. JAM-B includes a signal sequence (aa 1-28), an extracellular region (aa 29-238) with one Ig-like C2-type domain and one Ig-like V-type domain, a transmembrane segment (aa 239-259), and a cytoplasmic domain (aa 260 - 298). JAMB is localized to the tight junctions between endothelial cells or epithelial cells. JAM-B is prominently expressed in the heart, placenta, lung, foreskin and lymph node. It is also present on the endothelia of other vessels. JAM-B acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs.
UOM:
1 * 50 µG
Numéro de catalogue:
(115-1893)
Fournisseur:
Texwipe
Description:
Lingettes une épaisseur en polyester à bord coupé, idéales pour le nettoyage des sols et l'application de solutions et de désinfectants sur les sols.
UOM:
1 * 340 ST
Numéro de catalogue:
(442-0809)
Fournisseur:
2MAG
Description:
Agitateur magnétique robuste avec boîtier hermétiquement fermé en acier inoxydable, idéal pour les milieux très visqueux. Températures de fonctionnement jusqu'à 50 °C.
UOM:
1 * 1 ST
Numéro de catalogue:
(AATB112310O0)
Fournisseur:
AAT BIOQUEST INC
Description:
The 12H7 monoclonal antibody binds to human CD123, a 70 kD single-pass type I membrane protein often located on the surface of macrophages, hematopoietic progenitors and dendritic cells. CD123 acts in vital cellular pathways, for instance, the cytokine-mediated signaling pathway. From a research standpoint, it is of biological interest due to its association with essential macromolecules/ligands like CD131.
UOM:
1 * 1 ST
New Product
Numéro de catalogue:
(TEXWTX2424)
Fournisseur:
Texwipe
Description:
Ces lingettes à épaisseur unique constituées intégralement de polyester à filaments continus sont très absorbantes.
UOM:
1 * 600 ST
Fournisseur:
Thermo Scientific
Description:
Ergonomically designed, the Thermo Scientific™ Multifuge X4F/X4FR Pro series floor-standing centrifuges have a touch screen interface that enables easier programming for quicker results and ability to access and track all runs, rotor life and centrifuge health information for maximum versatility and power at every turn.
Numéro de catalogue:
(PRSI55-295)
Fournisseur:
ProSci Inc.
Description:
mDnmt3L (DNA methyltransferase 3L) does not appear to be catalytically active due to loss of the critical active site residues. It may function not directly as a DNA methyltransferase but rather as a regulator of methylation at imprinted loci. It is required specifically for the establishment of genomic imprints but is dispensable for their propagation. It is essential for the de novo methylation of single-copy DNA sequences. The protein is well-express in testis, thymus, ovary, and heart. mDnmt3L, which belongs to the 5-cytosine methyltransferase family, contains 1 ADD-type zinc finger.
UOM:
1 * 400 µl
New Product
Fournisseur:
HORIBA
Description:
Ces appareils de mesure de poche étanches mesurent directement les concentrations de calcium, de potassium ou de sodium dans un échantillon de 0,3 ml (ou un échantillon de 0,05 ml avec une feuille d'échantillonnage B). Le capteur plan unique permet de mesurer des liquides visqueux, des solides et même des échantillons en poudre. Pas besoin de l'immerger dans l'échantillon, quelques gouttes suffisent.
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est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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