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Fournisseur:  Bioss
Description:   TLK1 is a nuclear serine/threonine kinases that are potentially involved in the regulation of chromatin assembly. TLK1 is rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly. Isoform 3 phosphorylates and enhances the stability of the t-SNARE SNAP23, augmenting its assembly with syntaxin.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-7832R-CY3)

Fournisseur:  Bioss
Description:   Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-7832R-CY7)

Fournisseur:  Bioss
Description:   Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-12486R-A647)

Fournisseur:  Bioss
Description:   Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-11788R-A680)

Fournisseur:  Bioss
Description:   The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-11788R-A750)

Fournisseur:  Bioss
Description:   The function of PrP is still under debate. May play a role in neuronal development and synaptic plasticity. May be required for neuronal myelin sheath maintenance. May play a role in iron uptake and iron homeostasis (By similarity). Isoform 2 may act as a growth suppressor by arresting the cell cycle at the G0/G1 phase. Soluble oligomers are toxic to cultured neuroblastoma cells and induce apoptosis (in vitro).
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-7778R-CY5)

Fournisseur:  Bioss
Description:   Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-7778R-A680)

Fournisseur:  Bioss
Description:   Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
UOM:  1 * 100 µl
Numéro de catalogue: (HI39-32-025-30)

Fournisseur:  HICHROM GAS CHROMATOGRAPHY
Description:   Application specifc column for free and total glycerine (phase stable up to 380 °C) and for FAMEs in biodiesel analysis.
UOM:  1 * 1 ST
Numéro de catalogue: (BOSSBS-3123R-CY3)

Fournisseur:  Bioss
Description:   The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq, Jul 2008].
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-7895R-CY5.5)

Fournisseur:  Bioss
Description:   Regulatory subunit for CDC7 which activates its kinase activity thereby playing a central role in DNA replication and cell proliferation. Required for progression of S phase. The complex CDC7-DBF4A selectively phosphorylates MCM2 subunit at 'Ser-40' and 'Ser-53' and then is involved in regulating the initiation of DNA replication during cell cycle.Tissue specificity: Highly expressed in testis and thymus. Expressed also in most cancer cells lines.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-3733R-CY5)

Fournisseur:  Bioss
Description:   The protein encoded by this gene is a regulatory protein involved in mitosis. The gene product complexes with p34(cdc2) to form the maturation-promoting factor (MPF). Two alternative transcripts have been found, a constitutively expressed transcript and a cell cycle-regulated transcript, that is expressed predominantly during G2/M phase. The different transcripts result from the use of alternate transcription initiation sites. [provided by RefSeq, Jul 2008].
UOM:  1 * 100 µl
Numéro de catalogue: (ENZOADI905770100)

Fournisseur:  ENZO LIFE SCIENCES
Description:   The DNA damage checkpoint is a signal transduction pathway that has the ability to delay entry into mitosis. When DNA is damaged, the Check point kinases (CHKs) are known to act downstream of ATM to elicit appropriate responses such as cell cycle arrest. Chk1, for instance, is activated by ATM phosphorylation of serines 123, 178, 278, and 292 of the S phase-promoting cdc25A phosphatase and accelerates IR (ionizing radiation)induced degradation of cdc25A.
UOM:  1 * 1 EA
New Product
Numéro de catalogue: (BOSSBS-0917R-A350)

Fournisseur:  Bioss
Description:   Bromodeoxyuridine is a synthetic nucleoside that is an analogue of thymidine. BrdU is incorporated into DNA during S-phase of a cell cycle. It is commonly used in the detection of proliferating cells in living tissues
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-0917R-A680)

Fournisseur:  Bioss
Description:   Bromodeoxyuridine is a synthetic nucleoside that is an analogue of thymidine. BrdU is incorporated into DNA during S-phase of a cell cycle. It is commonly used in the detection of proliferating cells in living tissues.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-9249R-A555)

Fournisseur:  Bioss
Description:   Catalytic subunit of the KPC complex that acts as E3 ubiquitin-protein ligase. Required for poly-ubiquitination and proteasome-mediated degradation of CDKN1B during G1 phase of the cell cycle.
UOM:  1 * 100 µl
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