Solid+Phase+Extraction
Fournisseur:
Cayman Chemical
Description:
1,4-Butanediol Dimethanesulfonate (Busulfan) is an alkyl sulfonate that acts as an alkylating antineoplastic agent. It forms both intra- and interstrand crosslinks on DNA. In mammals, busulfan causes profound and prolonged reduction in the generation of hematopoietic progenitors without significantly affecting lymphocyte levels and humoral antibody responses.
Fournisseur:
HUPFER METALLWERKE
Description:
These high quality and standardised shelving can be precisely adapted to all kinds of spaces and therefore makes optimal and economical use of the available storage area.
Numéro de catalogue:
(662-1628)
Fournisseur:
Hach
Description:
Électrodes combinées de pH en laboratoire 3 en 1 avec un capteur de température intégré.
UOM:
1 * 1 ST
Fournisseur:
Biotium
Description:
Nitric oxide donors, nitric oxide synthase inhibitors and nitric oxide detection reagents and kits for nitric oxide (NO) studies.
Fournisseur:
KGW
Description:
Dewar flask made of borosilicate glass 3,3. It is suitable for liquid or solid media's and solid matters.
Fournisseur:
Corning
Description:
These 96-well solid black and white polystyrene microplates are designed to reduce well-to-well cross-talk.
Numéro de catalogue:
(PRSI79-871)
Fournisseur:
ProSci Inc.
Description:
Key transcriptional regulator of type I interferon (IFN)-dependent immune responses and plays a critical role in the innate immune response against DNA and RNA viruses. Regulates the transcription of type I IFN genes (IFN-alpha and IFN-beta) and IFN-stimulated genes (ISG) by binding to an interferon-stimulated response element (ISRE) in their promoters. Acts as a more potent activator of the IFN-beta (IFNB) gene than the IFN-alpha (IFNA) gene and plays a critical role in both the early and late phases of the IFNA/B gene induction. Found in an inactive form in the cytoplasm of uninfected cells and following viral infection, double-stranded RNA (dsRNA), or toll-like receptor (TLR) signaling, becomes phosphorylated by IKBKE and TBK1 kinases. This induces a conformational change, leading to its dimerization and nuclear localization and association with CREB binding protein (CREBBP) to form dsRNA-activated factor 1 (DRAF1), a complex which activates the transcription of the type I IFN and ISG genes. Can activate distinct gene expression programs in macrophages and can induce significant apoptosis in primary macrophages.
UOM:
1 * 1 EA
Numéro de catalogue:
(90071.)
Fournisseur:
Biotium
Description:
Biotin ethylenediamine in free base form. White solid soluble in DMSO.
UOM:
1 * 25 mg
Fournisseur:
MP Biomedicals
Description:
(S)-(+)-Camptothecin binds irreversibly to the DNA-topoisomerase I complex, inhibiting the reassociation of DNA after cleavage by topoisomerase I and traps the enzyme in a covalent linkage with DNA.
Fournisseur:
GLASWARENFABRIK KARL HECHT
Description:
Separating funnels, Squibb, made of borosilicate glass 3.3, with solid glass plug or plug with PTFE key and plastic stopper.
Fournisseur:
Retsch GmbH
Description:
Sieves consist of a solid stainless steel sieve frame of high stability for reliable sieving results.
Fournisseur:
MOTIC
Description:
Microscope for basic work in biology life science. Fixed Koehler set-up, rackless stage, nice plan achromatic optics. The Motic BA 210 is robust and ready to use with pre-installed set-up of optics and halogen illumination, interchangeable with a LED module (LED to be purchased separately).
Numéro de catalogue:
(552-0129)
Fournisseur:
GERBER FUNKE DR N.
Description:
Chromatographie en couche mince (CCM/TLC), Modification de phase: Gel de silice, Matériau: Aluminium, Indicateur fluorescent: No, Dimensions de la plaque: 200×200 mm
UOM:
1 * 25 ST
Numéro de catalogue:
(116-1342)
Fournisseur:
KROSCHKE
Description:
Ces modes d'emploi standard en plastique reprennent les conseils de prudence, les procédures à suivre en cas de danger et les règles de conduite à tenir, au quotidien.
UOM:
1 * 1 ST
Fournisseur:
ATAGO
Description:
Accessory for benchtop refractometer, Liquide de contact - monobromonaphthaline, 4 ml, 1,63 nD, pour réfractomètres DR-A1, NAR-1T SOLID, NAR-2T, NAR-3T, NAR-4T, NAR 2T•HI
Numéro de catalogue:
(PRSI33-854)
Fournisseur:
ProSci Inc.
Description:
This antibody is specific to a conserved determinant of the p53 protein. PAb 122 binds to the C-terminus (aa 370-378) of both wild type and mutated p53. When microinjected into nuclei, PAb 122 blocked re-entry into the S-phase of the cell cycle. Mutation and/or allelic loss of p53 is one of the causes of a variety of mesenchymal and epithelial tumors. If it occurs in the germ line, such tumors run in families. p53 binds to a DNA consensus sequence, the p53 response element, and it regulates normal cell growth cycle events by activating transcription of genes, involved either in progression through the cycle, or causing arrest in G1 when the genome is damaged. In most transformed and tumor cells the concentration of p53 is increased 5-1000 fold over the minute concentrations (1000 molecules cell) in normal cells, principally due to the increased half-life (4 h) compared to that of the wild-type (20 min). The protein in the nucleus, but is detectable at the plasma membrane during mitosis and when certain mutations modulate cytoplasmic/nuclear distribution. Its the most commonly mutated gene in spontaneously occurring human cancers. Mutations arise with an average frequency of 70% but incidence varies from zero in carcinoid lung tumors to 97% in primary melanomas. High concentrations of p53 protein are transiently expressed in human epidermis and superficial dermal fibroblasts following mild ultraviolet irradiation.
UOM:
1 * 1 EA
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