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block+heaters+
Numéro de catalogue:
(PRSI76-964)
Fournisseur:
ProSci Inc.
Description:
The HTA125 monoclonal antibody specifically reacts with human CD284, a 110 kDa type I transmembrane signaling molecule known as the Toll-like Receptor 4 (TLR4). CD284 is an important molecule in the innate immunity response to bacterial lipoproteins. It is expressed by monocytes, macrophages, and endothelial cells. The HTA125 antibody can block Lipopolysaccharide-induced cytokine production and immunoprecipitate human TLR4.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(AATB39008)
Fournisseur:
AAT BIOQUEST INC
Description:
Trifluoromethyl phenyl diazirine maleimide is an excellent building block to develop photoactive probes by reacting with a thiol-containing biomolecule.
UOM:
1 * 5 mg
New Product
Numéro de catalogue:
(PRSI30-235)
Fournisseur:
ProSci Inc.
Description:
RTN4 belongs to the family of reticulons. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. RTN4 is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates.This gene belongs to the family of reticulon encoding genes. Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The product of this gene is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Alternatively spliced transcript variants derived both from differential splicing and differential promoter usage and encoding different isoforms have been identified.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4793)
Fournisseur:
ProSci Inc.
Description:
ACVR1B Antibody: Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I and two type II receptors. ACVR1B, also known as activin receptor-like kinase 4 (ALK4), is a type I receptor for activin and plays major roles in cell differentiation, growth arrest and apoptosis. Like another type I activin receptor ACVR1C, ACVR1B can mediate signaling by ligands such as Nodal, Xnr1, GDF-1/3, activin B and activin AB. In Xenopus embryos, expression of a dominant-negative form of ACVR1B blocked all mesoderm-inducing ligands, while expression of a dominant negative ACVR1C only blocked Nodal and Xnr1 signaling, suggesting that the ACVR1B and ACVR1C possess distinct functions.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI76-795)
Fournisseur:
ProSci Inc.
Description:
The HMb1-1 monoclonal antibody specifically reacts with mouse/rat CD29, a 130 kDa molecule also known as integrin beta 1, GPIIa, and the VLA-beta chain. It is expressed broadly on endothelial cells, epithelial, leukocytes, and smooth muscle. CD29 forms the VLA 1-6 complexes through the non-covalent interaction with the alpha integrins of CD49 a-f. The HMb1-1 antibody is capable of inhibiting T cell proliferation and blocking cell adhesion.
UOM:
1 * 0,5 mg
New Product
Numéro de catalogue:
(PRSI76-025)
Fournisseur:
ProSci Inc.
Description:
The HM40-3 monoclonal antibody reacts with mouse CD40, a 48 kDa type I glycoprotein known as Bp50. CD40 is part of the TNFR family and expressed on a subset of T cells, B cells, dendritic cells, and macrophages. It has been shown to be involved in the protection of B cells from apoptosis, B cell differentiation, co-stimulation, and isotype class-switching. The HM40-3 antibody blocks the binding of CD40L (CD154) and stimulates B and dendritic cell proliferation.
UOM:
1 * 0,05 mg
New Product
Numéro de catalogue:
(AATB12624)
Fournisseur:
AAT BIOQUEST INC
Description:
6XHis Succinimidyl Ester is an excellent building block to make 6XHis conjugates for developing His tag detection probes and purification tools.
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(PRSI25-254)
Fournisseur:
ProSci Inc.
Description:
KCNJ12 is an inwardly rectifying K+ channel which may be blocked by divalent cations. This protein is thought to be one of multiple inwardly rectifying channels which contribute to the cardiac inward rectifier current (IK1). This gene is located within the Smith-Magenis syndrome region on chromosome 17. This gene encodes an inwardly rectifying K+ channel which may be blocked by divalent cations. This protein is thought to be one of multiple inwardly rectifying channels which contribute to the cardiac inward rectifier current (IK1). The gene is located within the Smith-Magenis syndrome region on chromosome 17. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
UOM:
1 * 50 µG
Numéro de catalogue:
(AATB21127)
Fournisseur:
AAT BIOQUEST INC
Description:
Rhod-4™ maleimide is an excellent building block that can be readily used to prepare a calcium-sensitive bioconjugate for monitoring calcium change spatially for a specific target.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI26-963)
Fournisseur:
ProSci Inc.
Description:
TMOD3 belongs to the tropomodulin family. It blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. This gene is a necessary element in receptor tyrosine kinase pathways, possibly as a tyrosine phosphorylation target. It is involved in regulation of RAF in the MAPK pathway and may also play a role in a MAPK-independent pathway.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI26-964)
Fournisseur:
ProSci Inc.
Description:
TMOD3 belongs to the tropomodulin family. It blocks the elongation and depolymerization of the actin filaments at the pointed end. The Tmod/TM complex contributes to the formation of the short actin protofilament, which in turn defines the geometry of the membrane skeleton. This gene is a necessary element in receptor tyrosine kinase pathways, possibly as a tyrosine phosphorylation target. It is involved in regulation of RAF in the MAPK pathway and may also play a role in a MAPK-independent pathway.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-123)
Fournisseur:
ProSci Inc.
Description:
DLL1 (Delta-like protein; Delta1) is essential for postnatal arteriogenesis and contributes to tumour progression. DLL1 is involved in differentiation and self-renewal of adipocyte stem cells. Blocks the differentiation of progenitor cells into the B cell lineage while promoting the emergence of a population of cells with the characteristics of a T cell/NK-cell precursor.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI3195P)
Fournisseur:
ProSci Inc.
Description:
Caspase-12 peptide is used for blocking the activity of the Caspase-12 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-070)
Fournisseur:
ProSci Inc.
Description:
The Notch ligand delta-like protein 1 (DLL1) is essential for postnatal arteriogenesis and contributes to tumour progression. DLL1 is involved in differentiation and self-renewal of adipocyte stem cells. Blocks the differentiation of progenitor cells into the B cell lineage while promoting the emergence of a population of cells with the characteristics of a T cell/NK-cell precursor.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI4979P)
Fournisseur:
ProSci Inc.
Description:
RNAse H2A peptide is used for blocking the activity of RNAse H2A antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4827P)
Fournisseur:
ProSci Inc.
Description:
Integrin alpha 4 peptide is used for blocking the activity of integrin alpha 4 antibody.
UOM:
1 * 50 µG
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