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Numéro de catalogue: (BOSSBS-11474R-A555)

Fournisseur:  Bioss
Description:   The repulsive guidance molecule (RGM) family of proteins are important in the guidance of growth cones of developing neurons. They are repulsive for a group of axons, those from the temporal half of the retina. RGM have been implicated in both axonal guidance and neural tube closure but as opposed to for ephrins, semaphorins, netrins and slits, no receptor mechanism for RGM activation has been defined. Dorsal root ganglion axons do not respond to RGM but neogenin (a netrin-binding protein which can function as an RGM receptor) expression can spur RGM responsiveness. The RGM proteins are attached to the membrane by a GPI-anchor. Two members of this family, RGMa and RGMb, are expressed in the nervous system. RGMc, also known as Hemojuvelin, is a part of the signaling pathway activating hepcidin and works together with hepcidin to restrict iron absorption in the gut. Defects in the gene encoding for RGMc causes the autosomal recessive disorder juvenile hemochromatosis (JH).
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-11475R-CY5)

Fournisseur:  Bioss
Description:   The repulsive guidance molecule (RGM) family of proteins are important in the guidance of growth cones of developing neurons. They are repulsive for a group of axons, those from the temporal half of the retina. RGM have been implicated in both axonal guidance and neural tube closure but as opposed to for ephrins, semaphorins, netrins and slits, no receptor mechanism for RGM activation has been defined. Dorsal root ganglion axons do not respond to RGM but neogenin (a netrin-binding protein which can function as an RGM receptor) expression can spur RGM responsiveness. The RGM proteins are attached to the membrane by a GPI-anchor. Two members of this family, RGMa and RGMb, are expressed in the nervous system. RGMc, also known as Hemojuvelin, is a part of the signaling pathway activating hepcidin and works together with hepcidin to restrict iron absorption in the gut. Defects in the gene encoding for RGMc causes the autosomal recessive disorder juvenile hemochromatosis (JH).
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-8548R-A647)

Fournisseur:  Bioss
Description:   The oligodendrocyte lineage-specific basic helix-loop-helix (OLIG) family of transcription factors include OLIG1-OLIG3, which differ in tissue expression. OLIG1 and OLIG2 are specifically expressed in nervous tissue as gene regulators of oligodendrogenesis. OLIG2 is more widely expressed in embryonic brain than OLIG1, while OLIG3 is primarily expressed in non-neural tissues. OLIG1 and OLIG2 interact with the Nkx-2.2 homeodomain protein, which is responsible for directing ventral neuronal patterning in response to graded Sonic hedgehog signaling in the embryonic neural tube. These interactions between OLIG proteins and Nkx-2.2 appear to promote the formation of alternate cell types by inhibiting V3 interneuron development. OLIG1 and OLIG2 are abundantly expressed in oligodendroglioma and nearly absent in astrocytomas. Therefore, OLIG proteins are candidates for molecular markers of human glial brain tumors, which are the most common primary malignancies of the human brain.
UOM:  1 * 100 µl
Fournisseur:  BOETTGER, PAUL
Description:   PP, with green or yellow HDPE screw cap.
Fournisseur:  MURRAY, S & CO LTD
Description:   Neutral resistance glass with funnel top.

Fournisseur:  TESTO
Description:   Ces sondes Smart Probes sont destinées à être utilisées avec des smartphones et des tablettes. Les utilisateurs peuvent lire les mesures au moyen de l'application Smart Probes de Testo installée sur leur périphérique. L'application vous permet de lire à distance les mesures transmises par six sondes Smart Probes et de documenter/consigner facilement les résultats. Utilisées avec des tubes de Pitot (non inclus), elles peuvent servir à déterminer la vitesse de l'air et le débit volumique.
UOM:  1 * 1 ST
Fournisseur:  Portwest
Description:   This slim fit stretch trouser has all the features of a cargo style with the advantage of dynamic cotton stretch twill fabric. This stretch fabric gives the ultimate in comfort and freedom of movement. Features include multiple utility pockets and a concealed hook and bar waist fastening. With twin stitching throughout and bar-tacking at all stress points, this trouser is highly durable.
Fournisseur:  Thermo Scientific
Description:   Idéales pour les traitements de routine, ces centrifugeuses combinent des capacités exceptionnelles et un rapport qualité-prix à la pointe du marché, notamment une productivité et un débit inégalés, ainsi qu'une ergonomie exceptionnelle.
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Fournisseur:  Portwest
Description:   The WX3 Eco Polo Shirt is sustainable workwear from Portwest. Designed with an active fit, this polo uses premium bamboo and recycled polyester that will keep you cool, dry and comfortable all day long.
Numéro de catalogue: (BOSSBS-5863R)

Fournisseur:  Bioss
Description:   Expressed in epithelial cells of the colon, fallopian tube, skin, breast, prostate, epididymis, liver, pancreatic islets and bile ducts, as well as by vascular endothelial cells, smooth muscle cells, fibroblasts, cortical and ganglionic neurons and cardiac myocytes. Also expressed by malignant epithelial cells in colon cancer, as well as breast, prostate, renal and skin tumors. Expression is significantly reduced in colon cancer compared to normal colon.
UOM:  1 * 100 µl
Fournisseur:  Biotium
Description:   TIMP3 (tissue inhibitor of metalloproteinases 3), along with family members TIMP1, TIMP2, and TIMP4, are inhibitors of the matrix metalloproteinases (MMPs), a group of peptidases involved in degradation of the extracellular matrix (ECM). An imbalance between MMPs and the associated TIMPs may play a significant role in the invasive phenotype of malignant tumors. TIMP s inhibit the proteolytic invasiveness of tumor cells and normal placental trophoblast cells. TIMP-3 may be involved in regulating trophoblastic invasion of the uterus as well as in regulating remodeling of the extracellular matrix during the folding of epithelia, and in the formation, branching and expansion of epithelial tubes.

Fournisseur:  Bioss
Description:   Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP2 beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.
UOM:  1 * 100 µl
Fournisseur:  Bioss
Description:   Sequence-specific DNA-binding protein that interacts with inducible viral and cellular enhancer elements to regulate transcription of selected genes. AP2 factors bind to the consensus sequence 5'-GCCNNNGGC-3' and activate genes involved in a large spectrum of important biological functions including proper eye, face, body wall, limbs and neural tube development. They also suppress a number of genes including MCAM/MUC18, C/EBP alpha and MYC. AP2 beta appears to be required for normal face and limb development and for proper terminal differentiation and function of renal tubular epithelia.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-1544R-A647)

Fournisseur:  Bioss
Description:   Intercellular signal essential for a variety of patterning events during development: signal produced by the notochord that induces ventral cell fate in the neural tube and somites, and the polarizing signal for patterning of the anterior-posterior axis of the developing limb bud. Displays both floor plate- and motor neuron-inducing activity. The threshold concentration of N-product required for motor neuron induction is 5-fold lower than that required for floor plate induction. Activates the transcription of target genes by interacting with its receptor PTCH1 to prevent normal inhibition by PTCH1 on the constitutive signaling activity of SMO (By similarity).
UOM:  1 * 100 µl
Numéro de catalogue: (DELT4096.2N)

Fournisseur:  DELTALAB
Description:   Made of PP.
UOM:  1 * 125 ST
Fournisseur:  Bohlender
Description:   Vacuum filters with multi-stage hose connector with integrated lock screw for connecting vacuum tubing with Int.Ø 6 mm or 8 mm. The filters are produced without plasticisers and have an almost universal chemical resistance.
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Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'call est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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