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Numéro de catalogue: (BOSSBS-9410R-CY7)

Fournisseur:  Bioss
Description:   The protein encoded by this gene is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-0772R-CY5)

Fournisseur:  Bioss
Description:   Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-0772R-CY7)

Fournisseur:  Bioss
Description:   Organizes filamentous actin into bundles with a minimum of 4.1:1 actin/fascin ratio. Plays a role in the organization of actin filament bundles and the formation of microspikes, membrane ruffles, and stress fibers. Important for the formation of a diverse set of cell protrusions, such as filopodia, and for cell motility and migration.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   TSPAN5 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterised by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-3637R-CY3)

Fournisseur:  Bioss
Description:   TSPAN5 is a member of the transmembrane 4 superfamily, also known as the tetraspanin family. Most of these members are cell-surface proteins that are characterized by the presence of four hydrophobic domains. The proteins mediate signal transduction events that play a role in the regulation of cell development, activation, growth and motility.
UOM:  1 * 100 µl

Fournisseur:  VWR Chemicals
Description:   A fluorescent stain for nucleic acids in agarose and polyacrylamide gels. Concentrations of 120 ?M will detect DNA at levels of 25-50 ng per band. Also used for to localize nucleic acids in a variety of cell types
UOM:  1 * 50 g
Fournisseur:  Bioss
Description:   Inhibits cell proliferation by negative regulation of the G1/S transition. Mediates cell death which is not of the classical apoptotic type and regulates expression of components of the plasminogen pathway.
UOM:  1 * 100 µl
Fournisseur:  Biotium
Description:   This MAb recognizes a 21 kDa protein, identified as the p21WAF1 tumor suppressor protein. This MAb is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdk's and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma).

Fournisseur:  Biotium
Description:   This MAb recognizes a 21 kDa protein, identified as the p21WAF1 tumor suppressor protein. This MAb is highly specific to p21 and shows no cross-reaction with other closely related mitotic inhibitors. p21WAF1 is a specific inhibitor of cdk's and a tumor suppressor involved in the pathogenesis of a variety of malignancies. The expression of this gene acts as an inhibitor of the cell cycle during G1 phase and is tightly controlled by the tumor suppressor protein p53. Its expression is induced by the wild type, but not mutant, p53 suppressor protein. Normal cells generally display a rather intense nuclear p21 expression. Loss of p21 expression has been reported in many carcinomas (gastric carcinoma, non-small cell lung carcinoma, thyroid carcinoma).
UOM:  1 * 50 µl
Numéro de catalogue: (BOSSBS-7816R-A750)

Fournisseur:  Bioss
Description:   NSP type 5 alpha 3 alpha is a novel structure protein belonging to the cytospin-A family, that may play a role in nuclear function during cell division. It is also highly expressed in certain tumor cell lines, suggesting that it may serve as a good tumor marker. It was was cloned as part of a chromosomal translocation involving PDGFRB in a case of juvenile myelomonocytic leukemia.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-1595R-A750)

Fournisseur:  Bioss
Description:   spindle microtubules. The checkpoint works by inhibiting the activity of the anaphase promoting complex, thereby preventing the degradation of several cell cycle regulators. Like other spindle checkpoint mutants, MAD1 loss-of-function mutants are sensitive to benomyl and cannot delay cell division in response to spindle depolymerization. Mad1p becomes hyperphosphorylated upon spindle depolymerization.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-7925R-CY3)

Fournisseur:  Bioss
Description:   Rapidly and transiently inhibited by phosphorylation following the generation of DNA double-stranded breaks during S-phase. This is cell cycle checkpoint and ATM-pathway dependent and appears to regulate processes involved in chromatin assembly.Tissue specificity: Widely expressed. Present in fetal placenta, liver, kidney, pancreas, heart and skeletal muscle. Also found in adult cell lines.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-0582R-A350)

Fournisseur:  Bioss
Description:   This is one of two genes encoding similar enzymes that catalyze the conversion of arachinodate to prostaglandin. The encoded protein regulates angiogenesis in endothelial cells, and is inhibited by nonsteroidal anti-inflammatory drugs such as aspirin. The protein may promote cell proliferation during tumor progression. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2012].
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-7683R-A680)

Fournisseur:  Bioss
Description:   Activates transcription of CYP11A1. Interaction with CREBBP and EP300 results in a synergistic transcriptional activation of CYP11A1.Tissue specificity:Highest expression was seen in thymus, testis and adrenal cortex, expressed also in the adrenal medulla, thyroid, and stomach. Highly expressed in steroidogenic JEG-3 and MCF-7 cells, low expression was seen in non-steroidogenic HepG2 and HK293 cells.
UOM:  1 * 100 µl

Fournisseur:  Bioss
Description:   Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory.
UOM:  1 * 100 µl
Numéro de catalogue: (BOSSBS-6981R-CY7)

Fournisseur:  Bioss
Description:   Mediates the exchange of chloride ions against protons. Functions as antiporter and contributes to the acidification of the endosome and synaptic vesicle lumen, and may thereby affect vesicle trafficking and exocytosis. May play an important role in neuronal cell function through regulation of membrane excitability by protein kinase C. It could help neuronal cells to establish short-term memory.
UOM:  1 * 100 µl
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