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masterflex+pinch+clamp
Numéro de catalogue:
(BOSSBS-3804R-FITC)
Fournisseur:
Bioss
Description:
Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. When bound, MutS alpha bends the DNA helix and shields approximately 20 base pairs, and recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone. This transition is crucial for mismatch repair. MutS alpha may also play a role in DNA homologous recombination repair. Recruited on chromatin in G1 and early S phase via its PWWP domain that specifically binds trimethylated 'Lys-36' of histone H3 (H3K36me3): early recruitment to chromatin to be replicated allowing a quick identification of mismatch repair to initiate the DNA mismatch repair reaction.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0758R-HRP)
Fournisseur:
Bioss
Description:
Component of the post-replicative DNA mismatch repair system (MMR). Forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. When bound, heterodimers bend the DNA helix and shields approximately 20 base pairs. MutS alpha recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. MutS beta recognizes larger insertion-deletion loops up to 13 nucleotides long. After mismatch binding, MutS alpha or beta forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone. This transition is crucial for mismatch repair. MutS alpha may also play a role in DNA homologous recombination repair. In melanocytes may modulate both UV-B-induced cell cycle regulation and apoptosis.
UOM:
1 * 100 µl
Numéro de catalogue:
(WITG8.430.000)
Fournisseur:
WITEG LABORTECHNIK GMBH
Description:
These universal three-pronged clamps are made of laquered aluminium, with nickel plated brass screws.
UOM:
1 * 1 ST
Fournisseur:
BURKLE
Description:
Échantillonneur pour les poudres en acier inoxydable. L'entrée conique permet la collecte d'échantillons de différentes tailles jusqu'à 50 ml environ. Fabriqué sans bord, rainure ou crevasse pour un nettoyage facile. L'échantillon est prélevé directement dans le sac de prélèvement, est maintenu en place avec la pince fournie. Ø du trou StickProof 25 mm ; longueur de chambre 120 mm. Sacs d'échantillonnage : 170×120 mm pour 400 ml.
Numéro de catalogue:
(FSCI18056-14)
Fournisseur:
FINE SCIENCE TOOLS
Description:
Pinces, Clamps, Acier inoxydable, 140 mm
UOM:
1 * 1 Pce
 Il s'agit d'un élément MarketSource. Des frais supplémentaires peuvent s'appliquer.
Numéro de catalogue:
(BOCH5630)
Fournisseur:
BOCHEM
Description:
Burette clamps made of chromium plated steel.
UOM:
1 * 1 ST
Numéro de catalogue:
(MFLX75506-70)
Fournisseur:
Avantor Fluid Handling
Description:
Two-stage design gives superior output pressures.
UOM:
1 * 1 ST
Fournisseur:
Avantor Fluid Handling
Description:
Easily remove tastes, odors, chlorine, and sediment.
Fournisseur:
Avantor Fluid Handling
Description:
Accurate volumetric dispensing of 4 microliters to 250 microliters.
Numéro de catalogue:
(BOSSBS-3804R)
Fournisseur:
Bioss
Description:
Component of the post-replicative DNA mismatch repair system (MMR). Heterodimerizes with MSH2 to form MutS alpha, which binds to DNA mismatches thereby initiating DNA repair. When bound, MutS alpha bends the DNA helix and shields approximately 20 base pairs, and recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. After mismatch binding, forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone. This transition is crucial for mismatch repair. MutS alpha may also play a role in DNA homologous recombination repair. Recruited on chromatin in G1 and early S phase via its PWWP domain that specifically binds trimethylated 'Lys-36' of histone H3 (H3K36me3): early recruitment to chromatin to be replicated allowing a quick identification of mismatch repair to initiate the DNA mismatch repair reaction.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0758R-FITC)
Fournisseur:
Bioss
Description:
Component of the post-replicative DNA mismatch repair system (MMR). Forms two different heterodimers: MutS alpha (MSH2-MSH6 heterodimer) and MutS beta (MSH2-MSH3 heterodimer) which binds to DNA mismatches thereby initiating DNA repair. When bound, heterodimers bend the DNA helix and shields approximately 20 base pairs. MutS alpha recognizes single base mismatches and dinucleotide insertion-deletion loops (IDL) in the DNA. MutS beta recognizes larger insertion-deletion loops up to 13 nucleotides long. After mismatch binding, MutS alpha or beta forms a ternary complex with the MutL alpha heterodimer, which is thought to be responsible for directing the downstream MMR events, including strand discrimination, excision, and resynthesis. ATP binding and hydrolysis play a pivotal role in mismatch repair functions. The ATPase activity associated with MutS alpha regulates binding similar to a molecular switch: mismatched DNA provokes ADP-->ATP exchange, resulting in a discernible conformational transition that converts MutS alpha into a sliding clamp capable of hydrolysis-independent diffusion along the DNA backbone. This transition is crucial for mismatch repair. MutS alpha may also play a role in DNA homologous recombination repair. In melanocytes may modulate both UV-B-induced cell cycle regulation and apoptosis.
UOM:
1 * 100 µl
Fournisseur:
Avantor Fluid Handling
Description:
Polypropylene fiber medium is thermally bonded to a rigid core for added durability.
Fournisseur:
Sartorius
Description:
Tête de pompe à chargement facile Masterflex - taille 15 pour Vivaflow® 200, Pour: Modular tangential flow systems, Vivaflow®
Fournisseur:
Avantor Fluid Handling
Description:
No clog or wear—contain no moving parts.
Fournisseur:
Avantor Fluid Handling
Description:
Meets the demands of various industries.
Fournisseur:
Avantor Fluid Handling
Description:
Get faster performance with miniature coil design.
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 est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'
est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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