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mycoplasma+detection
Numéro de catalogue:
(PRSI28-164)
Fournisseur:
ProSci Inc.
Description:
The PAX5 gene is a member of the paired box (PAX) family of transcription factors. The central feature of this gene family is a novel, highly conserved DNA-binding motif, known as the paired box. The PAX proteins are important regulators in early development, and alterations in the expression of their genes are thought to contribute to neoplastic transformation. The PAX5 gene encodes the B-cell lineage specific activator protein (BSAP) that is expressed at early, but not late stages of B-cell differentiation. Its expression has also been detected in developing CNS and testis, therefore, PAX5 gene product may not only play an important role in B-cell differentiation, but also in neural development and spermatogenesis.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7189)
Fournisseur:
ProSci Inc.
Description:
VTCN1 Antibody: T cell immunity plays a critical role in host immune surveillance of tumour cell growth and metastatic spread. VTCN1, also known as B7-H4, is a member of the B7 family of immune regulatory molecules. Expressed primarily on the membrane of lymphoid cells, VTCN1 is an immunoinhibitory protein that interacts with receptors on the surface of T lymphocytes, thus mediating cellular and humoral immune responses. Overexpression of VTCN1 is associated with certain malignancies, including ovarian and breast cancer, which may be a mechanism by which tumour cells suppress T cell immunity and facilitate tumour progression. VTCN1 may thus be a useful biomarker for the early detection of ovarian cancer.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI32-237)
Fournisseur:
ProSci Inc.
Description:
ZAP70(zeta-chain associated protein kinase), a 70 kDa member of the SYK tyrosine kinase family, plays a central role in lymphocyte activation and development, and is implicated in several immune disorders. Zap70 controls TCR(T-cell antigen receptor)-linked signal transduction pathways. Its key role in thymocytes development and mature T lymphocytes activation has been illustrated by the characterization of several human immunodeficiencies presenting with mutations in the zap-70 gene. ZAP-70 is also expressed in several types of B-cell neoplasm and is easily detected by immunohistochemistry, providing a useful prognostic marker in patients with chronic lymphocytic leukaemia.
UOM:
1 * 1 EA
Numéro de catalogue:
(BSBTPA2297)
Fournisseur:
BosterBio
Description:
Rabbit IgG polyclonal antibody for Potassium voltage-gated channel subfamily A member 4(KCNA4) detection. Tested with WB in Human, Mouse, Rat.
UOM:
1 * 1 EA
Fournisseur:
Shenandoah Biotechnology
Description:
Basic fibroblast growth factor (FGF-basic), also known as FGF-2, is expressed by endothelial cells and is a mediator of angiogenesis. FGF-basic also has cardioprotective functions during heart injury. FGF-basic is a critical component for embryonic stem cell culture systems and is necessary for maintaining cells in an undifferentiated state. Recombinant FGF-basic 154 is the full length FGF-basic protein encoded by the human FGF-2 gene. FGF-basic 154 is the most popular tissue culture product at Shenandoah Biotechnology, Inc. There are no detectable differences in biological activity between FGF-basic 154 and the truncated FGF-basic 147 proteins.
Numéro de catalogue:
(BSBTPB9023)
Fournisseur:
BosterBio
Description:
Polyclonal antibody for PARC/CCL18 detection. Host: Rabbit.Size: 100μg/vial. Tested applications: ELISA. Reactive species: Human. PARC/CCL18 information: Molecular Weight: 9849 MW; Subcellular Localization: Secreted; Tissue Specificity: Expressed at high levels in lung, lymph nodes, placenta, bone marrow, dendritic cells present in germinal centers and T-cell areas of secondary lymphoid organs and macrophages derived from peripheral blood monocytes. Not expressed by peripheral blood monocytes and a monocyte-to-macrophage differentiation is a prerequisite for expression. Expressed in synovial fluids from patients with rheumatoid and septic arthritis and in ovarian carcinoma ascitic fluid.
UOM:
1 * 1 EA
Numéro de catalogue:
(BSBTMA1009)
Fournisseur:
BosterBio
Description:
Mouse IgG monoclonal antibody for Caldesmon (smooth), caldesmon 1 (CALD1) detection. Tested with WB, IHC-F in Human;mouse;rat. No cross reactivity with other proteins.
UOM:
1 * 0,1 mg
Numéro de catalogue:
(PRSI3953)
Fournisseur:
ProSci Inc.
Description:
RIG-1 Antibody: The innate immune system detects viral infection by recognizing various viral components and triggers antiviral responses. Like the toll-like receptor 3 (TLR3), the cytoplasmic helicase retinoic acid inducible gene protein 1 (RIG-1) recognizes double-stranded (ds) RNA, a molecular pattern associated with viral infection. Unlike TLR3 however, RIG-1 activates the kinases TBK1 and IKK epsilon through the adaptor protein IPS-1. These kinases then phosphorylate the transcription factors IRF-3 and IRF-7 which are essential for the expression of type-I interferons. RIG-1 is required for the production of interferons in response to RNA viruses including paramyxoviruses, influenza virus, and Japanese encephalitis virus.
UOM:
1 * 1 EA
Numéro de catalogue:
(BSBTPB9069)
Fournisseur:
BosterBio
Description:
Polyclonal antibody for GDNF detection. Host: Rabbit.Size: 100μg/vial. Tested applications: WB. Reactive species: Human. GDNF information: Molecular Weight: 23720 MW; Subcellular Localization: Secreted ; Tissue Specificity: In the brain, predominantly expressed in the striatum with highest levels in the caudate and lowest in the putamen. Isoform 2 is absent from most tissues except for low levels in intestine and kidney. Highest expression of isoform 3 is found in pancreatic islets. Isoform 5 is expressed at very low levels in putamen, nucleus accumbens, prefrontal cortex, amygdala, hypothalamus and intestine. Isoform 3 is up-regulated in the middle temporal gyrus of Alzheimer disease patients while isoform 2 shows no change.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI29-392)
Fournisseur:
ProSci Inc.
Description:
APOBEC2 belongs to the cytidine and deoxycytidylate deaminase family. It is probable C to U editing enzyme whose physiological substrate is not yet known. It does not display detectable apoB mRNA editing and has a low intrinsic cytidine deaminase activity.
UOM:
1 * 1 EA
Numéro de catalogue:
(BSBTPB9469)
Fournisseur:
BosterBio
Description:
Rabbit IgG polyclonal antibody for Advanced glycosylation end product-specific receptor (AGER) detection. Tested with WB, IHC-P in Human;Mouse;Rat.
UOM:
1 * 1 EA
Numéro de catalogue:
(BSBTPA2111-1)
Fournisseur:
BosterBio
Description:
Rabbit IgG polyclonal antibody for Nuclear factor NF-kappa-B p105 subunit(NFKB1) detection. Tested with WB in Human, Mouse, Rat.
UOM:
1 * 1 EA
Fournisseur:
AAT BIOQUEST INC
Description:
Anti-human secondary antibodies have well-characterised specificity for human immunoglobulins and are useful in the detection, sorting or purification of its specified target.
Fournisseur:
AAT BIOQUEST INC
Description:
Anti-human secondary antibodies have well-characterised specificity for human immunoglobulins and are useful in the detection, sorting or purification of its specified target.
Numéro de catalogue:
(PRSI92-134)
Fournisseur:
ProSci Inc.
Description:
Caspase-10 (CASP10) is a 521 amino acid protein member of the Cysteine-Aspartic Acid Protease (Caspase) family. CASP10 contains two DED (Death Effector) domains and is detectable in most tissues. CASP10 cleavage by Granzyme B and autocatalytic activity generate the two active subunits: Caspase-10 subunit p23/17, Caspase-10 subunit p12. Caspases are a family of cytosolic aspartate-specific cysteine proteases involved in the execution-phase of cell apoptosis, the initiation and execution. Human caspases can be subdivided into three functional groups: cytokine activation (caspase-1, -4, -5, and -13), apoptosis initiation (caspase-2, -8, -9, -and -10), and apoptosis execution (caspase-3, -6, and -7). CASP10 cleaves and activates caspases 3 and 7, but itself is processed by caspase 8. Defects in CASP10 are associated with apoptosis defects seen in type II autoimmune lymphoproliferative syndrome.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI76-098)
Fournisseur:
ProSci Inc.
Description:
The N418 monoclonal antibody specifically reacts with the integrin alpha x chain of the mouse CD11c, which is expressed on dendritic cells, CD4-/CD8+ intestinal intraepithelial lymphocytes (IEL) and some activated T lymphocytes. Low levels of CD11c were detected on mouse splenic natural killer cells and on the monocyte/macrophage lineage cells.CD11c expression is upregulated on IEL and T lymphocytes after activation. It binds to CD54, fibrinogen and iC3b and influences the leukocyte adhesive interactions. The N418 antibody binds to CD11c on splenic dendritic cells of the mouse in the T-dependent areas. It also contributes to the binding of iC3b.
UOM:
1 * 0,025 mg
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