Anticorps
Numéro de catalogue:
(BOSSBS-3654R-CY7)
Fournisseur:
Bioss
Description:
Low affinity receptor for N-formyl-methionyl peptides, which are powerful neutrophils chemotactic factors. Binding of FMLP to the receptor causes activation of neutrophils. This response is mediated via a G-protein that activates a phosphatidylinositol-calcium second messenger system. The activation of LXA4R could result in an anti-inflammatory outcome counteracting the actions of proinflammatory signals such as LTB4 (leukotriene B4).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3103R-A750)
Fournisseur:
Bioss
Description:
The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukaemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3103R-CY5.5)
Fournisseur:
Bioss
Description:
The protein encoded by this gene is constitutively tyrosine phosphorylated in hematopoietic progenitors isolated from chronic myelogenous leukemia (CML) patients in the chronic phase. It may be a critical substrate for p210(bcr/abl), a chimeric protein whose presence is associated with CML. This encoded protein binds p120 (RasGAP) from CML cells. [provided by RefSeq, Jul 2008]
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-15146R-A350)
Fournisseur:
Bioss
Description:
C2orf15
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13492R-A647)
Fournisseur:
Bioss
Description:
The Golgi apparatus is a highly complex organelle comprised of a stack of cisternal membranes on the secretory pathway from the ER to the cell surface. The structure is maintained by an exoskeleton or Golgi matrix constructed from a family of coiled-coil protein, the golgins and other peripheral membrane components such as GRASP55 and GRASP65 (1). GRASP55 (Golgi reassembly stacking protien or p59) is a component of the Golgi stacking machinery. GRASP55 is highly homologous to GRASP65 and contains two PDZ domains. GRASP55 is myristoylated and palmitoylated. Unlike GRASP65, GRASP55 does not have detectable binding with the vesicle docking protein GM130 and is located on the medial-Golgi rather than cis-Golgi. Both GRASP55 and GRASP65 function in the stacking of Golgi Cisternae (2,3). The novel coiled-coil protein golgin 45 interacts with GRASP55 and the GTP form of Rab 2, suggesting that GRASP55 and golgin 45 form a Rab 2 effector complex on medial-Golgi essential for normal protein transport and Golgi structure (4). ERK2 directly phosphorylates GRASP55, which is phosphorylated in mitotic cells, suggesting that mitogen-activated protein kinase kinase (MKK)/ERK pathway phosphorylates the Golgi during mitosis (5).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13268R-A680)
Fournisseur:
Bioss
Description:
Galactose Mutarotase is a member of the aldose epimerase family and is involved in hexose metabolism. Through its catalytic activity, Galactose Mutarotase converts beta-aldose to alpha-aldose on several sugars, including D-glucose, L-arabinose and D-xylose. Found in the cytoplasm of most cells, Galactose Mutarotase plays a key role in galactose metabolism by catalyzing the conversion of beta-D-galactose to alpha-D-galactose. The enzyme contains two residues, Glu 304 and His 170, that are critical for catalysis, as well as His 96 and Asp 243, which are important for proper substrate recognition by the active site. No known diseases have been associated with mutations in the Galactose Mutarotase gene, although inhibition of Galactose Mutarotase activity could potentially be associated with a build-up of unmetabolized sugars during metabolism.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3205R-CY7)
Fournisseur:
Bioss
Description:
Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Promotes phosphorylation of SHC1, STAT1 and PTPN11/SHP2. In the nucleus, enhances RPS6KA1 and CREB1 activity and contributes to the regulation of transcription. FGFR1 signaling is down-regulated by IL17RD/SEF, and by FGFR1 ubiquitination, internalization and degradation.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11013R-CY7)
Fournisseur:
Bioss
Description:
ILDR1 is a putative membrane receptor. It belongs to the immunoglobulin superfamily, LISCH7 family. It is mainly expressed in prostate and to a lower extent in testis, pancreas, kidney, heart and liver.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7054R-A350)
Fournisseur:
Bioss
Description:
Condensing enzyme that catalyzes the synthesis of monounsaturated and of polyunsaturated very long chain fatty acids Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA.Tissue specificity: Ubiquitous. Highly expressed in the adrenal gland and testis. Weekly expressed in prostate, lung and brain.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7053R-A750)
Fournisseur:
Bioss
Description:
Condensing enzyme that catalyzes the synthesis of polyunsaturated very long chain fatty acid (C20- and C22-PUFA). Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C20:4(n-6) acyl-CoA.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7054R-CY3)
Fournisseur:
Bioss
Description:
Condensing enzyme that catalyzes the synthesis of monounsaturated and of polyunsaturated very long chain fatty acids Acts specifically toward polyunsaturated acyl-CoA with the higher activity toward C18:3(n-6) acyl-CoA.Tissue specificity: Ubiquitous. Highly expressed in the adrenal gland and testis. Weekly expressed in prostate, lung and brain.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-15120R-FITC)
Fournisseur:
Bioss
Description:
Representing about 2% of human DNA, chromosome 20 consists of approximately 63 million bases and 600 genes. Chromosome 20 contains a region with numerous genes expressed in the epididymis, which are thought important for seminal production, and some viewed as potential targets for male contraception. The PRNP gene encoding the prion protein associated with spongiform encephalopathies, like Creutzfeldt-Jakob disease, is found on chromosome 20. Amyotrophic lateral sclerosis, spinal muscular atrophy, ring chromosome 20 epilepsy syndrome and Alagille syndrome are also associated with chromosome 20. The C20orf96 gene product has been provisionally designated C20orf96 pending further characterization.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3959R-A350)
Fournisseur:
Bioss
Description:
Core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone (By similarity).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11387R-FITC)
Fournisseur:
Bioss
Description:
AADACL4 is a 407 amino acid single-pass type II membrane protein belonging to the 'GDXG' lipolytic enzyme family. Integral to the cell membrane, AADACL4 participates in carboxylesterase and hydrolase activities and is encoded by a gene that maps to human chromosome 1p36.22. Chromosome 1, the largest human chromosome, makes up 8% of the human genome and contains about 260 million base pairs, which encode 3,000 genes. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11387R-A488)
Fournisseur:
Bioss
Description:
AADACL4 is a 407 amino acid single-pass type II membrane protein belonging to the 'GDXG' lipolytic enzyme family. Integral to the cell membrane, AADACL4 participates in carboxylesterase and hydrolase activities and is encoded by a gene that maps to human chromosome 1p36.22. Chromosome 1, the largest human chromosome, makes up 8% of the human genome and contains about 260 million base pairs, which encode 3,000 genes. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3958R-HRP)
Fournisseur:
Bioss
Description:
Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.
UOM:
1 * 100 µl
Appel de prix
Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l' est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l' est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
Ces articles ne peuvent être ajoutés au Panier. Veuillez contacter votre service client ou envoyer un e-mail à vwr.be@vwr.com
Une documentation supplémentaire peut être nécessaire pour l'achat de cet article. Un représentant de VWR vous contactera si nécessaire.
Ce produit a été bloqué par votre organisation. Contacter votre service d'achat pour plus d'informations.
Le produit original n'est plus disponible. Le remplacement représenté est disponible
Les produits marqués de ce symbole ne seront bientôt plus disponibles - vente jusqu'à épuisement de stock. Des alternatives peuvent être disponibles en recherchant le code article VWR indiqué ci-dessus. Si vous avez besoin d'une assistance supplémentaire, veuillez contacter notre Service Clientèle au 016 385 011.
|
|||||||||