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Anticorps
Numéro de catalogue:
(USBI037113-AP)
Fournisseur:
US Biological
Description:
Anti-IRX2 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
UOM:
1 * 200 µl
Numéro de catalogue:
(USBI037114-APC)
Fournisseur:
US Biological
Description:
Anti-IRX3 Rabbit Polyclonal Antibody (APC (Allophycocyanin))
UOM:
1 * 200 µl
Numéro de catalogue:
(USBI167527)
Fournisseur:
US Biological
Description:
Anti-TNNI3 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(USBI167525)
Fournisseur:
US Biological
Description:
Anti-TNNI2 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(USBI167533)
Fournisseur:
US Biological
Description:
Anti-UBN1 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(USBI043272-PE)
Fournisseur:
US Biological
Description:
Anti-TRIX3 Rabbit Polyclonal Antibody (PE (Phycoerythrin))
UOM:
1 * 200 µl
Numéro de catalogue:
(BOSSBS-8719R)
Fournisseur:
Bioss
Description:
Leucine-rich protein (LRP130) is a cytoplasmic mRNA-binding protein likely to be involved in the processing of mitochondrial DNA transcripts. Defects in the LRPPRC gene that encodes LRP130 result in the French-Canadian type of Leigh syndrome, a severe neurological disorder characterized by lesions in the subcortical region of the brain. LRP130 also interacts with the low-affinity receptor for leukemia inhibitory factor to produce an intracelluar signal cascade.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5561R)
Fournisseur:
Bioss
Description:
Members of the protein kinase C (PKC) family function in many extracellular receptor-mediated signal transduction pathways. See PRKCA (MIM 176960) for further background information. The PRKCM gene encodes a cytosolic serine-threonine kinase that binds to the trans-Golgi network and regulates the fission of transport carriers specifically destined to the cell surface.[supplied by OMIM]
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8681R)
Fournisseur:
Bioss
Description:
Spermine synthase catalyzes the production of spermine from spermidine. Spermine, a polyamine ubiquitously present in most organisms, is essential for normal cell growth and differentiation. Because absence of spermine increases sensitivity of cells to anti-tumor agents, spermine synthase (and other polyamine biosynthesis) is an attractive target for anti-neoplastic therapy.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8691R)
Fournisseur:
Bioss
Description:
Voltage-gated K+ channels in the plasma membrane control the repolarization and the frequency of action potentials in neurons, muscles and other excitable cells. The KV gene family encodes more than 30 proteins that comprise the subunits of the K+ channels, and they vary in their gating and permeation properties, subcellular distribution and expression patterns. Functional KV channels assemble as tetramers consisting of pore-forming å subunits (KV), which include the KV1, KV2, KV3 and KV4 proteins, and accessory or KV-subunits that modify the gating properties of the coexpressed KV subunits. KV∫, also known as KCNAB1 (potassium voltage-gated channel, shaker-related subfamily, beta member 1), is a 419 amino acid accessory K+ channel protein that exists as three alternatively spliced isoforms and regulates the activity of the pore-forming å subunit. It is expressed in brain, with highest levels detected in caudate nucleus, hippocampus and thalamus.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8858R)
Fournisseur:
Bioss
Description:
Anti-EAST1 Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
Fournisseur:
Biotium
Description:
By immunohistochemistry, this antibodyspecifically recognizes a protein in melanocytes and melanomas. This MAb reacts with junctional and blue nevus cells and variably with fetal and neonatal melanocytes. Intradermal nevi, normal adult melanocytes, and non-melanocytic cells are negative. It does not stain tumor cells of epithelial, lymphoid, glial, or mesenchymal origin. Metastatic amelanotic melanoma can often be confused with a variety of poorly differentiated carcinomas, large cell lymphomas, and sarcomas using H & E stains alone. It is also difficult to differentiate melanoma from spindle cell carcinomas and various types of mesenchymal neoplasms. This MAb stains fetal and neonatal melanocytes, junctional and blue nevus cells, and malignant melanoma. This MAb also stains Angiomyolipoma (PEComa).
Fournisseur:
Biotium
Description:
The onset of angiogenesis is believed to be an early event in tumorigenesis and may facilitate tumor progression and metastasis. Several growth factors with angiogenic activity have been described. These include Fibroblast Growth Factor (FGF), Platelet Derived Growth Factor (PDGF), Vascular Endothelial Growth Factor (VEGF) and Placenta Growth Factor (PLGF). Placenta growth factor (PLGF) is a secreted protein primarily produced by placental trophoblasts but also expressed in other endothelial cells and tumors. There are three isoforms, PLGF-1, PLGF-2, and PLGF-3. PLGF-2 is expressed up until week 8 in the placenta; the placental tissues continuously express PLGF-1 and PLGF-3 but only PLGF-1 is found in colon and mammary carcinomas. PLGF acts to stimulate angiogenesis, endothelial growth and migration. PLGF is a powerful promoter of tumor growth and is upregulated in some cancers, and PLGF is thought to aid in atherosclerotic lesions and neovascular growth surrounding the lesion. Also, PLGF appears to aid aldosterone mediated atherosclerosis. Serum levels of PLGF in some cases are used as a potential biomarker for disease or genetic defect. Recent research indicates that PLGF levels are lower in mothers with Down syndrome fetuses. Evidence has suggested VEGF to be an obligatory component in PLGF signaling. While VEGF homodimers and VEGF/PLGF heterodimers function as potent mediators of mitogenic and chemotactic responses in endothelial cells, PLGF homodimers are effectual only at extremely high concentrations. Indeed, many of the physiological effects attributed to VEGF may actually be a result of VEGF/PLGF. VEGF and PLGF share a common receptor, Flt-1, and may also activate Flk-1/KDR.
Numéro de catalogue:
(BWRLBS1879)
Fournisseur:
Bioworld Technology
Description:
Synthetic peptide, corresponding to amino acids 101-150 of Human AIRE.
UOM:
1 * 1 EA
Numéro de catalogue:
(BWRLBS3336)
Fournisseur:
Bioworld Technology
Description:
Synthetic peptide, corresponding to amino acids 120-170 of Human NDUFA8.
UOM:
1 * 1 EA
Numéro de catalogue:
(BWRLBS3332)
Fournisseur:
Bioworld Technology
Description:
Synthetic peptide, corresponding to amino acids 380-430 of Human MNDA.
UOM:
1 * 1 EA
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