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Protéines et Peptides
Numéro de catalogue:
(PRSI6123P)
Fournisseur:
ProSci Inc.
Description:
ZBTB5 peptide is used for blocking the activity of ZBTB5 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-562)
Fournisseur:
ProSci Inc.
Description:
Dtk, also called Tyro3, belongs to the TAM receptor family of receptor protein tyrosine kinases (RPTKs) composed of three receptors Tyro3, Axl, and Mer. These receptors share a characteristic molecular structure of two immunoglobulin-like and two fibronectin type III repeats and have been best Characterised for their roles in immune regulation, fertility, thrombosis and phagocytosis. Gas6 and protein S have been identified as ligands for these receptors. Gas6 binding induces tyrosine phosphorylation and downstream signallling pathways that can lead to cell proliferation, migration, or the prevention of apoptosis. Tyro3 and Axl play important regulatory roles in a variety of tissues, including the central nervous, reproductive, immune, and vascular systems. Tyro3 is widely expressed during embryonic development and preferentially expressed during neurogenesis in the central nervous system.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-712)
Fournisseur:
ProSci Inc.
Description:
Human recombinant TFPI2 (from HEK293 cells)
UOM:
1 * 50 µG
Fournisseur:
SEQENS
Description:
SEQENS IVD manufactures Bovine Serum Albumin (BSA) derived from plasma, collected from healthy animals of French origin. This product is obtained by 'Heat Shock' method, which ensures higher purity and preserves BSA intrinsic properties.
Numéro de catalogue:
(PRSI7387P)
Fournisseur:
ProSci Inc.
Description:
18 amino acids near the carboxy terminus of human GOLGA5.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-243)
Fournisseur:
ProSci Inc.
Description:
Adiponectin is a secreted protein. It is synthesised exclusively by adipocytes and secreted into plasma. Adiponectin is an important adipokine that is involved in the control of fat metabolism and insulin sensitivity, with direct anti-diabetic, anti-atherogenic and anti-inflammatory activities. Adiponectin Stimulates AMPK phosphorylation and activates in the liver and the skeletal muscle, enhancing glucose utilisation and fatty-acid combustion. Adiponectin also antagonises TNF-alpha by negatively regulating its expression in various tissues such as liver and macrophages, and also by counteracting its effects. It inhibits endothelial NF-kappa-B signaling through a cAMP-dependent pathway. Adiponectin may play a role in cell growth, angiogenesis and tissue remodeling by binding and sequestering various growth factors with distinct binding affinities, depending on the type of complex: LMW, MMW or HMW.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-239)
Fournisseur:
ProSci Inc.
Description:
Tau proteins are proteins which contain four Tau/MAP repeats. They promote microtubule assembly and stability, and might be involved in the establishment and maintenance of neuronal polarity. They are abundant in neurons of the central nervous system and are less common elsewhere, but are also expressed at very low levels in CNS astrocytes and oligodendrocytes. The tau proteins are the product of alternative splicing from a single gene that in humans is designated MAPT. When tau proteins are defective, and no longer stabilize microtubules properly, they can result in several neurodegenerative disorders such as Alzheimer's disease, Pick's disease, frontotemporal dementia, cortico-basal degeneration and progressive supranuclear palsy.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-244)
Fournisseur:
ProSci Inc.
Description:
Macrophage migration inhibitory factor(MIF) is a secreted protein and belongs to the MIF family. MIF is an important regulator of innate immunity. The circulating MIF binds to CD74 on other immune cells to trigger an acute immune response. Hence MIF is classified as an inflammatory cytokine. Furthermore glucocorticoids also stimulate white blood cells to release MIF and hence MIF partially counter acts the inhibitory effects that glucocorticoids have on the immune system. Finally trauma activates the anterior pituitary gland to release MIF.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-231)
Fournisseur:
ProSci Inc.
Description:
UBE2D3 is an enzyme that belongs to the ubiquitin-conjugating enzyme family. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This enzyme functions in the ubiquitination of the tumour-suppressor protein p53, which is induced by an E3 ubiquitin-protein ligase.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3615P)
Fournisseur:
ProSci Inc.
Description:
APG7 peptide is used for blocking the activity of APG7 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3613P)
Fournisseur:
ProSci Inc.
Description:
Beclin-1 peptide is used for blocking the activity of Beclin-1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3605P)
Fournisseur:
ProSci Inc.
Description:
Bit1 peptide is used for blocking the activity of Bit1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-118)
Fournisseur:
ProSci Inc.
Description:
T-cell surface glycoprotein CD5 is also known as Lymphocyte antigen T1/Leu-1 and LEU1,which is phosphorylated on tyrosine residues by LYN,so CD5 can create binding sites for PTPN6/SHP-1.CD5 may act as a receptor in regulating T-cell proliferation. CD5 is expressed at various developmental and activation stages on human B cells.CD5 is a well established negative regulator of TCR and BCR signalling.CD5-positive cells may also prevent the emergence of autoimmunity by provision of cytokines such as IL-10. Development,selection and function of different B- and T-cell subsets or their preferential survival may be directly or indirectly dependent on different glycan structures associated with CD5 or CD5-like molecules.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI96-121)
Fournisseur:
ProSci Inc.
Description:
CD36 (Cluster of Differentiation 36) is also known as platelet membrane glycoprotein IV (GPIV), fatty acid translocase (FAT), thrombospondin receptor, collagen receptor, and scavenger receptor class B, member 3 (SRB3), is a member of the class B scavenger receptor family of cell surface proteins. The human CD36 gene encodes a single chain 472 amino acid residue protein containing both an N- and a C-terminal cytoplasmic tail and an extracellular loop.CD36 is found on platelets, erythrocytes, monocytes, differentiated adipocytes, mammary epithelial cells, spleen cells and some skin microdermal endothelial cells. CD36 is a multiligand pattern recognition receptor that interacts with a large number of structurally dissimilar ligands, including long chain fatty acid (LCFA), advanced glycation end products (AGE), thrombospondin-1, oxidized low-density lipoproteins (oxLDLs), high density lipoprotein (HDL), phosphatidylserine, apoptotic cells, beta-amyloid fibrils (fAβ), collagens I and IV, and Plasmodium falciparum infected erythrocytes. CD36 is required for the anti-angiogenic effects of thrombospondin1 In the corneal neovascularisation assay. On binding a ligand the protein and ligand are internalized. This internalisation is independent of macropinocytosis and occurs by an actin dependent mechanism requiring the activation Src-family kinases, JNK and Rho-family GTPases. CD36 ligands have also been shown to promote sterile inflammation through assembly of a Toll-like receptor 4 and 6 heterodimer.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI96-119)
Fournisseur:
ProSci Inc.
Description:
Cluster of Differentiation 86 (CD86) is also known as B-lymphocyte activation antigen B7-2, is a type I membrane protein that is a member of the immunoglobulin superfamily, and is constitutively expressed on interdigitating dendritic cells, Langerhans cells, peripheral blood dendritic cells, memory B cells, and germinal center B cells. Additionally, B72 is expressed at low levels on monocytes and can be upregulated through interferon γ. CD86 is the ligand for two different proteins on the T cell surface: CD28 (for autoregulation and intercellular association) and CTLA-4 (for attenuation of regulation and cellular disassociation). CD86 works in tandem with CD80 to prime T cells. Recent study has revealed that B7-2 promotes the generation of a mature APC repertoire and promotes APC function and survival. Furthermore, the B7 proteins are also involved in innate immune responses by activating NF-κB-signaling pathway in macrophages. CD86 thus is regarded as a promising candidate for immune therapy. CD86+ macrophages in Hodgkin lymphoma patients are an independent marker for potential nonresponse to firstline-therapy.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI6777P)
Fournisseur:
ProSci Inc.
Description:
YPEL4 peptide is used for blocking the activity of YPEL4 antibody.
UOM:
1 * 50 µG
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