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Protéines et Peptides
Numéro de catalogue:
(PRSI91-519)
Fournisseur:
ProSci Inc.
Description:
T-Cell Surface Glycoprotein CD8 beta Chain (CD8 Antigen) is a cell surface glycoprotein found on most cytotoxic T lymphocytes that mediates efficient cell-cell interactions within the immune system. CD8 Antigen, acting as a coreceptor, and the T-cell receptor on the T lymphocyte recognize antigens displayed by an antigen presenting cell (APC) in the context of class I MHC molecules. The functional coreceptor is either a homodimer composed of two alpha chains, or a heterodimer composed of one alpha and one beta chain. Both alpha and beta chains share significant homology to immunoglobulin variable light chains. Multiple alternatively spliced transcript variants encoding distinct membrane associated or secreted isoforms have been described. A pseudogene, also located on chromosome 2, has been identified.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-505)
Fournisseur:
ProSci Inc.
Description:
Apolipoprotein-D (ApoD) is an atypical apolipoprotein and, based on its primary structure, it also a member of the lipocalin family. ApoD is mainly associated with high density lipoproteins in human plasma. ApoD is expressed in numerous tissues having high levels of expression in spleen, testes and brain. ApoD plays a role in maintenance and repair within the central and peripheral nervous systems. ApoD occurs in the macromolecular complex with lecithin-cholesterol acyltransferase. It is a multi-ligand, multi-functional transporter and transports a ligand from 1 cell to another. ApoD is probably involved in the transport and binding of bilin, it appears to be able to transport a variety of ligands in a number of different contexts.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6561P)
Fournisseur:
ProSci Inc.
Description:
PRICKLE1 peptide is used for blocking the activity of PRICKLE1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7437P)
Fournisseur:
ProSci Inc.
Description:
18 amino acids near the carboxy terminus of ESR1.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-792)
Fournisseur:
ProSci Inc.
Description:
Pregnancy-specific beta-1-glycoprotein 9(PSG9) is a secreted protein and contains 3 Ig-like C2-type (immunoglobulin-like) domains, 1 Ig-like V-type (immunoglobulin-like) domain. It is a member of the PSG family, a group of closely related secreted glycoproteins that are highly expressed in fetal placental syncytiotrophoblast cells. The members of the PSG protein family all have a characteristic N-terminal domain that is homologous to the immunoglobulin variable region. PSGs become detectable in serum during the first two to three weeks of pregnancy and increase as the pregnancy progresses, eventually representing the most abundant fetal protein in the maternal blood at term. PSGs function to stimulate secretion of TH2-type cytokines from monocytes, and they may also modulate the maternal immune system during pregnancy, thereby protecting the semi-allotypic fetus from rejection. PSGs are commonly expressed in trophoblast tumors. Eleven human PSG proteins (PSG1-PSG11) have been described.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI1137P)
Fournisseur:
ProSci Inc.
Description:
GFR alpha 3 peptide is used for blocking the activity of GFR alpha 3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6107P)
Fournisseur:
ProSci Inc.
Description:
KLOTHO peptide is used for blocking the activity of KLOTHO antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-463)
Fournisseur:
ProSci Inc.
Description:
IL-1beta is produced by activated macrophages. IL-1beta stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1beta belongs to the IL-1 family of proteins that are involved in the inflammatory response. IL-1beta in most situations requires the inflammasome complex to be cleaved and secreted.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-464)
Fournisseur:
ProSci Inc.
Description:
Interleukin-2 (IL-2) is a 133 amino acid glycoprotein with one intramolecular disulfide bond and variable glycosylation. It is secreted by activated T cells and induces proliferation and maturation of activated T cells, natural killer cells, and lymphokine activated killer cells. IL-2 also stimulates proliferation of antibody-producing B cells, activates neutrophils, and induces mononuclear cells to secrete IFN-gamma and TNF-alpha and -beta. Moreover, studies have shown that IL-2 is required for activation-induced apoptosis, an important hemeostatic mechanism in the immune system, which is involved in the maintenance of peripheral tolerance to self-antigens.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6543P)
Fournisseur:
ProSci Inc.
Description:
RASSF6 peptide is used for blocking the activity of RASSF6 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI2301P)
Fournisseur:
ProSci Inc.
Description:
AIF peptide is used for blocking the activity of AIF antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI2321P)
Fournisseur:
ProSci Inc.
Description:
CIDE-B peptide is used for blocking the activity of CIDE-B antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-609)
Fournisseur:
ProSci Inc.
Description:
Programmed cell death protein 1 (PD-1) is also known as CD279 and PDCD1, is a type I membrane protein and is a member of the extended CD28/CTLA-4 family of T cell regulators. PDCD1 is expressed on the surface of activated T cells, B cells, macrophages, myeloid cells and a subset of thymocytes. PD-1 has two ligands, PD-L1 and PD-L2, which are members of the B7 family. PD-L1 is expressed on almost all murine tumor cell lines, including PA1 myeloma, P815 mastocytoma, and B16 melanoma upon treatment with IFN-γ. PD-L2 expression is more restricted and is expressed mainly by DCs and a few tumor lines. PD1 inhibits the T-cell proliferation and production of related cytokines including IL-1, IL-4, IL-10 and IFN-γ by suppressing the activation and transduction of PI3K/AKT pathway. In addition, coligation of PD1 inhibits BCR-mediating signal by dephosphorylating key signal transducer. In vitro, treatment of anti-CD3 stimulated T cells with PD-L1-Ig results in reduced T cell proliferation and IFN-γ secretion. Monoclonal antibodies targeting PD-1 that boost the immune system are being developed for the treatment of cancer.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI96-624)
Fournisseur:
ProSci Inc.
Description:
Human recombinant CD44 (from HEK293 cells)
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI7021P)
Fournisseur:
ProSci Inc.
Description:
PHLPP2 peptide is used for blocking the activity of PHLPP2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6991P)
Fournisseur:
ProSci Inc.
Description:
CASKIN1 peptide is used for blocking the activity of CASKIN1 antibody.
UOM:
1 * 50 µG
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