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Protéines et Peptides
Numéro de catalogue:
(PRSI92-117)
Fournisseur:
ProSci Inc.
Description:
Death Domain-Containing Protein CRADD (CRADD) is widely expressed in most tissues, with particularly high expression in the adult heart, testis, liver, skeletal muscle, fetal liver, and kidney. CRADD contains one CARD domain that mediates the interaction with caspase-2, and one death domain involved in the binding of RIP protein. CRADD functions as an apoptotic adaptor molecule specific for caspase-2 and FASL/TNF receptor-interacting protein RIP. CRADD induces cell apoptosis/cell death in numerous tissues. Defects in CRADD will result in mental retardation.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-624)
Fournisseur:
ProSci Inc.
Description:
Tumor necrosis factor receptor superfamily member 1B(TNFRSF1B) is expressed by the gene TNFRSF1B. The soluble form is produced from the membrane form by proteolytic processing. It can bind to TRAF2, and interacts with BMX. It can act as the receptor with high affinity for TNFSF2/TNF-alpha and approximately 5-fold lower affinity for homotrimeric TNFSF1/lymphotoxin-alpha. The TRAF1/TRAF2 complex recruits the apoptotic suppressors BIRC2 and BIRC3 to TNFRSF1B/TNFR2. This receptor mediates most of the metabolic effects of TNF-alpha.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7269P)
Fournisseur:
ProSci Inc.
Description:
17 amino acid peptide near the center of human PRKCDBP.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7263P)
Fournisseur:
ProSci Inc.
Description:
15 amino acids near the carboxy terminus of human KREMEN2.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-372)
Fournisseur:
ProSci Inc.
Description:
C1q R1 is also known as CD93, collectin receptor, and AA4 antigen, belongs to the Group XIV C-Type lectin family which play a role not only in cell–cell adhesion processes but also in host defence. All of them contain a C-type lectin domain, a series of epidermal growth factor like domains (EGF), a highly glycosylated mucin-like domain, a unique transmembrane domain and a short cytoplasmic tail. C1q R1 has also been identified as a hematopoietic stem cell marker.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-364)
Fournisseur:
ProSci Inc.
Description:
Cystatin-D is a protein that in humans is encoded by the CST5 gene. The cystatin superfamily encompasses proteins that contain multiple cystatin-like sequences. Some of the members are active cysteine protease inhibitors, while others have lost or perhaps never acquired this inhibitory activity. There are three inhibitory families in the superfamily, including the type 1 cystatins (stefins), type 2 cystatins and the kininogens. The type 2 cystatin proteins are a class of cysteine proteinase inhibitors found in a variety of human fluids and secretions. The cystatin locus on chromosome 20 contains the majority of the type 2 cystatin genes and pseudogenes. This gene is located in the cystatin locus and encodes a protein found in saliva and tears. The encoded protein may play a protective role against proteinases present in the oral cavity.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-093)
Fournisseur:
ProSci Inc.
Description:
Cluster of Differentiation 31 (CD31) is also known as Platelet endothelial cell adhesion molecule (PECAM-1), is a 130-kDa transmembrane glycoprotein expressed by endothelial cells, platelets, macrophages and Kupffer cells, granulocytes, T / NK cells, lymphocytes, megakaryocytes, osteoclasts, neutrophils, certain tumors, and is the only known member of the CAM family on platelets. CD31 is found on the surface of platelets, monocytes, neutrophils, and some types of T-cells, and makes up a large portion of endothelial cell intercellular junctions. The encoded protein is a member of the immunoglobulin superfamily and is likely involved in leukocyte migration, angiogenesis, and integrin activation. CD31 plays a key role in removing aged neutrophils from the body. CD31 mediates the homotypic or heterotypic cell adhesion by binding to itself or the leukocyte integrin αvβ3, and thus plays a role in neutrophil recruitment in inflammatory responses, transendothelial migration of leukocytes, as well as in cardiovascular development. In addition, it has been shown that CD31 expression is up-regulated by LPS stimulation, and might function as a feedback negative regulator of LPS inflammatory response in macrophages.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI7289P)
Fournisseur:
ProSci Inc.
Description:
15 amino acids near the carboxy terminus of human ERRF2.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3229P)
Fournisseur:
ProSci Inc.
Description:
ACE2 peptide is used for blocking the activity of ACE2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6917P)
Fournisseur:
ProSci Inc.
Description:
SARM peptide is used for blocking the activity of SARM antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6901P)
Fournisseur:
ProSci Inc.
Description:
STOX1 peptide is used for blocking the activity of STOX1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6915P)
Fournisseur:
ProSci Inc.
Description:
TET2 peptide is used for blocking the activity of TET2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6905P)
Fournisseur:
ProSci Inc.
Description:
ZBTB40 peptide is used for blocking the activity of ZBTB40 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4771P)
Fournisseur:
ProSci Inc.
Description:
GPVI peptide is used for blocking the activity of GPVI antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4783P)
Fournisseur:
ProSci Inc.
Description:
Integrin alpha 4 peptide is used for blocking the activity of integrin alpha 4 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-417)
Fournisseur:
ProSci Inc.
Description:
Phospholipase A2(PLA2G1B) is a secreted protein which belongs to the phospholipase A2 family. It catalyses the release of fatty acids from glycero-3-phosphocholines. It catalyses the calcium-dependent hydrolysis of the 2-acyl groups in 3-sn-phosphoglycerides. This releases glycerophospholipids and arachidonic acid that serve as the precursors of signal molecules. Sequences of pancreatic PLA2G1B enzymes from a variety of mammals have been reported. One striking feature of these enzymes is their close homology to venom phospholipases of snakes. Mice lacking in PLA2G1B are resistant to obesity and diabetes induced by feeding a diabetogenic high-fat/high-carbohydrate diet. Oral supplementation of a diabetogenic diet with the PLA2G1B inhibitor methyl indoxam effectively suppresses diet-induced obesity and diabetes. PLA2G1B inhibition may be a potentially effective oral therapeutic option for treatment of obesity and diabetes.
UOM:
1 * 50 µG
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