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Protéines et Peptides
Numéro de catalogue:
(PRSI91-050)
Fournisseur:
ProSci Inc.
Description:
Human Chemokine (C-C Motif) Ligand 8 (CCL8) is produced by human MG63 osteosarcoma cells. CCL8 shares 62% and 58% amino acid sequence identity with MCP-1 and MCP-3, respectively. All three MCP proteins are monocyte chemoattractants. CCL8 is chemotactic for and activates many different immune cells, including mast cells, eosinophils and basophils, which are implicated in allergic response, and monocytes, T cells, and NK cells that are involved in the inflammatory response. CCL8 elicits its effects by binding to several different cell surface receptors including CCR1, CCR2B and CCR5.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-046)
Fournisseur:
ProSci Inc.
Description:
Human Chemokine (C-X-C Motif) Ligand 14 (CXCL14) is constitutively expressed in certain normal tissues but is reduced or absent from many established tumor cell lines and human cancers. CXCL14 is known to be a chemoattractant for monocyte and dendritic cells. CXCL14 inhibits angiogenesis and exhibits antimicrobial activities. Mature human and mouse CXCL14 differ by only 2 amino acid residues.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI2383P)
Fournisseur:
ProSci Inc.
Description:
p53R2 peptide is used for blocking the activity of p53R2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI2347P)
Fournisseur:
ProSci Inc.
Description:
DC-SIGN peptide is used for blocking the activity of DC-SIGN antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4279P)
Fournisseur:
ProSci Inc.
Description:
ADAP peptide is used for blocking the activity of ADAP antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5795P)
Fournisseur:
ProSci Inc.
Description:
ATG3 peptide is used for blocking the activity of ATG3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5805P)
Fournisseur:
ProSci Inc.
Description:
IFITM1 peptide is used for blocking the activity of IFTIM1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5799P)
Fournisseur:
ProSci Inc.
Description:
ATG13 peptide is used for blocking the activity of ATG13 antibody.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI91-278)
Fournisseur:
ProSci Inc.
Description:
Human PAP, also known as 28 kDa heat- and acid-stable phosphoprotein, PDGF-associated protein, PDGFA-associated protein 1, PDAP1, HASPP28, is a protein which belongs to the PDAP1 family. The encoded protein in rodents has been shown to bind PDGFA with a low affinity. PDGF-Associated Protein (PAP) is a phosphoprotein that may enhance PDGFA-stimulated cell growth in fibroblasts, but inhibits the mitogenic effect of PDGFB. PDAP1 expression is induced by TNF-alpha, and cells overexpressing PDAP1 show significantly less apoptosis on exposure to TNF-alpha.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-290)
Fournisseur:
ProSci Inc.
Description:
Killer cell immunoglobulin-like receptor 2DL4(KIR2DL4) is a Single-pass type I membrane protein and contains 2 Ig-like C2-type (immunoglobulin-like) domains.It belongs to the immunoglobulin superfamily. KIR2DL4 is expressed in all NK cells and some T cells. KIR2DL4 activates the cytotoxicity of NK cells, despite the presence of an immunoreceptor tyrosine-based inhibition motif (ITIM) in its cytoplasmic tail. The ITIM was not necessary for activation of lysis by KIR2DL4. The activation signal of KIR2DL4 was sensitive to inhibition by another ITIM-containing receptor. The activation-deficient mutant of KIR2DL4 inhibited the signal delivered by the activating receptor CD16.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-287)
Fournisseur:
ProSci Inc.
Description:
VCAM-1 is a single-pass type I membrane protein, contains 7 Ig-like C2-type domains. It is an endothelial ligand for very late antigen-4 (VLA-4) and alpha4ß7 integrin expressed on leukocytes, and thus mediates leukocyte-endothelial cell adhesion and signal transduction. VCAM-1 expression is induced on endothelial cells during inflammatory bowel disease, atherosclerosis, allograft rejection, infection, and asthmatic responses. During these responses, VCAM-1 forms a scaffold for leukocyte migration. VCAM-1 also activates signals within endothelial cells resulting in the opening of an "endothelial cell gate" through which leukocytes migrate. VCAM-1 has been identified as a potential anti-inflammatory therapeutic target, the hypothesis being that reduced expression of VCAM-1 will slow the development of atherosclerosis. In addition, VCAM-1-activated signals in endothelial cells are regulated by cytokines indicating that it is important to consider both endothelial cell adhesion molecule expression and function during inflammatory processes.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5565P)
Fournisseur:
ProSci Inc.
Description:
SYNGR2 peptide is used for blocking the activity of SYNGR2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI2351P)
Fournisseur:
ProSci Inc.
Description:
NAK peptide is used for blocking the activity of NAK/TBK1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4269P)
Fournisseur:
ProSci Inc.
Description:
Carabin peptide is used for blocking the activity of Carabin antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4275P)
Fournisseur:
ProSci Inc.
Description:
MORF4 peptide is used for blocking the activity of MORF4 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-467)
Fournisseur:
ProSci Inc.
Description:
Interleukin-18-binding protein (IL18BP) is also known as Tadekinig-alfa, IL18BPa, which functions as an IL18 inhibitor. IL18BP is a secreted protein which contains one Ig-like C2-type (immunoglobulin-like) domain. IL18BP does not have a transmembrane domain and hence is not anchored to the cell membrane. IL18BP is strongly expressed in heart, lung, placenta and spleen. Isoform A of IL18BP binds to IL-18 and inhibits its activity. IL18BP also functions as an inhibitor of the early TH1 cytokine response. IL18BP suppresses the production of IFN-gamma resulting in reduced T-helper type 1 immune responses.
UOM:
1 * 200 µG
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