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Protéines et Peptides
Numéro de catalogue:
(PRSI7267P)
Fournisseur:
ProSci Inc.
Description:
19 amino acid peptide near the carboxy terminus of human PTRF.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7279P)
Fournisseur:
ProSci Inc.
Description:
19 amino acids near the center of human MOSPD1.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7271P)
Fournisseur:
ProSci Inc.
Description:
16 amino acids near the center of human Nucleobindin-2.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7243P)
Fournisseur:
ProSci Inc.
Description:
14 amino acid peptide near the carboxy terminus of human TNFSF4.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7239P)
Fournisseur:
ProSci Inc.
Description:
16 amino acid peptide near the carboxy terminus of human CCL17.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-429)
Fournisseur:
ProSci Inc.
Description:
Programmed death ligand 1 (PD-L1, B7-H1 or CD274) is a member of the growing B7 family of immune proteins that provide signals for both stimulating and inhibiting T cell activation. CD274 has been identified as one of two ligands for programmed death 1 (PD-1), a member of the CD28 family of immunoreceptors. CD274 is widely expressed in several organs such as heart, skeletal muscle, placenta and lung, and in lower amounts in thymus, spleen, kidney and liver. CD274 expression is upregulated in a small fraction of activated T and B cells and a much larger fraction of activated monocytes. CD274 expression is also induced in dendritic cells and keratinocytes after IFN-gamma stimulation. CD274 expression is also upregulated in a variety of tumour cell lines. Interaction of CD274 with PD-1 results in inhibition of TCR mediated proliferation and cytokine production, suggesting an inhibitory role in regulating immune responses. The CD274 - PD-1 pathway is involved in the negative regulation of some immune responses and may play an important role in the regulation of peripheral tolerance.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI90-520)
Fournisseur:
ProSci Inc.
Description:
Interleukin-22 (IL-22), also known as IL-10 related T cell derived inducible factor (ILTIF) was initially identified as a gene induced by IL-9 in mouse T cells and mast cells. IL-22 has been shown to activate STAT1 and STAT3 in several hepatoma cell lines and upregulate the production of acute phase proteins. IL-22 is produced by normal T cells upon anti-CD3 stimulation in humans. Mouse IL-22 expression is also induced in various organs upon lipopolysaccharide injection, suggesting that IL-22 may be involved in inflammatory responses. The functional IL-22 receptor complex consists of two receptor subunits, IL-22R(CRF29) and IL-10Rbeta(CRF24), belonging to the class II cytokine receptor family.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI90-525)
Fournisseur:
ProSci Inc.
Description:
Interleukin-23 (IL-23) is a heterodimeric cytokine composed of two disulfide-linked subunits, a p19 subunit that is unique to IL-23, and a p40 subunit that is shared with IL-12 (1-5). Although p19 is expressed by activated macrophages, dendritic cells, T cells, and endothelial cells, only activated macrophages and dendritic cells express p40 concurrently to produce IL-23. The functional IL-23 receptor complex consists of two receptor subunits, the IL-12 receptor beta 1 subunit (IL-12 Rbeta1) and the IL-23-specific receptor subunit (IL-23 R). IL-23 has biological activities that are similar to, but distinct from IL-12. Both IL-12 and IL-23 induce proliferation and IFN-gamma production by human T cells. While IL-12 acts on both naie and memory human T cells, the effects of IL-23 is restricted to memory T cells. In mouse, IL-23 but not IL-12, has also been shown to induce memory T cells to secret IL-17, a potent proinflammatory cytokine. IL-12 and IL-23 can induce IL-12 production from mouse splenic DC of both the CD8-and CD8+ subtypes, however only IL-23 can act directly on CD8+ DC to mediate immunogenic presentation of poorly immunogenic tumour/self peptide.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6959P)
Fournisseur:
ProSci Inc.
Description:
CLEC2A peptide is used for blocking the activity of CLEC2A antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6961P)
Fournisseur:
ProSci Inc.
Description:
CRIM1 peptide is used for blocking the activity of CRIM1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6955P)
Fournisseur:
ProSci Inc.
Description:
TCTEX1D3 peptide is used for blocking the activity of TCTEX1D3 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6951P)
Fournisseur:
ProSci Inc.
Description:
TCTEX1D1 peptide is used for blocking the activity of TCTEX1D1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-110)
Fournisseur:
ProSci Inc.
Description:
Hematopoietic Prostaglandin D Synthase (HPGDS) belongs to the GST superfamily and Sigma family. HPGDS contains one GST C-terminal domain and one GST N-terminal domain. HPGDS is highly expressed in adipose tissue, macrophages, and placenta, and it exists in the form of homodimer in living body. HPGDS is a cytosolic enzyme that isomerizes PGH(2). HPGDS is a bifunctional enzyme that catalyzes both the conversion of PGH2 to PGD2 and also shows low glutathione-peroxidase activity towards cumenehydroperoxide.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-647)
Fournisseur:
ProSci Inc.
Description:
CD64, also known as Fc-gamma receptor 1 (Fc gamma RI), is a type of integral membrane glycoprotein that binds monomeric IgG-type antibodies with high affinity. After binding IgG, CD64 interacts with an accessory chain known as the common gamma chain ( gamma chain), which possesses an ITAM motif that is necessary for triggering cellular activation. CD64 is composed of a signal peptide, three extracellular immunoglobulin domains of the C2-type used to bind antibody, a hydrophobic transmembrane domain, and a short cytoplasmic tail. CD64 mediates endocytosis, phagocytosis, antibody-dependent cellular cytotoxicity, cytokine release, and superoxide production. It is normally expressed on the surfaces of monocytes and macrophages.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-654)
Fournisseur:
ProSci Inc.
Description:
CD47 is involved in the increase in intracellular calcium concentration that occurs upon cell adhesion to extracellular matrix. The protein is also a receptor for the C-terminal cell-binding domain of thrombospondin, and it may play a role in membrane transport and signal transduction. This protein has broad tissue distribution, and is reduced in expression on Rh erythrocytes.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6165P)
Fournisseur:
ProSci Inc.
Description:
FBXL16 peptide is used for blocking the activity of FBXL16 antibody.
UOM:
1 * 50 µG
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