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Protéines et Peptides
Numéro de catalogue:
(PRSI91-330)
Fournisseur:
ProSci Inc.
Description:
Junctional Adhesion Molecule B (JAM-B) is a single-pass type I membrane protein that belongs to the juctional adhesion molecules family. JAM-B includes a signal sequence (aa 1-28), an extracellular region (aa 29-238) with one Ig-like C2-type domain and one Ig-like V-type domain, a transmembrane segment (aa 239-259), and a cytoplasmic domain (aa 260 - 298). JAMB is localized to the tight junctions between endothelial cells or epithelial cells. JAM-B is prominently expressed in the heart, placenta, lung, foreskin and lymph node. It is also present on the endothelia of other vessels. JAM-B acts as an adhesive ligand for interacting with a variety of immune cell types and may play a role in lymphocyte homing to secondary lymphoid organs.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3415P)
Fournisseur:
ProSci Inc.
Description:
Anthrax peptide is used for blocking the activity of Anthrax lethal factor antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3411P)
Fournisseur:
ProSci Inc.
Description:
Anthrax peptide is used for blocking the activity of Anthrax PA antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3409P)
Fournisseur:
ProSci Inc.
Description:
XAF-1 peptide is used for blocking the activity of XAF-1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-042)
Fournisseur:
ProSci Inc.
Description:
β2 microglobulin is also known as Beta-2-microglobulin (B2M), is a component of MHC class I molecules which belongs to the beta-2-microglobulin family. B2M is present on all nucleated cells (excludes red blood cells). B2M associates not only with the alpha chain of MHC class I molecules, but also with class I-like molecules such as CD1 and Qa. An additional function of B2M is association with the HFE protein, together regulating the expression of hepcidin in the liver which targets the iron transporter ferroportin on the cytoplasmic membrane of enterocytes and macrophages for degradation resulting in decreased iron uptake from food and iron release from recycled red blood cells respectively. Loss of this function causes iron excess and hemochromatosis. Defects in B2M are the cause of hypercatabolic hypoproteinemia (HYCATHYP).
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4617P)
Fournisseur:
ProSci Inc.
Description:
Syntaphilin peptide is used for blocking the activity of Syntaphilin antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4635P)
Fournisseur:
ProSci Inc.
Description:
Syntaphilin peptide is used for blocking the activity of Syntaphilin antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4387P)
Fournisseur:
ProSci Inc.
Description:
Grik2 peptide is used for blocking the activity of Grik2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4381P)
Fournisseur:
ProSci Inc.
Description:
Grik1 peptide is used for blocking the activity of Grik1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4393P)
Fournisseur:
ProSci Inc.
Description:
Grik4 peptide is used for blocking the activity of Grik4 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI96-179)
Fournisseur:
ProSci Inc.
Description:
Carcinoembryonic antigen-related cell adhesion molecule 6 (non-specific cross reacting antigen) (CEACAM6) is also known as CD66c (Cluster of Differentiation 66c), CEAL, NCA, and is one of seven human CEACAM family members within the immunoglobulin superfamily. In humans, CEACAMs include type I transmembrane proteins (CEACAM1, CEACAM3, and CEACAM4) and GPI-linked molecules (CEACAM5 through CEACAM8). There is no human CEACAM2. CEACAM 6 contains one N-terminal V-type Ig-like domain (N domain), followed by two C2-type Ig-like domains. It shows considerable glycosylation, including (sialyl) LewisX, which mediates binding to E-selectin, galectins and some bacterial fimbrae. CEACAM-6 is expressed by granulocytes and their progenitors. It is also expressed by epithelia of various organs and is upregulated in pancreatic and colon adenocarcinomas, as well as hyperplastic polyps. Resistance to adhesion-related apoptosis in tumor cells is conferred in the condition of CEACAM6 overexpression.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI3475P)
Fournisseur:
ProSci Inc.
Description:
Caspase-8 peptide is used for blocking the activity of Caspase-8 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3501P)
Fournisseur:
ProSci Inc.
Description:
Rheb peptide is used for blocking the activity of the Rheb antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3509P)
Fournisseur:
ProSci Inc.
Description:
TSC2 peptide is used for blocking the activity of the TSC2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-104)
Fournisseur:
ProSci Inc.
Description:
Stromal Cell-Derived Factor-1 (SDF-1) is a chemokine member of the intercrine family. SDF1 is expressed as five isoforms that differ only in the C terminal tail. SDF1 alpha and SDF1 beta are identical except for the four residues present in the C-terminus of SDF1 beta but absent from SDF1 alpha. SDF1 isoforms interact with CXCR4 and CXCR7 receptors on the cell surface, and can also bind syndecan4. SDF1 is known to influence lymphopoiesis, regulate patterning and cell number of neural progenitors, and promote angiogenesis. It also enhances the survival of myeloid progenitor cells.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-167)
Fournisseur:
ProSci Inc.
Description:
Ubiquitin-Conjugating Enzyme E2 T (UBE2T) is a ligase that belongs to the Ubiquitin-Conjugating Enzyme family. UBE2T accepts the ATP-dependent ubiquitin from the E1 complex and catalyzes its covalent attachment to other proteins. In vitro, UBE2T is able to catalyze polyubiquitination using all 7 ubiquitin Lys residues, but may prefer 'Lys-11'-, 'Lys-27'-, 'Lys-48'- and 'Lys-63'-linked polyubiquitination. UBE2T is an important factor of the Faconi anemia pathway of DNA damage repair and, upon self-inactivation, may negatively regulate the Faconi pathway.
UOM:
1 * 50 µG
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