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Anticorps
Numéro de catalogue:
(BOSSBS-2419R-CY5)
Fournisseur:
Bioss
Description:
The KIR family consists of transmembrane glycoproteins of the Ig superfamily expressed on natural killer (NK) cells and a subset of human T cells. KIR2DL1 is a receptor on human NK cells for HLA-C alleles. It inhibits the activity of NK cells thus preventing cell lysis.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11999R-CY3)
Fournisseur:
Bioss
Description:
Targets the cAMP-dependent protein kinase (PKA) to the plasma membrane, and permits functional coupling to the L-type calcium channel. The membrane-associated form reduces epithelial sodium channel (ENaC) activity, whereas the free cytoplasmic form may negatively regulate ENaC channel feedback inhibition by intracellular sodium.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-9203R-CY5)
Fournisseur:
Bioss
Description:
CD300C , also known as CLM-6 (CMRF35-like molecule 6), is a 224 amino acid single-pass type I membrane protein that is present on the surface of neutrophils, monocytes and a select proportion of peripheral blood B and T lymphocytes. CD300C contains two potential N-gylcosylation sites, a potential O-glycosylated hinge-like region and an Ig-like V-type (immunoglobulin-like) domain that is very similar to the Fc receptor for polymeric IgA and IgM. The gene encoding CD300C is localized to a region on human chromosome 17 that harbors a susceptilibty locus for psoriasis, dermatitis and rheumatoid arthritis, suggesting a possible involvement of CD300C with these conditions.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5295R-HRP)
Fournisseur:
Bioss
Description:
DNA (cytosine-5-)-methyltransferase 1 has a role in the establishment and regulation of tissue-specific patterns of methylated cytosine residues. Aberrant methylation patterns are associated with certain human tumors and developmental abnormalities. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008].
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1863R-FITC)
Fournisseur:
Bioss
Description:
DNAJC3 may act as an inhibitor of both the autophosphorylation of EIF2AK2/PKR and the ability of EIF2AK2/PKR to catalyze phosphorylation of the EIF2A. It also functions as a Co-chaperone of HSPA8/HSC70 and is involved in the unfolded protein response (UPR) during ER stress. It has been reported that this protein stimulates the ATPase activity of HSPA8/HSC70.DNAJC3 is also involved in ativiral defense - it is activated in response to infection by influenza virus through the dissociation of DNAJB1. DNAJC3 is widely expressed and can be found at high levels in the testis and pancreas (expression in cell lines is variable).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0166R-CY5)
Fournisseur:
Bioss
Description:
This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K >substance K >substance P.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0166R-CY7)
Fournisseur:
Bioss
Description:
This is a receptor for the tachykinin neuropeptide neuromedin-K (neurokinin B). It is associated with G proteins that activate a phosphatidylinositol-calcium second messenger system. The rank order of affinity of this receptor to tachykinins is: neuromedin-K >substance K >substance P.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-18635R-A680)
Fournisseur:
Bioss
Description:
Essential for the regulation of ciliary length and required for the long-term survival of photoreceptors (By similarity). Phosphorylates FZR1 in a cell cycle-dependent manner. Plays a role in the transcriptional coactivation of AR. Could play an important function in spermatogenesis. May play a role in chromosomal stability in prostate cancer cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0862R-A555)
Fournisseur:
Bioss
Description:
Insulin decreases blood glucose concentration. It increases cell permeability to monosaccharides, amino acids and fatty acids. It accelerates glycolysis, the pentose phosphate cycle, and glycogen synthesis in liver.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2516R-CY7)
Fournisseur:
Bioss
Description:
May be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis. Overexpression delays G2/M phase progression.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6199R-A488)
Fournisseur:
Bioss
Description:
Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13336R-A750)
Fournisseur:
Bioss
Description:
Glial fibrillary acidic protein (GFAP) is a member of the class III intermediate filament protein family. It is heavily, and specifically, expressed in astrocytes and certain other astroglia in the central nervous system, in satellite cells in peripheral ganglia, and in non myelinating Schwann cells in peripheral nerves. In addition, neural stem cells frequently strongly express GFAP. to GFAP are therefore very useful as markers of astrocytic cells. In addition many types of brain tumor, presumably derived from astrocytic cells, heavily express GFAP. GFAP is also found in the lens epithelium, Kupffer cells of the liver, in some cells in salivary tumors and has been reported in erythrocytes.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6199R-A350)
Fournisseur:
Bioss
Description:
Signaling adapter that couples activated growth factor receptors to signaling pathway in neurons. Involved in the signal transduction pathways of neurotrophin-activated Trk receptors in cortical neurons.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6034R-A555)
Fournisseur:
Bioss
Description:
Three different forms of human pancreatic procarboxypeptidase A have been isolated. This gene encodes a monomeric pancreatic exopeptidase involved in zymogen inhibition. [provided by RefSeq, Jan 2009].
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2518R-A488)
Fournisseur:
Bioss
Description:
Plays a critical role in MHC class II antigen processing by stabilizing peptide-free class II alpha/beta heterodimers in a complex soon after their synthesis and directing transport of the complex from the endoplasmic reticulum to the endosomal/lysosomal system where the antigen processing and binding of antigenic peptides to MHC class II takes place. Serves as cell surface receptor for the cytokine MIF.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2516R-CY5.5)
Fournisseur:
Bioss
Description:
May be involved in p53-induced cell cycle arrest in G2/M phase by interfering with microtubule rearrangements that are required to enter mitosis. Overexpression delays G2/M phase progression.
UOM:
1 * 100 µl
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