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Anticorps
Numéro de catalogue:
(BOSSBS-7930R-CY5.5)
Fournisseur:
Bioss
Description:
Tissue specificity:Widely expressed. Most abundant in testis, skeletal muscle, and heart.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3711R-FITC)
Fournisseur:
Bioss
Description:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277). [provided by RefSeq, Feb 2013].
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-11459R-A488)
Fournisseur:
Bioss
Description:
FARP2 is a 1,545 amino acid protein that contains one FERM domain, one DH domain and two PH domains. It exists as two alternatively spliced isoforms that are abundantly expressed in brain, lung, and testis as well as in embryonic hippocampal and cortical neurons. FARP2 functions as a Rho-guanine nucleotide exchange factor that activates RAC1 and is thought to regulate neurite remodeling of embryonic neurons. Sema3A binding to neuropilin-1 induces the dissociation of FARP2 from plexin-A1, thereby activating FARP2's Rac GEF activity which is critical for repulsion of outgrowing axons and suppression of neuronal adhesion. Downregulation of the FARP2 gene has been implicated in autism.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3712R-CY7)
Fournisseur:
Bioss
Description:
G-protein coupled receptor that functions as receptor for endogenous enkephalins and for a subset of other opioids. Ligand binding causes a conformation change that triggers signaling via guanine nucleotide-binding proteins (G proteins) and modulates the activity of down-stream effectors, such as adenylate cyclase. Signaling leads to the inhibition of adenylate cyclase activity. Inhibits neurotransmitter release by reducing calcium ion currents and increasing potassium ion conductance. Plays a role in the perception of pain and in opiate-mediated analgesia. Plays a role in developing analgesic tolerance to morphine.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7930R-HRP)
Fournisseur:
Bioss
Description:
Tissue specificity:Widely expressed. Most abundant in testis, skeletal muscle, and heart.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-3711R-A750)
Fournisseur:
Bioss
Description:
This gene encodes a tumor suppressor protein containing transcriptional activation, DNA binding, and oligomerization domains. The encoded protein responds to diverse cellular stresses to regulate expression of target genes, thereby inducing cell cycle arrest, apoptosis, senescence, DNA repair, or changes in metabolism. Mutations in this gene are associated with a variety of human cancers, including hereditary cancers such as Li-Fraumeni syndrome. Alternative splicing of this gene and the use of alternate promoters result in multiple transcript variants and isoforms. Additional isoforms have also been shown to result from the use of alternate translation initiation codons (PMIDs: 12032546, 20937277).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13490R-A555)
Fournisseur:
Bioss
Description:
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is a type II Golgi-resident protein. It may process proteins synthesized in the rough endoplasmic reticulum and assist in the transport of protein cargo through the Golgi apparatus. [provided by RefSeq, Jul 2008].
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2332R-CY7)
Fournisseur:
Bioss
Description:
Catalyzes the terminal and only committed step in triacylglycerol synthesis by using diacylglycerol and fatty acyl CoA as substrates. In contrast to DGAT2 it is not essential for survival. May be involved in VLDL (very low density lipoprotein) assembly. In liver, plays a role in esterifying exogenous fatty acids to glycerol. Functions as the major acyl-CoA retinol acyltransferase (ARAT) in the skin, where it acts to maintain retinoid homeostasis and prevent retinoid toxicity leading to skin and hair disorders.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6103R-A350)
Fournisseur:
Bioss
Description:
May contribute to specialized endoplasmic reticulum functions in neurons.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0633R-CY5)
Fournisseur:
Bioss
Description:
Ser/Thr-kinase component of cyclin D-CDK4 (DC) complexes that phosphorylate and inhibit members of the retinoblastoma (RB) protein family including RB1 and regulate the cell-cycle during G(1)/S transition. Phosphorylation of RB1 allows dissociation of the transcription factor E2F from the RB/E2F complexes and the subsequent transcription of E2F target genes which are responsible for the progression through the G(1) phase. Hypophosphorylates RB1 in early G(1) phase. Cyclin D-CDK4 complexes are major integrators of various mitogenenic and antimitogenic signals. Also phosphorylates SMAD3 in a cell-cycle-dependent manner and represses its transcriptional activity. Component of the ternary complex, cyclin D/CDK4/CDKN1B, required for nuclear translocation and activity of the cyclin D-CDK4 complex.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13489R-A680)
Fournisseur:
Bioss
Description:
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is localized at the Golgi stack and may have a regulatory role in Golgi trafficking.
UOM:
1 * 100 µl
Numéro de catalogue:
(USBI043514-HRP)
Fournisseur:
US Biological
Description:
Anti-UBE2D2 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
UOM:
1 * 200 µl
Numéro de catalogue:
(USBI043512-PE)
Fournisseur:
US Biological
Description:
Anti-UBE2C Rabbit Polyclonal Antibody (PE (Phycoerythrin))
UOM:
1 * 200 µl
Numéro de catalogue:
(USBI037733-FITC)
Fournisseur:
US Biological
Description:
Anti-LEMD2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
UOM:
1 * 200 µl
Numéro de catalogue:
(USBI043508-FITC)
Fournisseur:
US Biological
Description:
Anti-UBAP2L Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
UOM:
1 * 200 µl
Numéro de catalogue:
(USBI043512-AP)
Fournisseur:
US Biological
Description:
Anti-UBE2C Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
UOM:
1 * 200 µl
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