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Bioss
Numéro de catalogue:
(BOSSBS-8670R-CY3)
Fournisseur:
Bioss
Description:
The genus Salmonella is a member of the family Enterobacteriaceae. The genus is composed of Gram-negative bacilli that are facultative and flagellated (motile). Salmonellae possess 3 major antigens; the "H" or flagellar antigen (phase 1 & 2), the "O" or somatic antigen (part of the LPS moiety) and the "Vi" or capsular antigen (referred to as "K" in other Enterobacteriaceae). Salmonellae also possess the LPS endotoxin characteristic of Gram-negative bacteria. This LPS is composed of an "O" polysaccharide ("O" antigen) an "R" core and the endotoxic inner "Lipid A". Endotoxins evoke fever and can activate complement, kinin and clotting factors. The commonest Salmonella serotype associated with food borne infections in humans is Salmonella enteriditis and in particular phage type 4 (PT4). Salmonella Enteriditis bacteria may be found in the intestinal tracts of livestock, poultry, dogs, cats and other warm-blooded animals. This strain is only one of about 2,000 kinds of Salmonella bacteria; it is often associated with poultry and eggs.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8671R-A680)
Fournisseur:
Bioss
Description:
Key component of the cytosolic iron-sulfur protein assembly (CIA) complex, a multiprotein complex that mediates the incorporation of iron-sulfur cluster into apoproteins specifically involved in DNA metabolism and genomic integrity. In the CIA complex, MMS19 acts as an adapter between early-acting CIA components and a subset of cellular target iron-sulfur proteins such as ERCC2/XPD, FANCJ and RTEL1, thereby playing a key role in nucleotide excision repair (NER) and RNA polymerase II (POL II) transcription. As part of the mitotic spindle-associated MMXD complex, plays a role in chromosome segregation, probably by facilitating iron-sulfur cluster assembly into ERCC2/XPD. Indirectly acts as a transcriptional coactivator of estrogen receptor (ER), via its role in iron-sulfur insertion into some component of the TFIIH-machinery.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13239R-CY7)
Fournisseur:
Bioss
Description:
Receptor for Wnt proteins. Most of frizzled receptors are coupled to the beta-catenin canonical signaling pathway, which leads to the activation of disheveled proteins, inhibition of GSK-3 kinase, nuclear accumulation of beta-catenin and activation of Wnt target genes. A second signaling pathway involving PKC and calcium fluxes has been seen for some family members, but it is not yet clear if it represents a distinct pathway or if it can be integrated in the canonical pathway, as PKC seems to be required for Wnt-mediated inactivation of GSK-3 kinase. Both pathways seem to involve interactions with G-proteins. May be involved in transduction and intercellular transmission of polarity information during tissue morphogenesis and/or in differentiated tissues.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5838R-A555)
Fournisseur:
Bioss
Description:
Can mediate aggregation most likely through a homophilic molecular interaction.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5838R-CY5)
Fournisseur:
Bioss
Description:
Can mediate aggregation most likely through a homophilic molecular interaction.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5838R-CY3)
Fournisseur:
Bioss
Description:
Can mediate aggregation most likely through a homophilic molecular interaction.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5838R-A350)
Fournisseur:
Bioss
Description:
Can mediate aggregation most likely through a homophilic molecular interaction.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13489R-A647)
Fournisseur:
Bioss
Description:
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is localized at the Golgi stack and may have a regulatory role in Golgi trafficking.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6214R-A680)
Fournisseur:
Bioss
Description:
The protein encoded by this gene is an NADPH-dependent retinal reductase and a short-chain dehydrogenase/reductase. The encoded protein has no steroid dehydrogenase activity.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6214R-FITC)
Fournisseur:
Bioss
Description:
The protein encoded by this gene is an NADPH-dependent retinal reductase and a short-chain dehydrogenase/reductase. The encoded protein has no steroid dehydrogenase activity.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13489R-A488)
Fournisseur:
Bioss
Description:
The Golgi complex plays a key role in the sorting and modification of proteins exported from the endoplasmic reticulum. The protein encoded by this gene is localized at the Golgi stack and may have a regulatory role in Golgi trafficking.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2216R-A750)
Fournisseur:
Bioss
Description:
Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2216R-CY5)
Fournisseur:
Bioss
Description:
Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0547R-FITC)
Fournisseur:
Bioss
Description:
COLA18A probably plays a major role in determining the retinal structure as well as in the closure of the neural tube. Endostatin potently inhibits endothelial cell proliferation and angiogenesis. May inhibit angiogenesis by binding to the heparan sulfate proteoglycans involved in growth factor signaling.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-8579R-CY3)
Fournisseur:
Bioss
Description:
The finding that mutations in DNA mismatch repair genes are associated with hereditary nonpolyposis colorectal cancer (HNPCC) has resulted in considerable interest in the understanding of the mechanism of DNA mismatch repair. Initially, inherited mutations in the MSH2 and MLH1 homologs of the bacterial DNA mismatch repair genes MutS and MutL were demonstrated at high frequency in HNPCC and were shown to be associated with microsatellite instability. The demonstration that 10 to 45% of pancreatic, gastric, breast, ovarian and small cell lung cancers also display microsatellite instability has been interpreted to suggest that DNA mismatch repair is not restricted to HNPCC tumors but is a common feature in tumor initiation or progression. Two additional homologs of the prokaryotic MutL gene, designated PMS1 and PMS2, have been identified and shown to be mutated in the germline of HNPCC patients.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-4937R-CY5.5)
Fournisseur:
Bioss
Description:
Cystatin A and cystatin B (also designated PME, CST6, STFB, CPI-B, stefin B and liver thiol proteinase inhibitor) are thiol protease inhibitors that form complexes with papain and the cathepsins B, H, and L. Cystatin A, a cytoplasmic protein, is one of the precursor proteins of the cornified cell envelope in keratinocytes and plays a role in epidermal development and maintenance. Cystatin B protects against intracellular proteases leaking out of lysosomes and is primarily expressed in heart, liver and kidney.
UOM:
1 * 100 µl
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