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Bioss
Numéro de catalogue:
(BOSSBS-12151R-HRP)
Fournisseur:
Bioss
Description:
May regulate IL2 production by T-cells. May be involved in neuron regeneration.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5487R-CY5.5)
Fournisseur:
Bioss
Description:
phosphorylated at the Thr-Pro-Tyr phosphorylation motif instead of the characteristic MAP kinase Thr-Glu-Tyr motif. JNK2 (p54a, SAPK1a), along with JNK1 and JNK3, is thought to play an important role in nuclear signal transduction through its environmental stress activation and subsequent phosphorylation of the nuclear transcription factor p53.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13366R-CY3)
Fournisseur:
Bioss
Description:
GK2 is a 553 amino acid protein that belongs to the FGGY kinase family and is involved in the pathway of glycerol degradation. Localized to the outer membrane of the mitochondrion and expressed at high levels in testis, GK2 functions to catalyze the ATP-dependent conversion of glycerol to glycerol 3-phosphate. Via its catalytic activity, GK2 plays an essential role in the regulation of glycerol uptake and metabolism. The gene encoding GK2 maps to chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2419R-CY7)
Fournisseur:
Bioss
Description:
The KIR family consists of transmembrane glycoproteins of the Ig superfamily expressed on natural killer (NK) cells and a subset of human T cells. KIR2DL1 is a receptor on human NK cells for HLA-C alleles. It inhibits the activity of NK cells thus preventing cell lysis.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-2420R-CY3)
Fournisseur:
Bioss
Description:
Cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13366R-A680)
Fournisseur:
Bioss
Description:
GK2 is a 553 amino acid protein that belongs to the FGGY kinase family and is involved in the pathway of glycerol degradation. Localized to the outer membrane of the mitochondrion and expressed at high levels in testis, GK2 functions to catalyze the ATP-dependent conversion of glycerol to glycerol 3-phosphate. Via its catalytic activity, GK2 plays an essential role in the regulation of glycerol uptake and metabolism. The gene encoding GK2 maps to chromosome 4, which encodes nearly 6% of the human genome and has the largest gene deserts (regions of the genome with no protein encoding genes) of all of the human chromosomes. Defects in some of the genes located on chromosome 4 are associated with Huntington's disease, Ellis-van Creveld syndrome, methylmalonic acidemia and polycystic kidney disease.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-6006R-A750)
Fournisseur:
Bioss
Description:
FBXO31 belongs to the F-box protein family. Such proteins are characterised by an F-box motif of approximately 40 residues. F-box proteins interact with SKP1 through the F box and they interact with ubiquitination targets through other protein interaction domains. There are two different isoforms.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0196R-A750)
Fournisseur:
Bioss
Description:
Growth factor that plays an essential role in the regulation of embryonic development, cell proliferation, cell migration, survival and chemotaxis. Potent mitogen for cells of mesenchymal origin. Required for normal lung alveolar septum formation during embryogenesis, normal development of the gastrointestinal tract, normal development of Leydig cells and spermatogenesis. Required for normal oligodendrocyte development and normal myelination in the spinal cord and cerebellum. Plays an important role in wound healing. Signaling is modulated by the formation of heterodimers with PDGFB (By similarity).
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0199R-A555)
Fournisseur:
Bioss
Description:
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12947R-A555)
Fournisseur:
Bioss
Description:
CRP2BP is a 782 amino acid protein encoded by the human gene CSRP2BP. CRP2BP specifically interacts with the double LIM domain protein CRP2. The LIM domain is a conserved cysteine and histidine-containing structural module of two tandemly arranged zinc fingers. It has been identified in single or multiple copies in a variety of regulatory proteins, either in combination with defined functional domains, like homeodomains, or alone, like in the CRP family of LIM proteins. Members of the cysteine- and glycine-rich protein family (CRP1, CRP2 and CRP3) contain two zinc-binding LIM domains, LIM1 (amino-terminal) and LIM2 (carboxyl-terminal), and are implicated in diverse cellular processes linked to differentiation, growth control and pathogenesis. Although present in cytoplasm, CRP2BP is mainly a ubiquitously expressed nuclear protein, with highest expression in skeletal muscle and heart.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0199R-CY5)
Fournisseur:
Bioss
Description:
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-12946R-CY7)
Fournisseur:
Bioss
Description:
CRP2 is a 193 amino acid nuclear protein that belongs to the CRP family of LIM domain proteins. Highly expressed in smooth muscle of aorta, CRP2 is thought to have a role in embryonic vascular system development and is downregulated following cell injury or PDGF-B exposure. CRP2 contains two LIM zinc-binding domains and is encoded by a gene that maps to human chromosome 12, which encodes over 1,100 genes and comprises approximately 4.5% of the human genome. Chromosome 12 is associated with a variety of diseases and afflictions, including hypochondrogenesis, achondrogenesis, Kniest dysplasia, Noonan syndrome and trisomy 12p, which causes facial developmental defects and seizure disorders.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0199R-A647)
Fournisseur:
Bioss
Description:
GFAP, a class-III intermediate filament, is a cell-specific marker that, during the development of the central nervous system, distinguishes astrocytes from other glial cells.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1834R-HRP)
Fournisseur:
Bioss
Description:
IL20 is a cytokine structurally related to interleukin 10 (IL10). This cytokine has been shown to transduce its signal through signal transducer and activator of transcription 3 (STAT3) in keratinocytes. A specific receptor for this cytokine is expressed in skin and upregulated dramatically in psoriatic skin, suggesting a role for this protein in epidermal function and psoriasis.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-13276R-A350)
Fournisseur:
Bioss
Description:
Crystallins are the major proteins of the vertebrate eye lens, where they maintain the transparency and refractive index of the lens. Crystallins are divided into alpha, beta, and gamma families, and the beta and gamma-crystallins also comprise a superfamily. Crystallins usually contain seven distinctive protein regions, including four homologous motifs, a connecting peptide, and N- and C-terminal extensions. gamma-crystallins are structural proteins in the lens, and they exists as monomers which typically lack connecting peptides and terminal extensions. The gamma-crystallins include seven closely related gamma A, gamma B, gamma C, gamma D, gamma E, gamma F, and gamma G-crystallin, as well as the gamma N and gamma S-crystallin genes. The gamma-crystallins are differentially regulated after early development, and are involved in cataract formation as a result of either age-related protein degradation or genetic mutation.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-5685R-A750)
Fournisseur:
Bioss
Description:
Transcription factor involved in osteoblastic differentiation and skeletal morphogenesis. Essential for the maturation of osteoblasts and both intramembranous and endochondral ossification. CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukaemia virus, polyomavirus enhancer, T-cell receptor enhancers, osteocalcin, osteopontin, bone sialoprotein, alpha 1(I) collagen, LCK, IL-3 and GM-CSF promoters. In osteoblasts, supports transcription activation: synergizes with SPEN/MINT to enhance FGFR2-mediated activation of the osteocalcin FGF-responsive element (OCFRE) (By similarity). Inhibits KAT6B-dependent transcriptional activation.
UOM:
1 * 100 µl
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est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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