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ProSci Inc.
Numéro de catalogue:
(PRSI14-234)
Fournisseur:
ProSci Inc.
Description:
Anti-RPL38 Rabbit Polyclonal Antibody
UOM:
1 * 50 µl
New Product
Numéro de catalogue:
(PRSI57-365)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI24-372)
Fournisseur:
ProSci Inc.
Description:
Anti-GPR119 Recombinant Antibody [Clone: Gipg013]
UOM:
1 * 0,2 mg
New Product
Numéro de catalogue:
(PRSI24-365)
Fournisseur:
ProSci Inc.
Description:
Anti-TUBA1A Recombinant Antibody [Clone: F2C]
UOM:
1 * 0,2 mg
New Product
Numéro de catalogue:
(PRSI34-028)
Fournisseur:
ProSci Inc.
Description:
Prostate specific acid phosphatase (PSAP) is an enzyme that catalyses the conversion of orthophosphoric monoester to alcohol and orthophosphate. It is synthesised under androgen regulation and is secreted by the epithelial cells of the prostate gland. PSAP is found in non-neoplastic adult and fetal prostatic glands, primary and metastatic prostatic carcinomas. It shows no staining in granulocytes, osteoclasts, parietal cells of the stomach, liver cells, renal cell or breast carcinomas.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI34-053)
Fournisseur:
ProSci Inc.
Description:
Mastermind-like 3 is a nuclear speckle protein that acts as a transcriptional coactivator for Notch receptors. The Notch signaling pathway influences cell fate by regulating the ability of precursor cells to properly respond to developmental signals. MAml3 is a member of the mastermind-like family of proteins that are human homologs of the Drosophila melanogaster mastermind protein. Through its N-terminal region, MAml3 interacts with the ankyrin repeats of the Notch 1-4 proteins. This interaction leads to formation of a DNA-binding complex with the Notch proteins and RBP-Jκ; a complex that can then induce HES1 gene expression. While the N-terminal domain of MAml3 is essential for proper Notch binding, the C-terminal domain is essential for transcriptional activation. Due to its involvement in cell signaling and transcriptional activation, its upregulation is thought to be involved in oncogenesis.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI34-024)
Fournisseur:
ProSci Inc.
Description:
Together, Ku70 and Ku80 make up the Ku heterodimer, which binds to DNA double-strand break ends and is required for the non-homologous end joining (NHEJ) pathway of DNA repair. It is also required for V(D)J recombination, which utilizes the NHEJ pathway to promote antigen diversity in the mammalian immune system. In addition to its role in NHEJ, Ku is also required for telomere length maintenance and subtelomeric gene silencing. Ku was originally identified when patients with systemic lupus erythematosus were found to have high levels of autoantibodies to the protein. [Wiki].
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI34-023)
Fournisseur:
ProSci Inc.
Description:
Expression of NKX2.2 has been found in neuroendocrine tumors of the gut, making it a potential marker for the study of gastrointestinal neuroendocrine tumors. More recently, NKX2.2 protein was identified as a target of EWS-FLI-1, the fusion protein specific to Ewing sarcoma, and was shown to be differentially upregulated in Ewing sarcoma on the basis of array-based gene expression analysis. antibody to NKX2.2 detects a valuable marker for Ewing sarcoma, with a sensitivity of 93% and a specificity of 89%, and aids in the differential diagnosis of small round cell tumors.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI34-010)
Fournisseur:
ProSci Inc.
Description:
The Cell-division cycle protein 20 is an essential regulator of cell division that is encoded by the CDC20 gene in humans. To the best of current knowledge its most important function is to activate the anaphase promoting complex (APC/C), a large 11-13 subunit complex that initiates chromatid separation and entrance into anaphase. The APC/C-Cdc20 protein complex has two main downstream targets. Firstly, it targets securin for destruction, enabling the eventual destruction of cohesin and thus sister chromatid separation. It also targets S and M-phase (S/M) cyclins for destruction, which inactivates S/M cyclin-dependent kinases (Cdks) and allows the cell to exit from mitosis. A closely related protein, Cdc20homologue-1 (Cdh1) plays a complementary role in the cell cycle.<p>Cdc20 appears to act as a regulatory protein interacting with many other proteins at multiple points in the cell cycle. It is required for two microtubule-dependent processes: nuclear movement prior to anaphase, and chromosome separation. [Wiki].
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI34-048)
Fournisseur:
ProSci Inc.
Description:
EpCAM may act as a physical homophilic interaction molecule between intestinal epithelial cells (IECs) and intraepithelial lymphocytes (IELs) at the mucosal epithelium for providing immunological barrier as a first line of defense against mucosal infection. [UniProt].
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI56-978)
Fournisseur:
ProSci Inc.
Description:
This gene encodes a chromatin-associated enzyme, poly(ADP-ribosyl)transferase, which modifies various nuclear proteins by poly(ADP-ribosyl)ation. The modification is dependent on DNA and is involved in the regulation of various important cellular processes such as differentiation, proliferation, and tumor transformation and also in the regulation of the molecular events involved in the recovery of cell from DNA damage. In addition, this enzyme may be the site of mutation in Fanconi anemia, and may participate in the pathophysiology of type I diabetes.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI61-924)
Fournisseur:
ProSci Inc.
Description:
For WB starting dilution is: 1:1000. For IHC-P starting dilution is: 1:10~50.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI22-433)
Fournisseur:
ProSci Inc.
Description:
Anti-RBP2 Rabbit Polyclonal Antibody
UOM:
1 * 50 µl
New Product
Numéro de catalogue:
(PRSI22-483)
Fournisseur:
ProSci Inc.
Description:
Anti-UFD1L Rabbit Polyclonal Antibody
UOM:
1 * 50 µl
New Product
Numéro de catalogue:
(PRSI22-454)
Fournisseur:
ProSci Inc.
Description:
Anti-SMPD1 Rabbit Polyclonal Antibody
UOM:
1 * 50 µl
New Product
Numéro de catalogue:
(PRSI22-481)
Fournisseur:
ProSci Inc.
Description:
Anti-TSHR Rabbit Polyclonal Antibody
UOM:
1 * 50 µl
New Product
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