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Numéro de catalogue: (PRSIXA-1019)

Fournisseur:  ProSci Inc.
Description:   Anti-TNFSF13 Mouse Monoclonal Antibody
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI79-551)

Fournisseur:  ProSci Inc.
Description:   Converts transient diacylglycerol (DAG) signals into prolonged physiological effects, downstream of PKC. Involved in resistance to oxidative stress through activation of NF-κ-B.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSIXA-1009)

Fournisseur:  ProSci Inc.
Description:   Anti-PRF1 Mouse Monoclonal Antibody
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI79-553)

Fournisseur:  ProSci Inc.
Description:   NMDA receptors are members of the ionotropic class of glutamate receptors, which also includes Kainate and AMPA receptors. NMDA receptors consist of NR1 subunits combined with one or more NR2 (A-D) or NR3 (A-B) subunits. The ligand-gated channel is permeable to cations including Ca2+, and at resting membrane potentials NMDA receptors are inactive due to a voltage-dependent blockade of the channel pore by Mg2+. NMDA receptor activation, which requires binding of glutamate and glycine, leads to an influx of Ca2+ into the postsynaptic region where it activates several signaling cascades, including pathways leading to the induction of long-term potentiation (LTP) and depression (LTD). NMDA receptors have a critical role in excitatory synaptic transmission and plasticity in the CNS. They govern a range of physiological conditions including neurological disorders caused by excitotoxic neuronal injury, psychiatric disorders and neuropathic pain syndromes.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI29-599)

Fournisseur:  ProSci Inc.
Description:   This enzyme condenses acetyl-CoA with acetoacetyl-CoA to form HMG-CoA, which is the substrate for HMG-CoA reductase.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI29-582)

Fournisseur:  ProSci Inc.
Description:   Epithelial membrane protein-2 (EMP2) is a member of the four transmembrane superfamily (TM4SF) and is thought to mediate trafficking of diverse proteins such as alpha6beta1 integrin and MHC class I to lipid raft microdomains. EMP2 has also recently been recognized as a putative tumor suppressor gene in certain model systems.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI91-844)

Fournisseur:  ProSci Inc.
Description:   Pregnancy-specific beta-1-glycoprotein 5, is a secreted protein which belongs to the immunoglobulin superfamily, CEA family. It contains 2 Ig-like C2-type (immunoglobulin-like) domains and 1 Ig-like V-type (immunoglobulin-like) domain.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI29-400)

Fournisseur:  ProSci Inc.
Description:   U1SNRNPBP is a homolog of U1-snRNP binding protein. Its N-terminal half contains a RNA recognition motif and the C-terminal half is rich in Arg/Asp and Arg/Glu dipeptides, a characteristic of a variety of splicing factors.The protein encoded by this gene is a homolog of U1-snRNP binding protein. Its N-terminal half contains a RNA recognition motif and the C-terminal half is rich in Arg/Asp and Arg/Glu dipeptides, a characteristic of a variety of splicing factors. This gene is differentially expressed in a variety of human tissues. Multiple alternatively spliced transcript variants have been found for this gene, and they differ in the 5' sequence regions.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI45-758)

Fournisseur:  ProSci Inc.
Description:   Anti-ICAM5 Goat Polyclonal Antibody
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI45-761)

Fournisseur:  ProSci Inc.
Description:   Anti-IER5 Goat Polyclonal Antibody
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI92-273)

Fournisseur:  ProSci Inc.
Description:   Annexin A3(ANXA3)contains 4 annexin repeats and belongs to the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. It is abnormally expressed in fetuses of both IVF and ICSI, which may contribute to the increase risk of birth defects in these ART. ANXA3 is Inhibitor of phospholipase A2 and cleaves the cyclic bond of inositol 1,2-cyclic phosphate to form inositol 1-phosphate. it also also play a role in anti-coagulant properties.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI29-837)

Fournisseur:  ProSci Inc.
Description:   FBXO25 is a member of the F-box protein family which is characterized by an approximately 40 amino acid motif, the F-box. The F-box proteins constitute one of the four subunits of ubiquitin protein ligase complex called SCFs (SKP1-cullin-F-box), which function in phosphorylation-dependent ubiquitination. The F-box proteins are divided into 3 classes: Fbws containing WD-40 domains, Fbls containing leucine-rich repeats, and Fbxs containing either different protein-protein interaction modules or no recognizable motifs. FBXO25 belongs to the Fbxs class.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI29-840)

Fournisseur:  ProSci Inc.
Description:   The Makorin ring finger protein-1 gene (MKRN1) is a highly transcribed, intron-containing source for a family of intronless mammalian genes encoding a novel class of zinc finger proteins. Phylogenetic analyses indicate that the MKRN1 gene is the ancestral founder of this gene family.The modification of proteins with ubiquitin is an important cellular mechanism for targeting abnormal or short-lived proteins for degradation. Ubiquitination involves at least three classes of enzymes: ubiquitin-activating enzymes, or E1s, ubiquitin-conjugating enzymes, or E2s, and ubiquitin-protein ligases, or E3s. This gene encodes a member of the E2 ubiquitin-conjugating enzyme family. This enzyme is closely related to a stimulator of iron transport (SFT), and is up-regulated in hereditary hemochromatosis. It also functions in the ubiquitination of the tumor-suppressor protein p53 and the hypoxia-inducible transcription factor HIF1alpha by interacting with the E1 ubiquitin-activating enzyme and the E3 ubiquitin-protein ligases.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI29-832)

Fournisseur:  ProSci Inc.
Description:   C20orf18 is similar to mouse UIP28/UbcM4 interacting protein.The protein encoded by this gene is similar to mouse UIP28/UbcM4 interacting protein. Alternative splicing has been observed at this locus, resulting in distinct isoforms.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI29-843)

Fournisseur:  ProSci Inc.
Description:   PRPF19 plays a role in DNA double-strand break (DSB) repair and pre-mRNA splicing reaction. It binds double-stranded DNA in a sequence-nonspecific manner. PRPF19 acts as a structural component of the nuclear framework. It may also serve as a support for spliceosome binding and activity. It is essential for spliceosome assembly in a oligomerization-dependent manner and might also be important for spliceosome stability. It also may have E3 ubiquitin ligase activity. The PSO4 complex is required in the DNA interstrand cross-links (ICLs) repair process. Overexpression of PRPF19 might extend the cellular life span by increasing the resistance to stress or by improving the DNA repair capacity of the cells.In S. cerevisiae, Pso4 has pleiotropic functions in DNA recombination and in error-prone nonhomologous end-joining DNA repair.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI42-504)

Fournisseur:  ProSci Inc.
Description:   Anti-RSL1D1 Goat Polyclonal Antibody
UOM:  1 * 1 EA
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