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Numéro de catalogue: (PRSI1137)

Fournisseur:  ProSci Inc.
Description:   GFR alpha 3 Antibody: Members of the glial cell line-derived neurotrophic factor (GDNF) family, including GDNF and neurturin (NTN) play essential roles in the control of vertebrate neuron survival and differentiation. A new member of the GDNF family was recently identified and designated persephin. Physiological responses to these neurotrophic factors require two receptor subunits, the novel glycosylphosphadidylinositol linked protein GFR alpha and Ret receptor tyrosine kinase GFRbeta. Following the findings of GFR alpha -1 and -2, a novel receptor in GFR alpha family was identified very recently from human and mouse and designated GFR alpha -3. GFR alpha -3 binds persephin, thus, persephin, GFR alpha -3, and Ret PTK form a complex to transduce persephin signal and to mediate persephin function.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI25-362)

Fournisseur:  ProSci Inc.
Description:   The specific function of DDX59 is not yet known.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI25-351)

Fournisseur:  ProSci Inc.
Description:   The A-kinase anchor proteins (AKAPs) are a group of structurally diverse proteins, which have the common function of binding to the regulatory subunit of protein kinase A (PKA) and confining the holoenzyme to discrete locations within the cell. AKAP1 is a member of the AKAP family. It binds to type I and type II regulatory subunits of PKA and anchors them to the mitochondrion. This protein is speculated to be involved in the cAMP-dependent signal transduction pathway and in directing RNA to a specific cellular compartment.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI25-355)

Fournisseur:  ProSci Inc.
Description:   RAD54B belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.The protein encoded by this gene belongs to the DEAD-like helicase superfamily. It shares similarity with Saccharomyces cerevisiae RAD54 and RDH54, both of which are involved in homologous recombination and repair of DNA. This protein binds to double-stranded DNA, and displays ATPase activity in the presence of DNA. This gene is highly expressed in testis and spleen, which suggests active roles in meiotic and mitotic recombination. Homozygous mutations of this gene were observed in primary lymphoma and colon cancer.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI35-654)

Fournisseur:  ProSci Inc.
Description:   Anti-Helicobacter pylori Mouse Monoclonal Antibody
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI35-643)

Fournisseur:  ProSci Inc.
Description:   Anti-Salmonella Mouse Monoclonal Antibody
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI25-273)

Fournisseur:  ProSci Inc.
Description:   HOXB2 is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. HOXB2 functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with pancreatic cancer.This gene is a member of the Antp homeobox family and encodes a nuclear protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox B genes located on chromosome 17. The encoded protein functions as a sequence-specific transcription factor that is involved in development. Increased expression of this gene is associated with pancreatic cancer. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI25-286)

Fournisseur:  ProSci Inc.
Description:   ZNF234 may be involved in transcriptional regulation.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI31-136)

Fournisseur:  ProSci Inc.
Description:   Localized to biosynthetic and endosomal compartments, Rab14 is involved in the biosynthetic/recycling pathway between the Golgi and endosomal compartments.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI31-137)

Fournisseur:  ProSci Inc.
Description:   TRH functions as a regulator of the biosynthesis of TSH in the anterior pituitary gland and as a neurotransmitter/ neuromodulator in the central and peripheral nervous systems.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI31-133)

Fournisseur:  ProSci Inc.
Description:   Snap25 contains 2 t-SNARE coiled-coil homology domains and belongs to the SNAP-25 family. t-SNARE involved in the molecular regulation of neurotransmitter release. Snap25 may play an important role in the synaptic function of specific neuronal systems. Snap25 associates with proteins involved in vesicle docking and membrane fusion.
UOM:  1 * 50 µG
Numéro de catalogue: (PRSI31-135)

Fournisseur:  ProSci Inc.
Description:   TRHR is a receptor for thyrotropin-releasing hormone. This receptor is mediated by G proteins which activate a phosphatidylinositol-calcium second messenger system.
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI43-027)

Fournisseur:  ProSci Inc.
Description:   Anti-BRWD1 Goat Polyclonal Antibody
UOM:  1 * 1 EA
Numéro de catalogue: (PRSI31-127)

Fournisseur:  ProSci Inc.
Description:   After binding acetylcholine, the ACHR responds by an extensive change in conformation that affects all subunits and leads to opening of an ion-conducting channel across the plasma membrane.
UOM:  1 * 1 EA

Fournisseur:  ProSci Inc.
Description:   Aminoglycoside 3'-phosphotransferase (APH(3')), also known as aminoglycoside kinase, is an aminoglycoside-modifying enzyme and widely presented in resistant bacteria. These ATP-dependent enzymes phosphorylate the 3'-hydroxyl of a variety of aminoglycosides including kanamycins, neomycins, paromomycins, neamine, ribostamycin, geneticin, and paromamine. These phosphorylated aminoglycosides fail to bind to their respective ribosomal binding sites with high affinity; hence resistance is conferred to the drugs that are phosphorylated. APH(3') is primarily found in certain species of gram-positive bacteria.
UOM:  1 * 50 µG

Fournisseur:  ProSci Inc.
Description:   Phosphinothricin N-acetyltransferase (PAT) is an enzyme that acetylates the free NH2 group of L-phosphinothricin (L-PPT) in the presence of acetyl-CoA as a co-substrate. It is highly specific for L-PPT and does not acetylate other L-amino acids or structurally similar molecules. L-PPT is a glutamate analog that can inhibit glutamine synthetase activity in plants, resulting in the accumulation of ammonia to toxic levels and impairment of photosynthesis. The introduction of a PAT gene into a plant genome can confer resistance to glufosinate herbicide during post-emergent applications.
UOM:  1 * 50 µG
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