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ProSci Inc.
Numéro de catalogue:
(PRSI92-268)
Fournisseur:
ProSci Inc.
Description:
Apolipoprotein A1 (APOA1) is a secreted protein which belongs to the Apolipoprotein A1/A4/E family. APOA1 is the major protein component of high density lipoprotein (HDL) in plasma. APOA1 plays a critical role in various biological processes, such as Cholesterol metabolism, Lipid metabolism and transport, Steroid metabolism. APOA1 promotes cholesterol efflux from tissues to the liver and thus helps to clear cholesterol from arteries. Defects in this gene resulted in HDL deficiencies, including Tangier disease (TGD), systemic non-neuropathic amyloidosis, premature coronary artery disease, hepatosplenomegaly and progressive muscle wasting and weakness. In addition, ApoA-I is implicated in the anti-endotoxin function of HDL via interaction with lipopolysaccharide or endotoxin.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI45-745)
Fournisseur:
ProSci Inc.
Description:
Anti-HPS9 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI45-760)
Fournisseur:
ProSci Inc.
Description:
Anti-IDE Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI45-763)
Fournisseur:
ProSci Inc.
Description:
Anti-IGFBP4 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI45-746)
Fournisseur:
ProSci Inc.
Description:
Anti-HGS Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI45-753)
Fournisseur:
ProSci Inc.
Description:
Anti-TNFRSF14 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI38-134)
Fournisseur:
ProSci Inc.
Description:
A novel cytokine related to IL2 and IL15 was recently identified and designated IL21. IL21 has been found to be a powerful growth factor for naive B cells. The receptor for IL21 (IL21R, also termed NILR for novel Interleukin receptor) is a new member of the class I cytokine receptor family. IL21R forms a complex with the common cytokine receptor g chain, gc, and mediates IL21 signaling. Both IL21R and the gc are necessary for the IL21 function. IL21 and its receptor activate JAKSTAT signaling pathway. IL21R is expressed in spleen, thymus, natural killer (NK), T and B cell lines. IL21 plays a role in the proliferation and maturation of NK, B and T cell populations.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI92-270)
Fournisseur:
ProSci Inc.
Description:
Krueppel-Like Factor 6 (KLF6) belongs to the krueppel C2H2-type zinc-finger protein family. KLF6 contains three C2H2-type zinc fingers and localises in the nucleus. KLF6 expression is highest in the placenta followed by spleen, thymus, prostate, testis, small intestinem and colon. However, it is weakly expressed in the pancreas, lung, liver, heart, and skeletal muscle. KLF6 functions as a transcriptional activator and could play a role in B-cell growth and development. Defects in KLF6 will result in gastric cancer and prostate cancer.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-706)
Fournisseur:
ProSci Inc.
Description:
Leucine-Rich Repeat Transmembrane Protein FLRT3 (FLRT3) is a member of the fibronectin leucine rich transmembrane protein (FLRT) family. Proteins in this family play an role in cell adhesion and/or receptor signalling. FLRT3 is a single-pass type I membrane protein and contains one fibronectin type-III domain, ten LRR (leucine-rich) repeats, one LRRCT domain, and one LRRNT domain. FLRT3 may have a function in cell adhesion and/or receptor signaling. FLRT3 may regulate cellular adhesion between the epithelial apical ridge and the underlying mesenchyme and in establishing the dorso-ventral position of the ridge.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI26-171)
Fournisseur:
ProSci Inc.
Description:
GALNT6 is a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. GALNT6 is capable of glycosylating fibronectin peptide in vitro and is expressed in a fibroblast cell line, indicating that it may be involved in the synthesis of oncofetal fibronectin.This gene encodes a member of the UDP-N-acetyl-alpha-D-galactosamine:polypeptide N-acetylgalactosaminyltransferase (GalNAc-T) family of enzymes. GalNAc-Ts initiate mucin-type O-linked glycosylation in the Golgi apparatus by catalyzing the transfer of GalNAc to serine and threonine residues on target proteins. They are characterized by an N-terminal transmembrane domain, a stem region, a lumenal catalytic domain containing a GT1 motif and Gal/GalNAc transferase motif, and a C-terminal ricin/lectin-like domain. GalNAc-Ts have different, but overlapping, substrate specificities and patterns of expression. The encoded protein is capable of glycosylating fibronectin peptide in vitro and is expressed in a fibroblast cell line, indicating that it may be involved in the synthesis of oncofetal fibronectin. PRIMARYREFSEQ_SPAN PRIMARY_IDENTIFIER PRIMARY_SPAN COMP 1-3 BC035822.1 1-3 4-130 DB001644.1 179-305 131-2654 BC035822.1 134-2657 2655-4520 AC046135.15 108099-109964 c
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5101P)
Fournisseur:
ProSci Inc.
Description:
CDC42 peptide is used for blocking the activity of CDC42 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5073P)
Fournisseur:
ProSci Inc.
Description:
LZTS2 peptide is used for blocking the activity of LZTS2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI29-962)
Fournisseur:
ProSci Inc.
Description:
SLC26A5 is a member of the SLC26A/SulP transporter family. SLC26A5 is specifically expressed in outer hair cells (OHCs) of the cochlea and is essential in auditory processing. Intracellular anions are thought to act as extrinsic voltage sensors, which bind to this protein and trigger the conformational changes required for rapid length changes in OHCs. Mutations in its gene have been associated with non-syndromic hearing loss.This gene is a member of the SLC26A/SulP transporter family. It encodes a protein that is specifically expressed in outer hair cells (OHCs) of the cochlea and is essential in auditory processing. Intracellular anions are thought to act as extrinsic voltage sensors, which bind to this protein and trigger the conformational changes required for rapid length changes in OHCs. Mutations in this gene have been associated with non-syndromic hearing loss. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI42-593)
Fournisseur:
ProSci Inc.
Description:
Anti-CUL2 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI28-471)
Fournisseur:
ProSci Inc.
Description:
ZNF227 is a new candidate transcription factor.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI28-470)
Fournisseur:
ProSci Inc.
Description:
ZNF227 is a new candidate transcription factor.
UOM:
1 * 50 µG
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