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STEMCELL Technologies
Numéro de catalogue:
(STMC100-0673)
Fournisseur:
STEMCELL Technologies
Description:
HBV (HLA Class I Control) Peptide pool is a lyophilised mixture of 9 peptides from the hepatitis B virus (HBV). The pool consists of defined HLA class I-restricted T cell epitopes, and can be used as an antigen-specific positive control to stimulate T cells.
UOM:
1 * 1 Kit
 Il s'agit d'un élément MarketSource. Des frais supplémentaires peuvent s'appliquer.
Fournisseur:
STEMCELL Technologies
Description:
Mouse monoclonal IgG1 antibody against human angiotensin-converting enzyme 2 (ACE2).
Fournisseur:
STEMCELL Technologies
Description:
Mouse monoclonal IgG2a, antibody against human, rhesus, cynomolgus HLA-DR, FITC-conjugated.
Fournisseur:
STEMCELL Technologies
Description:
Mouse monoclonal IgG1, antibody against human, chimpanzee CD4, PE-conjugated.
Numéro de catalogue:
(STMC100-0287)
Fournisseur:
STEMCELL Technologies
Description:
Mouse monoclonal IgG2a, antibody against human CD3, unconjugated.
UOM:
1 * 1 EA
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Fournisseur:
STEMCELL Technologies
Description:
Fibroblast growth factor 8B (FGF-8B) is a member of the fibroblast growth factor (FGF) family and is an isoform of FGF-8. Cytokines in the FGF family possess broad mitogenic and cell survival activities (Folkman and Klagsbrun; Kimelman and Kirschner) and are involved in a variety of biological processes, including cell proliferation, differentiation, survival, and apoptosis (Folkman and Klagsbrun; Klagsbrun; Rifkin and Moscatelli). FGF-8B signals through FGF receptors (FGFRs) to activate PI3K and MAPK pathways. FGF-8B regulates gastrulation, epithelial-mesenchymal transition, and mesenchymal to epithelial differentiation during embryonic development. FGF-8B has also been found in peripheral blood leukocytes and healthy bone marrow samples (Mattila and Härkönen). FGF-8B has mitogenic effects on somatic cells in the germinal epithelium and is expressed in adult mouse ovarian cells and tissues, which suggests that it regulates maturation of oocytes and seminiferous epithelium in testes (Valve <i>et al.</i>). This product is animal component-free.
Fournisseur:
STEMCELL Technologies
Description:
Fibroblast growth factor 7 (FGF-7) is a member of the FGF family, and acts exclusively through a subset of FGF receptor isoforms expressed predominantly by epithelial cells (Finch and Rubin). FGF-7 seems to act specifically on epithelial cells and stimulates proliferation, migration, and differentiation of these cells, and also participates in epithelial protection and repair both in vitro and in vivo (Finch and Rubin; Werner). In contrast, FGF-7 is produced solely by cells of mesenchymal origin, and functions as a paracrine mediator of mesenchymal-epithelial communication (Rubin <i>et al.</i>). FGF-7 has also been shown to supplement several wound-healing properties of bioengineered skin (Erdag <i>et al.</i>) and to induce autophagy in human keratinocytes (Belleudi <i>et al.</i>). Additionally, FGF-7 has a role in the differentiation of pluripotent stem cell to endodermal pancreatic-like insulin-producing cells and thymic epithelial cells (Inami <i>et al.</i>; Niu <i>et al.</i>). This product is animal component-free.
Fournisseur:
STEMCELL Technologies
Description:
Animal component-free and protein-free cryopreservation formulation.
Numéro de catalogue:
(STMC100-0993)
Fournisseur:
STEMCELL Technologies
Description:
Fluorescent lipophilic dye used to quantify mitochondrial membrane potential and assess cell viability.
UOM:
1 * 5 mg
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Numéro de catalogue:
(STMC100-0781)
Fournisseur:
STEMCELL Technologies
Description:
Culture medium kit for growth, and establishment of human pancreatic organoids.
UOM:
1 * 1 Kit
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Numéro de catalogue:
(STMC100-0847)
Fournisseur:
STEMCELL Technologies
Description:
Cell culture medium for passaging and long-term expansion of human alveolar epithelial type II (ATII) cells as organoids.
UOM:
1 * 1 Kit
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Numéro de catalogue:
(STMC100-0991)
Fournisseur:
STEMCELL Technologies
Description:
Sensitive fluorescent dye that detects superoxide production in mitochondria - 500 tests.
UOM:
1 * 500 ST
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Fournisseur:
STEMCELL Technologies
Description:
Hamster (Armenian) monoclonal IgG, antibody against mouse, CD152 (CTLA-4), PE-conjugated.
Fournisseur:
STEMCELL Technologies
Description:
Dickkopf-related protein 1 (DKK-1) is a member of the Dickkopf family and is a secreted protein that inhibits the canonical WNT pathway by competitive binding to low-density lipoprotein receptors (LRP)-5 and 6 with high affinity, thereby decreasing β-catenin protein stability (Niehrs). DKK-1 regulates embryonic development and contains two conserved cysteine-rich domains separated by a linker region and an N-terminal signal peptide (Krupnik <i>et al.</i>; Lieven <i>et al.</i>). A family of human DKK-related genes composed of DKK-1, DKK-2, DKK-3, and DKK-4 have been characterized together with a unique DKK-3 related protein termed Soggy (Krupnik <i>et al.</i>). DKK-1 has been shown to support the generation of myeloid-derived suppressor cells (MDSCs) and thus is a negative regulator of antitumor immune responses (D’Amico <i>et al.</i>). DKK-1 from thrombocytes is an important regulator of leukocyte infiltration and induces Th2 cell polarization and potentiates Th2 cell cytokine expression (Chae <i>et al.</i>). DKK-1 has also been shown to drive cardiac and retinal differentiation from induced pluripotent stem (iPS) cells (Lian <i>et al.</i>). Protein contains a His-residue tag at the carboxyl end of the polypeptide chain.
Numéro de catalogue:
(STMC100-0318)
Fournisseur:
STEMCELL Technologies
Description:
Mouse monoclonal IgG2b, antibody against human, chimpanzee, CD45RA, PE-conjugated.
UOM:
1 * 1 EA
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Fournisseur:
STEMCELL Technologies
Description:
SARS-CoV-2 Recombinant Spike Protein, aa319-541 is expressed in <i>Pichia pastoris</i> and is one of four structural proteins encoded by the SARS-CoV-2 genome. The Spike Protein plays a key role in attachment to host cells allowing invasion through clathrin-mediated endocytosis. The spike protein can be cleaved by host cell proteases after aa685 to yield the N-terminal S1 subunit, and C-terminal S2 region. The S1 subunit is responsible for interacting with the host cell receptor (angiotensin-converting enzyme II) through a receptor-binding domain that is highly conserved with SARS-CoV. The S1 subunit has two conformations: a ‘down’ conformation in which the receptor is inaccessible, and an ‘up’ conformation in which the receptor is accessible. These conformational changes are key for monoclonal antibody drugs and vaccine development. At the amino terminus of the polypeptide chain, SARS-CoV-2 Recombinant spike protein contains a polyhistidine tag and a SUMOstar site.
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