Imprimer
Votre recherche pour:
511 493 les résultats ont été trouvés
Anticorps
Numéro de catalogue:
(PRSI10-278)
Fournisseur:
ProSci Inc.
Description:
Anti-19.79.5 Recombinant Antibody
UOM:
1 * 0,1 mg
New Product
Numéro de catalogue:
(ENZOALX210638C200)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Host: Goat
UOM:
1 * 200 µG
New Product
Numéro de catalogue:
(ENZOALX210647C200)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Host: Goat
UOM:
1 * 200 µG
New Product
Numéro de catalogue:
(ENZOALX215035R100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Host: Rabbit
UOM:
1 * 100 µl
New Product
Numéro de catalogue:
(ENZOALX210950C100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Host: Rabbit
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(ENZOALX210932C100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
RIG-I (retinoic acid-inducible gene I; Ddx58), a member of the DEAD-box RNA helicases, is activated by cytoplasmic dsRNA and 5’-ppp RNA produced during the viral replication. The protein is characterized by a N-terminal region with two caspase recruitment domains (CARD) and a C-terminal region harboring potential ATP-dependent RNA helicase activity. RIG-1 recruits the CARD adaptor inducing IFN-β (Cardif) in a CARD-CARD-dependent manner resulting in NF-κB and IRF3 activation.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(ENZOALX2150651)
Fournisseur:
ENZO LIFE SCIENCES
Description:
mTOR (FKBP12-rapamycin associated protein (FRAP)) is one of a family of proteins involved in cell cycle progression, DNA recombination, and DNA damage detection. It has been shown to associate with the immunophilin FKBP12 in a rapamycin-dependent fashion. FKBP12-rapamycin-binding (FRB) domain is a conserved 11kDa region necessary for FKBP12-rapamycin binding. FRB is one of several functional domains of mTOR: HEAT (Huntington elongation factor 1A-protein phosphatase 2A-A subunit-TOR); FAT (FRAP, ATM, TTRAP2); PIKK (PI3-kinase-related kinase); RD (regulatory domain); and FATC (FAT, C terminal).
UOM:
1 * 1 VIA
New Product
Numéro de catalogue:
(ENZOALX804162C100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Host: Mouse, Isotype: IgM
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(ENZOALX804151FT100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Recommended Applications: Flow Cytometry
Species reactivity: Human
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(ENZOALX804240BC100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Host: Mouse, Isotype: IgG1
UOM:
1 * 1 EA
New Product
Fournisseur:
ENZO LIFE SCIENCES
Description:
Synuclein was originally identified in Torpedo californica as a small neuroprotein that localized to the nuclear envelope of neurons and to presynaptic nerve termini. The human homolog was initially termed NACP, a precursor protein to NAC (Non-Ab Component), because of its prevalence in amyloid plaques in Alzheimer’s patients. Later, NACP was recognized as being alpha-Synuclein (alpha-SYN), a 14kDa protein, belonging to the synuclein family of phosphoproteins that also includes: betalpha-SYNuclein, gammalpha-SYNuclein, and synoretin.
alpha-SYN is recognized as a key component in the development and diagnosis of neurodegenerative synucleinopathic diseases (NSDs), such as Alzheimer’s and Parkinson’s disease. In the past five years, several genetic and post-translational modifications to alpha-SYN have been elucidated that have been linked to its collaboration in the formation of the classical Lewy bodies (LBs) or Lewy neurites that are associated with neurodegeneration. A study that shed more light on the neurogenesis of autorecessive synucleinopathies (ARSs) was the finding that alpha-SYN accumulation can occur due to mutations in the E3 ubiquitin ligase. ARSs only account for a small percentage of NSD. Thus the illustration that alpha-SYN has a high susceptibility to tyrosine nitration may be the key component in understanding the formation of LBs. Due to the chemical structure of alpha-SYN, tyrosine nitration readily leads to the formation of oligomers via covalent O,O’-dityrosine bonds (cross-linking). Nitrosylated, wild-type, alpha-SYN products thus form SDS-insoluble, heat-stable aggregates in vitro that may account for alpha-SYN inclusions in all forms of NSDs.
Numéro de catalogue:
(ENZOALX804155C100)
Fournisseur:
ENZO LIFE SCIENCES
Description:
Certain serine/threonine protein kinases, such as ASK1, RIP, DAP, and ZIP kinases, are mediators of apoptosis. Receptor interacting proteins including RIP and RIP2/RICK mediate apoptosis induced by TNF-R1 and Fas, two prototype members in the death receptor family. A member in the RIP kinase family was identified and designated RIP3. RIP3 contains an N-terminal kinase domain but, unlike RIP or RIP2, lacks the C-terminal death or CARD domain. RIP3 binds to RIP and TNF-R1, mediates TNF-R1 induced apoptosis, and attenuates RIP and TNF-R1 induced NF-κB activation. Overexpression of RIP3 induces apoptosis and NF-κB activation. The messenger RNA of RIP3 is expressed in a subset of adult tissues. Meanwhile RIP4 has been identified and initially characterized. These data suggest that RIP4 is involved in NF-κB and JNK signalling and that caspase-dependent processing of RIP4 may negatively regulate NF-κB-dependent pro-survival or pro-inflammatory signals.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(PRSI10-334)
Fournisseur:
ProSci Inc.
Description:
Anti-MDX-1103 Recombinant Antibody
UOM:
1 * 0,1 mg
New Product
Numéro de catalogue:
(PRSI10-289)
Fournisseur:
ProSci Inc.
Description:
Anti-2D10 Recombinant Antibody
UOM:
1 * 0,1 mg
New Product
Numéro de catalogue:
(PRSI10-291)
Fournisseur:
ProSci Inc.
Description:
Anti-rhuMAb Recombinant Antibody
UOM:
1 * 0,1 mg
New Product
Numéro de catalogue:
(PRSI10-292)
Fournisseur:
ProSci Inc.
Description:
Anti-78NCA-90 Recombinant Antibody
UOM:
1 * 0,1 mg
New Product
Appel de prix
Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'
 est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
Le stock de cet article est limité mais peut être disponible dans un entrepôt proche de vous. Merci de vous assurer que vous êtes connecté sur le site afin que le stock disponible soit affiché. Si l'
est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
Ces articles ne peuvent être ajoutés au Panier. Veuillez contacter votre service client ou envoyer un e-mail à vwr.be@vwr.com
Une documentation supplémentaire peut être nécessaire pour l'achat de cet article. Un représentant de VWR vous contactera si nécessaire.
Ce produit a été bloqué par votre organisation. Contacter votre service d'achat pour plus d'informations.
Le produit original n'est plus disponible. Le remplacement représenté est disponible
Les produits marqués de ce symbole ne seront bientôt plus disponibles - vente jusqu'à épuisement de stock. Des alternatives peuvent être disponibles en recherchant le code article VWR indiqué ci-dessus. Si vous avez besoin d'une assistance supplémentaire, veuillez contacter notre Service Clientèle au 016 385 011.
|
|||||||||
Vue liste
