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Protéines et Peptides
Numéro de catalogue:
(PRSI5633P)
Fournisseur:
ProSci Inc.
Description:
DCLK1 pepide is used for blocking the activity of DCLK1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3173P)
Fournisseur:
ProSci Inc.
Description:
TRIF peptide is used for blocking the activity of the TRIF antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-404)
Fournisseur:
ProSci Inc.
Description:
Carcinoembryonic Antigen-Related Cell Adhesion Molecule 1 (CEACAM1) is a member of the Carcinoembryonic Antigen (CEA) family, which belongs to the immunoglobulin superfamily. CEACAM1 is originally described in bile ducts of liver as biliary glycoprotein. Subsequently, it is found to be a cell-cell adhesion molecule detected on leukocytes, epithelia, and endothelia. CEACAM1 mediates cell adhesion via homophilic as well as heterophilic binding to other proteins of the subgroup. In addition, CEACAM1 plays a important role in the differentiation and arrangement of tissue three-dimensional structure, angiogenesis, apoptosis, tumor suppression, metastasis, and the modulation of innate and adaptive immune responses.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3337P)
Fournisseur:
ProSci Inc.
Description:
Bcl-2 peptide is used for blocking the activity of Bcl-2 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI3321P)
Fournisseur:
ProSci Inc.
Description:
PIKE peptide is used for blocking the activity of Anit-PIKE antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI5625P)
Fournisseur:
ProSci Inc.
Description:
BCAS1 pepide is used for blocking the activity of BCAS1 antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-400)
Fournisseur:
ProSci Inc.
Description:
Fc gamma RIIB is a low affinity receptor that recognizes the Fc portion of IgG. The human CD32 group consists of Fc gamma RIIA, Fc gamma RIIB, and Fc gamma RIIC proteins that share 94-99% sequence identity in their extracellular domains but differ substantially in their transmembrane and cytoplasmic domains. Fc gamma RII protein is expressed on cells of both myeloid and lymphoid lineages as well as on cells of non-hematopoietic origin. Fc gamma RIIB has an intrinsic cytoplasmic immunoreceptor tyrosine-based inhibitory motif (ITIM) and delivers an inhibitory signal upon ligand binding. Ligation of Fc gamma RIIB on B cells down-regulates antibody production and in some circumstances may promote apoptosis. Co-ligation of Fc gamma RIIB on dendritic cells inhibits maturation and blocks cell activation. Fc gamma RIIB may also be a target for monoclonal antibody therapy for malignancies. Fc gamma RIIB plays an important negative-regulating role through modulating the signals from activation receptors.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6025P)
Fournisseur:
ProSci Inc.
Description:
MFSD2A peptide is used for blocking the activity of MFSD2A antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-798)
Fournisseur:
ProSci Inc.
Description:
Activin Receptor Type-2A is a protein that in humans is encoded by the ACVR2A gene. ACVR2A is an activin type 2 receptor. This gene encodes activin A type II receptor. Activins are dimeric growth and differentiation factors which belong to the transforming growth factor-beta (TGF-beta) superfamily of structurally related signaling proteins. Activins signal through a heteromeric complex of receptor serine kinases which include at least two type I (I and IB) and two type II (II and IIB) receptors. These receptors are all transmembrane proteins, composed of a ligand-binding extracellular domain with cysteine-rich region, a transmembrane domain, and a cytoplasmic domain with predicted serine/threonine specificity. Type I receptors are essential for signaling; and type II receptors are required for binding ligands and for expression of type I receptors. Type I and II receptors form a stable complex after ligand binding, resulting in phosphorylation of type I receptors by type II receptors. Type II receptors are considered to be constitutively active kinases.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI6027P)
Fournisseur:
ProSci Inc.
Description:
MFSD2B peptide is used for blocking the activity of MFSD2B antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI4033P)
Fournisseur:
ProSci Inc.
Description:
DRAM peptide is used for blocking the activity of DRAM antibody.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-121)
Fournisseur:
ProSci Inc.
Description:
Fatty Acid-Binding Protein 7 (FABP7) is a cytoplasm protein that belongs to the Fatty-acid Binding Protein (FABP) family of calycin superfamily. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids. FABP7 is predominately expressed in brain and neural tissues. FABP7 is involved in fatty acid uptake and intracellular transport and is important in brain development. FABP7 plays a critical role in the transport of a so far unknown hydrophobic ligand with potential morphogenic activity during CNS development. FABP7 is required for the establishment of the radial glial fiber system in developing brain, a system that is necessary for the migration of immature neurons to establish cortical layers.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-126)
Fournisseur:
ProSci Inc.
Description:
Grancalcin (GCA) is a member of the penta EF hand subfamily which includes sorcin, calpain and ALG2. Grancalcin is highly expressed bone marrow and also can detected in neutrophils and macrophages. Grancalcin interacts with L-plastin which known to have actin bundling activity. It indicates that Grancalcin may play an important role in the adhesion of neutrophils to fibronectin. Furthermore, Grancalcin localization is dependent upon calcium and magnesium. It associates with both the granule and membrane fractions, which suggested a role for grancalcin in granule-membrane fusion and degranulation.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-117)
Fournisseur:
ProSci Inc.
Description:
Fatty Acid-Binding Protein 2 (FABP2) is a cytoplasm protein that belongs to the Fatty-acid binding protein (FABP) family of calycin superfamily. Fatty acid binding proteins are a family of small, highly conserved, cytoplasmic proteins that bind long-chain fatty acids. FABP2 is expressed in the small intestine and at much lower levels in the large intestine, the highest expression levels in the jejunum. FABP2 binds saturated long-chain fatty acids with a high affinity, but binds with a lower affinity to unsaturated long-chain fatty acids. FABP2 is probably involved in triglyceride-rich lipoprotein synthesis and may also help maintain energy homeostasis by functioning as a lipid sensor.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-068)
Fournisseur:
ProSci Inc.
Description:
Tumor necrosis factor alpha (TNF alpha) is the prototypic ligand of the TNF superfamily. TNF alpha forms a homotrimer and functions by activating two types of receptors TNF-R1 (TNF receptor type 1,p55R) and TNF-R2 (TNF receptor type 2,p75R). TNF alpha is a pleiotropic cytokine that is capable to promote inflammation, to induce apoptotic cell death, and to inhibit tumorigenesis and viral replication. TNF alpha is a potent lymphoid factor that exerts cytotoxic effects on a wide range of tumor cells and certain other target cells.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI91-069)
Fournisseur:
ProSci Inc.
Description:
Human Vascular endothelial growth factor (VEGF), also known as VEGF-A and vascular permeability factor (VPF), belongs to the platelet-derived growth factor family of cysteine-knot growth factors. It is a potent activator in vasculogenesis and angiogenesis both physiologically and pathologically. VEGF-A has 8 differently spliced isoforms, of which VEGF165 is the most abundant one. VEGF165 is a disulfide-linked homodimer consisting of two glycosylated 165 amino acid polypeptide chains. VEGF stimulates the cellular response through binding to tyrosine kinase receptors VEGFR1 and VEGFR2 on the cell surface. It is widely accepted that VEGFR2 mediate almost all of the known cellular responses to VEGF while the function of VEGFR1 is less defined and is thought to modulate the VEGFR2 signaling.
UOM:
1 * 50 µG
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