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Antilichamen
Leverancier:
Biotium
Omschrijving:
This MAb is specific to heavy chain of IgA and shows minimal cross-reaction with heavy chains of other immunoglobulins. It is reactive with both IgA1 and IgA2 subclasses of Alpha heavy chain. It reacts with the third constant domain (CH3) of the alpha chain of IgA molecules. Immunoglobulins are four-chain, Y-shaped, monomeric structures comprised of two identical heavy chains and two identical light chains held together through inter-chain disulfide bonds. The chains form two domains, the Fab (antigen binding) fragment and the Fc (constant) fragment. Immunoglobulin A (IgA) is the main protein of the mucosal immune system. It is generated by B-cells in gut-associated lymphoid tissues. Daily production of IgA exceeds that of any of the other immunoglobulins.IgA exists mainly in dimers but can also exist as polymers or as monomers. Dimers and polymers contain a joining (J) chain that can be bound by the polymeric immunoglobulin receptor (pIgR) for transportation of the molecule to mucosal surfaces. The most common feature of plasmacytomas, and certain non-Hodgkin's lymphomas is the restricted expression of a single heavy chain class. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is clonal and therefore malignant.
Leverancier:
Biotium
Omschrijving:
This MAb is specific to c-erbB-2/HER-2 and shows minimal cross-reaction with other members of the family. C-erbB-2/HER-2 is a member of the EGFR family. Receptors of this family are located on the plasma membrane and consist of an extracellular ligand-binding domain that is connected to a large intracellular domain by a single transmembrane sequence. c-erbB-2/HER-2 protein is over-expressed in a variety of carcinomas especially those of breast and ovary.
Leverancier:
Biotium
Omschrijving:
This antibody recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
Leverancier:
Biotium
Omschrijving:
This antibody recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
Leverancier:
Biotium
Omschrijving:
This antibody recognizes a polypeptide which is identified as insulin, a 51-amino acid polypeptide composed of A and B chains connected through the C-peptide. Proinsulin, which has very little biological activity, is cleaved by proteases within its cell of origin into the insulin molecule and the C-terminal basic residue. Insulin enhances membrane transport of glucose, amino acids, and certain ions. It also promotes glycogen storage, formation of triglycerides, and synthesis of proteins and nucleic acids. Deficiency of insulin results in diabetes mellitus. The main storage site for insulin is the pancreatic islets. Antibodies to insulin are important as beta-cell and insulinoma marker.
Itemnummer:
(BNUM0792-50)
Leverancier:
Biotium
Omschrijving:
This MAb reacts with a reduction-resistant epitope present in both free and SIgA bound Secretory Component. It does not react with the cell lines lacking secretory component. The antibody is useful for studying the distribution and level of both free and bound secretory component. Secretory component is differentially expressed in epithelium, and the antibody is a popular marker for identifying subpopulations of epithelial cells and epithelial differentiation. The Secretory component antibody is a useful research tool for studying mucosal immunity, inflammation, remodeling, differentiation and tumorigenesis, all processes associated with differential secretory component expression.
UOM:
1 * 50 µl
Itemnummer:
(USBIG3900-50D)
Leverancier:
US Biological
Omschrijving:
Anti-GLUT 4 Rabbit Polyclonal Antibody
UOM:
1 * 100 µl
Itemnummer:
(USBIG3900-50G)
Leverancier:
US Biological
Omschrijving:
Anti-GLUT 4 Mouse Monoclonal Antibody [clone: 10C380]
UOM:
1 * 50 µG
Itemnummer:
(USBIG3900-50M)
Leverancier:
US Biological
Omschrijving:
Anti-GLUT4/SLC2A4 Goat Polyclonal Antibody
UOM:
1 * 1 EA
Itemnummer:
(USBI039764-BIOTIN)
Leverancier:
US Biological
Omschrijving:
Anti-PCIA1 Rabbit Polyclonal Antibody (Biotin)
UOM:
1 * 200 µl
Itemnummer:
(USBI039756-BIOTIN)
Leverancier:
US Biological
Omschrijving:
Anti-PCDHGB1 Rabbit Polyclonal Antibody (Biotin)
UOM:
1 * 200 µl
Itemnummer:
(AVIVARP55838_P050)
Leverancier:
Aviva Systems Biology
Omschrijving:
Anti-FAM131C Rabbit Polyclonal Antibody
UOM:
1 * 50 µG
Itemnummer:
(AVIVARP55780_P050)
Leverancier:
Aviva Systems Biology
Omschrijving:
Anti-C2orf53 Rabbit Polyclonal Antibody
UOM:
1 * 50 µG
Itemnummer:
(AVIVARP59491_P050)
Leverancier:
Aviva Systems Biology
Omschrijving:
Anti-ERC1 Rabbit Polyclonal Antibody
UOM:
1 * 50 µG
Itemnummer:
(AVIVARP59494_P050)
Leverancier:
Aviva Systems Biology
Omschrijving:
Anti-MLPH Rabbit Polyclonal Antibody
UOM:
1 * 50 µG
Itemnummer:
(AVIVARP55797_P050)
Leverancier:
Aviva Systems Biology
Omschrijving:
Anti-TMCO4 Rabbit Polyclonal Antibody
UOM:
1 * 50 µG
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 nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11.
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
Dit product is gemarkeerd als beperkt en kan enkel gekocht worden door goedgekeurde verzendingsaccounts. Als u hulp nodig heeft gelieve dan het VWR-Regelgevend Departement te contacteren via regulatory_affairs@vwr.com.
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