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Antilichamen
Itemnummer:
(USBI149876)
Leverancier:
US Biological
Omschrijving:
Anti-HCAR1 Goat Polyclonal Antibody [clone: NP_115943.1]
UOM:
1 * 1 EA
Leverancier:
Biotium
Omschrijving:
Recognizes a protein of 205 kDa, which is identified as integrin beta-4 (ITGB4). Its epitope is localized in the extracellular domain of ITGB4 protein. Integrins are heterodimers comprised of alpha and beta subunits, that are non-covalently associated transmembrane glycoprotein receptors. Different combinations of alpha and beta polypeptides form complexes that vary in their ligand-binding specificities. Integrins mediate cell-matrix or cell-cell adhesion, and transduced signals that regulate gene expression and cell growth. This gene encodes the integrin beta-4 subunit, a receptor for the laminins. This subunit tends to associate with alpha-6 subunit and is likely to play a pivotal role in the biology of invasive carcinoma. Mutations in this gene are associated with epidermolysis bullosa with pyloric atresia. Multiple alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
Leverancier:
Biotium
Omschrijving:
Recognizes a protein of 110 kDa, identified as CD106 (also known as vascular cell adhesion molecule-1 (VCAM-1) and INCAM-100). CD106 is a member of the Ig superfamily of adhesion molecules and is expressed at high levels on cytokine stimulated vascular endothelial cells, and at minimal levels on un-stimulated endothelial cells. It is also present on follicular and inter-follicular dendritic cells of lymph nodes, myoblasts, and some macrophages. CD106 serves as a ligand for leukocyte integrin (VLA-4 or CD49d/CD29) and mediates cell adhesion of leukocytes to activated endothelium. It plays a role in various immunological and inflammatory responses.
Itemnummer:
(USBIM2871-60-APC)
Leverancier:
US Biological
Omschrijving:
Anti-MELK Rabbit Polyclonal Antibody (APC (Allophycocyanin))
UOM:
1 * 200 µl
Leverancier:
Biotium
Omschrijving:
This antibody recognizes a protein of 54 kDa, which is identified as AMACR, also known as p504S. It is an enzyme that is involved in bile acid biosynthesis and β-oxidation of branched-chain fatty acids. AMACR is essential in lipid metabolism. It is expressed in cells of premalignant high-grade prostatic intraepithelial neoplasia (HGPIN) and prostate adenocarcinoma. The majority of the carcinoma cells show a distinct granular cytoplasmic staining reaction. AMACR is present at low or undetectable levels in glandular epithelial cells of normal prostate and benign prostatic hyperplasia. A spotty granular cytoplasmic staining is seen in a few cells of the benign glands. AMACR is expressed in normal liver (hepatocytes), kidney (tubular epithelial cells) and gall bladder (epithelial cells). Expression has also been found in lung (bronchial epithelial cells) and colon (colonic surface epithelium). AMACR expression can also be found in hepatocellular carcinoma and kidney carcinoma. Past studies have also shown that AMACR is expressed in various colon carcinomas (well, moderately and poorly differentiated) and overexpressed in prostate carcinoma.
Itemnummer:
(USBIP3048-69-PE)
Leverancier:
US Biological
Omschrijving:
Anti-PANK1 Rabbit Polyclonal Antibody (PE (Phycoerythrin))
UOM:
1 * 200 µl
Itemnummer:
(USBIP2488-24N-AP)
Leverancier:
US Biological
Omschrijving:
Anti-PAK4 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
UOM:
1 * 200 µl
Itemnummer:
(USBIP2488-27B-APC)
Leverancier:
US Biological
Omschrijving:
Anti-PAK6 Rabbit Polyclonal Antibody (APC (Allophycocyanin))
UOM:
1 * 200 µl
Itemnummer:
(USBIM2868-23B-HRP)
Leverancier:
US Biological
Omschrijving:
Anti-Melanocortin Receptor 3 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
UOM:
1 * 200 µl
Leverancier:
Biotium
Omschrijving:
Recognizes a protein of 27 kDa, identified as the Bcl-X protein. This MAb shows no cross-reaction with Bcl-2 or Bax protein. Bcl-X has two isoforms, Bcl-XL (long), a 241 amino acid protein which suppresses cell death. And Bcl-XS (short), a 178 amino acid protein lacking a 63 amino acid domain which functions as a dominant inhibitor of Bcl-2. This MAb reacts with both Bcl-XS and Bcl-XL proteins.
Leverancier:
Biotium
Omschrijving:
CA19-9, a carbohydrate epitope expressed on a high MW (>400 kDa) mucin glycoprotein, is a sialyl Lewisa structure which is synthesized from type 1 blood group precursor chains and is present in individuals expressing the Lewisa and/or Lewisb blood group antigens. In normal tissues, sialyl Lewisa antigen is present in ductal epithelium of the breast, kidney, salivary gland, and sweat glands. Its expression is greatly enhanced in serum as well as in the majority of tumor cells in gastrointestinal (GI) carcinomas, including adenocarcinomas of the stomach, intestine, and pancreas. Preoperative elevated CA19-9 levels in patients with stage I pancreatic carcinoma decrease to normal values following surgery. When used serially, CA19-9 can predict recurrence of disease prior to radiographic or clinical findings. This MAb is excellent for staining of formalin-fixed, paraffin-embedded tissues.
Itemnummer:
(USBI043348-AP)
Leverancier:
US Biological
Omschrijving:
Anti-TSC2 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
UOM:
1 * 200 µl
Itemnummer:
(USBI037576-APC)
Leverancier:
US Biological
Omschrijving:
Anti-KLKP1 Rabbit Polyclonal Antibody (APC (Allophycocyanin))
UOM:
1 * 200 µl
Itemnummer:
(USBIA0859-90B)
Leverancier:
US Biological
Omschrijving:
Anti-AP2A1 Mouse Monoclonal Antibody [clone: 10K99]
UOM:
1 * 1 EA
Itemnummer:
(USBIA0868-36F)
Leverancier:
US Biological
Omschrijving:
Anti-Adeno-Associated Virus 2, VP1, VP2 Mouse Monoclonal Antibody [clone: 5F149]
UOM:
1 * 50 µG
Itemnummer:
(USBI043563-HRP)
Leverancier:
US Biological
Omschrijving:
Anti-UCHL5 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
UOM:
1 * 200 µl
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 nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11.
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
Dit product is gemarkeerd als beperkt en kan enkel gekocht worden door goedgekeurde verzendingsaccounts. Als u hulp nodig heeft gelieve dan het VWR-Regelgevend Departement te contacteren via regulatory_affairs@vwr.com.
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