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Antilichamen
Itemnummer:
(BOSSBS-11386R-A350)
Leverancier:
Bioss
Omschrijving:
AADACL3 is a 350 amino acid protein that belongs to the 'GDXG' lipolytic enzyme family and participates in hydrolase activity. Existing as two alternatively spliced isoforms, AADACL3 is encoded by a gene that maps to human chromosome 1p36.21. Chromosome 1, the largest human chromosome, makes up 8% of the human genome and contains about 260 million base pairs, which encode 3,000 genes. Chromosome 1 houses a large number of disease-associated genes, including those that are involved in familial adenomatous polyposis, Stickler syndrome, Parkinson’s disease, Gaucher disease, schizophrenia and Usher syndrome. Aberrations in chromosome 1 are found in a variety of cancers, including head and neck cancer, malignant melanoma and multiple myeloma.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-7778R-CY5)
Leverancier:
Bioss
Omschrijving:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-7778R-A680)
Leverancier:
Bioss
Omschrijving:
Component of the anaphase promoting complex/cyclosome (APC/C), a cell cycle-regulated E3 ubiquitin ligase that controls progression through mitosis and the G1 phase of the cell cycle. The APC/C complex acts by mediating ubiquitination and subsequent degradation of target proteins: it mainly mediates the formation of 'Lys-11'-linked polyubiquitin chains and, to a lower extent, the formation of 'Lys-48'- and 'Lys-63'-linked polyubiquitin chains.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-13283R-CY5)
Leverancier:
Bioss
Omschrijving:
GAPVD1 is a 1478 amino acid peripheral membrane protein that acts both as a GTPase-activating protein (GAP) and a guanine nucleotide exchange factor (GEF). GAPVD1 participates in many processes such as insulin receptor internalization, Glut4 trafficking and endocytosis. In addition, depletion of GAPVD1 leads to delayed EGFR degradation by mediating receptor ubiquination through its RGD domain, suggesting that it may be an important mediator of carcinogenesis resulting from Ras protein mutations. There are six isoforms of GAPVD1 that are produced as a result of alternative splicing events.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-5939R-A350)
Leverancier:
Bioss
Omschrijving:
This gene is overexpressed in prostate and breast cancer.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-5939R-A647)
Leverancier:
Bioss
Omschrijving:
This gene is overexpressed in prostate and breast cancer.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-5939R-CY7)
Leverancier:
Bioss
Omschrijving:
This gene is overexpressed in prostate and breast cancer.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-13282R-CY7)
Leverancier:
Bioss
Omschrijving:
May play an important role in regulating the switch between different pathways for energy production during spermiogenesis and in the spermatozoon. Required for sperm motility and male fertility (By similarity).
UOM:
1 * 100 µl
Leverancier:
Biotium
Omschrijving:
This antibody recognizes a 63 kDa protein, which is identified as TOX3. It contains a high mobility group (HMG)-box, which regulates Ca2 -dependent transcription in neurons through interaction with the cAMP-response-element-binding protein (CREB). TOX3 appears to be associated with breast cancer susceptibility and is expressed downstream of a cytoprotective cascade together with CITED1, a transcriptional regulator that does not bind directly to DNA. TOX3 is predominantly expressed in the brain and forms homodimers. TOX3 overexpression protects neuronal cells from cell death caused by endoplasmic reticulum stress or BAX overexpression through the induction of anti-apoptotic transcripts and repression of pro-apoptotic transcripts.
Leverancier:
Biotium
Omschrijving:
Recognizes a 47-55 kDa-tumor suppressor protein, identified as Wilm's Tumor (WT1) protein. The antibody reacts with all isoforms of the full-length WT1 and also identifies WT1 lacking exon 2-encoded amino acids, frequently found in subsets of sporadic Wilm s tumors.WT1, a sporadic and familial pediatric kidney tumor, is genetically heterogeneous. Wilm s tumor is associated with mutations of WT1, a zinc-finger transcription factor that is essential for the development of the metanephric kidney and the urogenital system. The WT1 gene is normally expressed in fetal kidney and mesothelium, and its expression has been suggested as a marker for Wilm s tumor and mesothelioma. WT1 protein has been identified in proliferative mesothelial cells, malignant mesothelioma, ovarian carcinoma, gonadoblastoma, nephroblastoma, and desmoplastic small round cell tumor. Lung adenocarcinomas rarely stain positive with this antibody. WT1 protein expression in mesothelial cells has become a reliable marker for the diagnosis of mesotheliomas.
Itemnummer:
(USBI035310-FITC)
Leverancier:
US Biological
Omschrijving:
Anti-F2RL2 Rabbit Polyclonal Antibody (FITC (Fluorescein Isothiocyanate))
UOM:
1 * 200 µl
Itemnummer:
(USBI042104-PE)
Leverancier:
US Biological
Omschrijving:
Anti-SNTB1 Rabbit Polyclonal Antibody (PE (Phycoerythrin))
UOM:
1 * 200 µl
Itemnummer:
(USBI137741)
Leverancier:
US Biological
Omschrijving:
Anti-CD4 Rat Monoclonal Antibody (FITC (Fluorescein Isothiocyanate)) [clone: 13H150]
UOM:
1 * 1 EA
Itemnummer:
(USBI135921)
Leverancier:
US Biological
Omschrijving:
Anti-BAG1 Mouse Monoclonal Antibody
UOM:
1 * 50 µG
Itemnummer:
(USBI035594-AP)
Leverancier:
US Biological
Omschrijving:
Anti-FCSD2 Rabbit Polyclonal Antibody (AP (Alkaline Phosphatase))
UOM:
1 * 200 µl
Itemnummer:
(USBI041712-HRP)
Leverancier:
US Biological
Omschrijving:
Anti-SHISA3 Rabbit Polyclonal Antibody (HRP (Horseradish Peroxidase))
UOM:
1 * 200 µl
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 nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11.
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
Dit product is gemarkeerd als beperkt en kan enkel gekocht worden door goedgekeurde verzendingsaccounts. Als u hulp nodig heeft gelieve dan het VWR-Regelgevend Departement te contacteren via regulatory_affairs@vwr.com.
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