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Antilichamen
Itemnummer:
(BOSSBS-3598R-HRP)
Leverancier:
Bioss
Omschrijving:
Cytokine receptor that binds to B-lymphocyte chemoattractant (BLC). Involved in B-cell migration into B-cell follicles of spleen and Peyer patches but not into those of mesenteric or peripheral lymph nodes. May have a regulatory function in Burkitt lymphoma (BL) lymphomagenesis and/or B-cell differentiation.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-15306R-CY3)
Leverancier:
Bioss
Omschrijving:
C8orfK29.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-15307R-A488)
Leverancier:
Bioss
Omschrijving:
C9 is a plasma protein synthesised in the liver and monocytes consisting of a single polypeptide chain. C9 is a part of the membrane attack complex (MAC), an important component of the immune system. The MAC forms upon complement system activation by invading pathogenic bacteria and consists of the four major complement proteins: C5b, C6, C7 and C8. These complement proteins bind to the outer surface of the plasma membrane of the invading cell. C9 binds to the membrane associated C5b-8 protein, which leads to the circular polymerisation of 12-18 C9 molecules. These polymerised C9 molecules form a ring structure in the membrane. Molecules can then diffuse freely through this transmembrane channel, causing cell lysis and destruction of the invading bacterial cell.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-15306R-A680)
Leverancier:
Bioss
Omschrijving:
C8orfK29.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-8404R-A647)
Leverancier:
Bioss
Omschrijving:
OGFOD2
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-8404R-CY7)
Leverancier:
Bioss
Omschrijving:
OGFOD2
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-4592R-HRP)
Leverancier:
Bioss
Omschrijving:
Acts as a negative regulator of the proliferation of normal cells by interacting strongly with CDK4 and CDK6. This inhibits their ability to interact with cyclins D and to phosphorylate the retinoblastoma protein.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-8404R-FITC)
Leverancier:
Bioss
Omschrijving:
OGFOD2
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-15567R-FITC)
Leverancier:
Bioss
Omschrijving:
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-10128R-A750)
Leverancier:
Bioss
Omschrijving:
Linker for activation of T cells (LAT) is an integral membrane protein (36 to 38 kD), which plays an important role in linking engagement of the TCR to the biochemical events of T cell activation. LAT antibody stains thymus and peripheral lymphoid tissues such as T cell areas in lymph nodes and spleen. LAT is expressed in T lymphocytes in interstitial spaces, platelets and megakaryocytes. LAT is not expressed in B cells, macrophages, plasma cells, monocytes, epithelial histiocytes and dendritic cells.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-7796R-A555)
Leverancier:
Bioss
Omschrijving:
This gene encodes a kinetochore protein that functions aspart of the minichromosome instability-12 centromere complex. Theencoded protein is required for proper kinetochore assembly andprogression through the cell cycle. Alternative splicing results inmultiple transcript variants. [provided by RefSeq, Feb 2009].
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-3705R-CY7)
Leverancier:
Bioss
Omschrijving:
Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression. In cooperation with mitochondrial PPIF is involved in activating oxidative stress-induced necrosis; the function is largely independent of transcription. Induces the transcription of long intergenic non-coding RNA p21 (lincRNA-p21) and lincRNA-Mkln1. LincRNA-p21 participates in TP53-dependent transcriptional repression leading to apoptosis and seem to have to effect on cell-cycle regulation. Implicated in Notch signaling cross-over. Prevents CDK7 kinase activity when associated to CAK complex in response to DNA damage, thus stopping cell cycle progression. Isoform 2 enhances the transactivation activity of isoform 1 from some but not all TP53-inducible promoters. Isoform 4 suppresses transactivation activity and impairs growth suppression mediated by isoform 1. Isoform 7 inhibits isoform 1-mediated apoptosis.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-6251R-A488)
Leverancier:
Bioss
Omschrijving:
ARK5, a novel AMPK family member, is the tumor cell survival factor activated by Akt and acts as an ATM kinase under the conditions of nutrient starvation. It plays a key role in tumor malignancy downstream of Akt. Its overexpression is associated with tumor invasion and metastasis.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-6251R-FITC)
Leverancier:
Bioss
Omschrijving:
ARK5, a novel AMPK family member, is the tumor cell survival factor activated by Akt and acts as an ATM kinase under the conditions of nutrient starvation. It plays a key role in tumor malignancy downstream of Akt. Its overexpression is associated with tumor invasion and metastasis.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-1616R-HRP)
Leverancier:
Bioss
Omschrijving:
CAP2 is a identified by its similarity to the gene for human adenylyl cyclase-associated protein. The function of the protein encoded by this gene is unknown. However, the protein appears to be able to interact with adenylyl cyclase-associated protein and actin.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-3792R-CY7)
Leverancier:
Bioss
Omschrijving:
Receptor for complement C3Dd, for the Epstein-Barr virus on human B-cells and T-cells and for HNRPU. Participates in B lymphocytes activation.
UOM:
1 * 100 µl
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 nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11.
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
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