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Antilichamen
Itemnummer:
(BOSSBS-5745R-CY5.5)
Leverancier:
Bioss
Omschrijving:
CKS1 protein binds to the catalytic subunit of the cyclin dependent kinases and is essential for their biological function. The CKS1 mRNA is found to be expressed in different patterns through the cell cycle in HeLa cells, which reflects a specialized role for the encoded protein. At least two transcript variants have been identified for this gene, and it appears that only one of them encodes a protein.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-13160R-CY7)
Leverancier:
Bioss
Omschrijving:
Fibulin-1 and Fibulin-2 associate with Fibronectin and other extracellular matrix proteins. In bone marrow, Fibulin-1 and Fibulin-2 bind to Fibronectin in the adherent layer. Fibulin-1 expression is stimulated by estrogen in ovarian cancer cell lines and has been suggested as both an agent of metastasis in ovarian cancer cells and as an indicator for predicting cancer risk or aggressiveness in ovarian carcinomas. The mobility of cancer cells may be inhibited with increasing exposure to Fibulin-1. Fibulin-2 binds to the lectin domains of extracellular matrix proteins aggrecan, versican and brevican. Fibulin-2 is abundantly expressed in heart, placenta and ovarian tissue, where it localizes to basement membranes and connective tissue compartments. In mice, differential Fibulin-2 gene expression correlates with the early phase of diabetic kidneys and glomerulosclerosis. The gene encoding human Fibulin-2 maps to chromosome 3p25.1.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-1315R-A680)
Leverancier:
Bioss
Omschrijving:
Reticulons are associated with the endoplasmic reticulum, and are involved in neuroendocrine secretion or in membrane trafficking in neuroendocrine cells. The reticulon protein is a potent neurite outgrowth inhibitor which may also help block the regeneration of the central nervous system in higher vertebrates. Developmental neurite growth regulatory factor with a role as a negative regulator of axon-axon adhesion and growth, and as a facilitator of neurite branching. Reticulon 4 regulates neurite fasciculation, branching and extension in the developing nervous system. Involved in down-regulation of growth, stabilisation of wiring and restriction of plasticity in the adult CNS. It regulates the radial migration of cortical neurons via an RTN4R-LINGO1 containing receptor complex. May inhibit BACE1 activity and amyloid precursor protein processing.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-15207R-CY5)
Leverancier:
Bioss
Omschrijving:
C5orf48 (chromosome 5 open reading frame 48), also known as FLJ27505, MGC163367 or MGC163369, is a 134 amino acid protein. Encoded by a gene that maps to human chromosome 5q23.2, C5orf48 is linked to Autosomal dominant leukodystrophy (ADLD). Chromosome 5 makes up approximately 6% of the human genome and contains 181 million base pairs, which encode 1,000 genes. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is caused by insertions or deletions within the TCOF1 gene and is also associated with chromosome 5. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-1074R-A555)
Leverancier:
Bioss
Omschrijving:
Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-1074R-A647)
Leverancier:
Bioss
Omschrijving:
Transcription activator that binds to antioxidant response (ARE) elements in the promoter regions of target genes. Important for the coordinated up-regulation of genes in response to oxidative stress. May be involved in the transcriptional activation of genes of the beta-globin cluster by mediating enhancer activity of hypersensitive site 2 of the beta-globin locus control region.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-6982R-CY5)
Leverancier:
Bioss
Omschrijving:
Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-6982R-CY3)
Leverancier:
Bioss
Omschrijving:
Modifies the functions of natural killer cells, monocytes and granulocytes. Inhibits C5a-dependent neutrophil enzyme release and chemotaxis.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-15207R-FITC)
Leverancier:
Bioss
Omschrijving:
C5orf48 (chromosome 5 open reading frame 48), also known as FLJ27505, MGC163367 or MGC163369, is a 134 amino acid protein. Encoded by a gene that maps to human chromosome 5q23.2, C5orf48 is linked to Autosomal dominant leukodystrophy (ADLD). Chromosome 5 makes up approximately 6% of the human genome and contains 181 million base pairs, which encode 1,000 genes. Chromosome 5 is associated with Cockayne syndrome through the ERCC8 gene and familial adenomatous polyposis through the adenomatous polyposis coli (APC) tumor suppressor gene. Treacher Collins syndrome is caused by insertions or deletions within the TCOF1 gene and is also associated with chromosome 5. Deletion of 5q or chromosome 5 altogether is common in therapy-related acute myelogenous leukemias and myelodysplastic syndrome.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-13558R-A647)
Leverancier:
Bioss
Omschrijving:
ZNF93
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-2622R-CY5.5)
Leverancier:
Bioss
Omschrijving:
This is a receptor for interleukin-21.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-11629R-A488)
Leverancier:
Bioss
Omschrijving:
Olfactory receptors are G protein-coupled receptors that localize to the cilia of olfactory sensory neurons where they display affinity for and bind to a variety of odor molecules. The genes encoding olfactory receptors comprise the largest family in the human genome. The binding of olfactory receptor proteins to odor molecules triggers a signal transduction that propagates nerve impulses throughout the body, ultimately leading to transmission of the signal to the brain and the subsequent perception of smell. OR10J3 (olfactory receptor 10J3) is a 329 amino acid protein. The gene encoding OR10J3 maps to human chromosome 1.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-8035R-CY5.5)
Leverancier:
Bioss
Omschrijving:
GABARAPL1 belongs to the MAP1 LC3 family. It increases cell surface expression of kappa type opioid receptor through facilitating anterograde intracellular trafficking of the receptor.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-8037R-A680)
Leverancier:
Bioss
Omschrijving:
May modulate activity of cullin-RING E3 ubiquitin ligase (CRL) complexes (PubMed:21778237). Down-regulates activation of NF-kappa-B.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-11628R-HRP)
Leverancier:
Bioss
Omschrijving:
Odorant receptor (Potential). May be involved in taste perception.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-8037R-CY3)
Leverancier:
Bioss
Omschrijving:
COMMD is a new family of proteins with homology to MURR1, a multifunctional protein that inhibits NFkB. These proteins form multimeric complexes and were identified in a biochemical screen for MURR1-associated factors. The family is defined by the presence of a conserved and unique motif termed the COMM (copper metabolism gene MURR1) domain, which functions as an interface for protein-protein interactions. Down-regulates activation of NF-kappa-B.
UOM:
1 * 100 µl
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 nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11.
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
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