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Antilichamen
Itemnummer:
(BOSSBS-6270R)
Leverancier:
Bioss
Omschrijving:
This gene, a member of the cadherin superfamily, encodes one of the receptor tyrosine kinases, which are cell-surface molecules that transduce signals for cell growth and differentiation. This gene plays a crucial role in neural crest development, and it can undergo oncogenic activation in vivo and in vitro by cytogenetic rearrangement. Mutations in this gene are associated with the disorders multiple endocrine neoplasia, type IIA, multiple endocrine neoplasia, type IIB, Hirschsprung disease, and medullary thyroid carcinoma. Two transcript variants encoding different isoforms have been found for this gene. Additional transcript variants have been described but their biological validity has not been confirmed. [provided by RefSeq, Jul 2008].
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-6257R)
Leverancier:
Bioss
Omschrijving:
Negative regulator of MAP3K1/2 signaling. Converts MAP3K2 from its phosphorylated form to its non-phosphorylated form and inhibits autophosphorylation of MAP3K2.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-7617R)
Leverancier:
Bioss
Omschrijving:
Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate. Inhibitor of p53-induced apoptosis.Tissue specificity: Expressed at a moderately low level in many tissues. Most abundant in kidney, prostate, ovary, intestine, and spleen.
UOM:
1 * 100 µl
Itemnummer:
(BOSSBS-7631R)
Leverancier:
Bioss
Omschrijving:
The substrate transported is not yet known. Induces mitochondrial depolarization.
UOM:
1 * 100 µl
Itemnummer:
(USBI036234-PE)
Leverancier:
US Biological
Omschrijving:
Anti-SLC52A1 Rabbit Polyclonal Antibody (PE (Phycoerythrin))
UOM:
1 * 200 µl
Itemnummer:
(USBI036233-PE)
Leverancier:
US Biological
Omschrijving:
Anti-GPR171 Rabbit Polyclonal Antibody (PE (Phycoerythrin))
UOM:
1 * 200 µl
Itemnummer:
(USBIC2255-11M)
Leverancier:
US Biological
Omschrijving:
Anti-CD4 Mouse Monoclonal Antibody (PE (Phycoerythrin)/Cy7®) [clone: 5K60]
UOM:
1 * 1 EA
Itemnummer:
(USBIC2255-31G)
Leverancier:
US Biological
Omschrijving:
Anti-CD4 Rat Monoclonal Antibody (Cy5®)) [clone: 5K206]
UOM:
1 * 1 EA
Itemnummer:
(USBIC2255-77S)
Leverancier:
US Biological
Omschrijving:
Anti-CD4 Mouse Monoclonal Antibody (FITC (Fluorescein))/PE (Phycoerythrin) [clone: 5F5/5F33]
UOM:
1 * 50 Tests
Itemnummer:
(USBIC2255-31A)
Leverancier:
US Biological
Omschrijving:
Anti-CD4 Rat Monoclonal Antibody [clone: 5K206]
UOM:
1 * 500 µG
Itemnummer:
(USBIC2255-11Y)
Leverancier:
US Biological
Omschrijving:
Anti-CD4 Mouse Monoclonal Antibody (Biotin) [clone: 5K84]
UOM:
1 * 500 µG
Itemnummer:
(USBIC2255-11R)
Leverancier:
US Biological
Omschrijving:
Anti-CD4 Mouse Monoclonal Antibody (Biotin) [clone: 5K79]
UOM:
1 * 500 µG
Leverancier:
Biotium
Omschrijving:
Luteinizing hormone (LH) is a glycoprotein. Each monomeric unit is a sugar-like protein molecule; two of these make the full, functional protein. Its structure is similar to the other glycoproteins, follicle-stimulating hormone (FSH), thyroid-stimulating hormone (TSH), and human chorionic gonadotropin (hCG). The protein dimer contains 2 polypeptide units, labeled alpha and beta subunits that are connected by two bridges. The alpha subunits of LH, FSH, TSH, and hCG are identical, and contain 92 amino acids. The beta subunits vary. LH has a beta subunit of 121 amino acids (LHB) that confers its specific biologic action and is responsible for interaction with the LH receptor. This beta subunit contains the same amino acids in sequence as the beta subunit of hCG and both stimulate the same receptor; however, the hCG beta subunit contains an additional 24 amino acids and the hormones differ in the composition of their sugar moieties.LH is synthesized and secreted by gonadotrophs in the anterior lobe of the pituitary gland. In concert with the other pituitary gonadotropin follicle-stimulating hormone (FSH), it is necessary for proper reproductive function. In the female, an acute rise of LH levels triggers ovulation. In the male, where LH has also been called Interstitial Cell-Stimulating Hormone (ICSH), it stimulates Leydig cell production of testosterone. LH is a useful marker in classification of pituitary tumors and the study of pituitary disease.
Leverancier:
Biotium
Omschrijving:
This MAb is specific to kappa light chain of immunoglobulin and shows no cross-reaction with lambda light chain or any of the five heavy chains. It recognizes human Ig kappa light chains of both secreted and cell surface immunoglobulin. It detects also free kappa light chains. In mammals, the two light chains in an antibody are always identical, with only one type of light chain, kappa or lambda. The ratio of Kappa to Lambda is 70:30. However, with the occurrence of multiple myeloma or other B-cell malignancies this ratio is disturbed. Antibody to the kappa light chain is reportedly useful in the identification of leukemias, plasmacytomas, and certain non-Hodgkin's lymphomas. Demonstration of clonality in lymphoid infiltrates indicates that the infiltrate is malignant.
Itemnummer:
(BNUM0031-50)
Leverancier:
Biotium
Omschrijving:
This MAb recognizes the peptide core of gastric mucin M1 (recently identified as Mucin 5AC). Its epitope is located in the C-terminal cysteine rich part of the peptide core of MUC5AC. The epitope is destroyed by beta-mercaptoethanol but not by periodate treatment. This mucin is present in primary ovarian mucinous cancer but usually absent in colorectal adenocarcinoma, thus showing an expression pattern opposite to MUC2. Together with a panel of antibodies, Anti-MUC5AC may be useful for differential identification of primary mucinous ovarian tumors from colon adenocarcinoma metastatic to the ovary. MUC5AC antibodies may also be useful for identification of intestinal metaplasia as well as in the identification of pancreatic carcinoma and pre-cancerous changes vs. normal pancreas.
UOM:
1 * 50 µl
Leverancier:
US Biological
Omschrijving:
Anti-MutS Rabbit Polyclonal Antibody
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 nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11.
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
Dit product is gemarkeerd als beperkt en kan enkel gekocht worden door goedgekeurde verzendingsaccounts. Als u hulp nodig heeft gelieve dan het VWR-Regelgevend Departement te contacteren via regulatory_affairs@vwr.com.
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