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Eiwitten en peptiden
Leverancier:
SEQENS
Omschrijving:
SEQENS IVD manufactures Bovine Serum Albumin (BSA) derived from plasma, collected from healthy animals of French origin. This product is obtained by 'Heat Shock' method, which ensures higher purity and preserves BSA intrinsic properties.
Leverancier:
SEQENS
Omschrijving:
SEQENS IVD manufactures Bovine Serum Albumin (BSA) derived from plasma, collected from healthy animals of French origin. This product is obtained by 'Heat Shock' method, which ensures higher purity and preserves BSA intrinsic properties.
Itemnummer:
(PRSI4473P)
Leverancier:
ProSci Inc.
Omschrijving:
Slitrk4 peptide is used for blocking the activity of Slitrk4 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI96-410)
Leverancier:
ProSci Inc.
Omschrijving:
Insulin-like growth factor 1 (IGF-1) is also known as somatomedin C, IGF1A, IGFI, sulfation factor, and is a hormone similar in molecular structure to insulin. It plays an important role in childhood growth and continues to have anabolic effects in adults. A synthetic analog of IGF-1, mecasermin is used for the treatment of growth failure. IGF-1 consists of 70 amino acids in a single chain with three intramolecular disulfide bridges. IGF-1 has a molecular weight of 7649 daltons. IGF-1 is produced primarily by the liver as an endocrine hormone as well as in target tissues in a paracrine/autocrine fashion. IGF-1 binds to at least two cell surface receptors: the Insulin-like growth factor 1 receptor, abbreviated as "IGF1R", and the insulin receptor. The IGF-1 receptor seems to be the "physiologic" receptor - it binds IGF-1 at significantly higher affinity than the IGF-1 that is bound to the insulin receptor. Like the insulin receptor, the IGF-1 receptor is a receptor tyrosine kinase - meaning it signals by causing the addition of a phosphate molecule on particular tyrosines. Its primary action is mediated by binding to its specific receptor IGF1R, present on many cell types in many tissues. Binding to the IGF1R, a receptor tyrosine kinase, initiates intracellular signaling; IGF-1 is one of the most potent natural activators of the AKT signaling pathway, a stimulator of cell growth and proliferation, and a potent inhibitor of programmed cell death. Insulin-like growth factor 1 has been shown to bind and interact with all the IGF-1 Binding Proteins (IGFBPs), of which there are six (IGFBP1-6). Specific references are provided for interactions with IGFBP3, IGFBP4 and IGFBP7.
UOM:
1 * 1 EA
Itemnummer:
(PRSI96-477)
Leverancier:
ProSci Inc.
Omschrijving:
Interleukin-6 receptor subunit beta (IL6ST) is also known as IL-6 receptor subunit beta, IL-6R subunit beta, IL-6R-beta, IL-6RB, Interleukin-6 signal transducer, Membrane glycoprotein 130 (gp130), CD130, Oncostatin-M receptor subunit alpha and Il6st,which is single-pass type I membrane protein. IL6ST /gp130 /CD130 can be found in tissues such as brain, heart, thymus, spleen, kidney, lung and liver and found in all the cell lines tested except BaF-B03.The expression of IL-6ST /gp130 is not restricted to IL6-responsive cells. The receptor systems for IL6, LIF, OSM, CNTF, IL11, CTF1 and BSF3 can utilize gp130 for initiating signal transmission. IL6ST /CD130 can bind to IL6 /IL6R (alpha chain) complex, resulting in the formation of high-affinity IL6 binding sites, and transduce the signal. IL6ST /GP130 does not bind IL6 and may have a role in embryonic development.
UOM:
1 * 1 EA
Itemnummer:
(PRSI5563P)
Leverancier:
ProSci Inc.
Omschrijving:
SYNGR1 peptide is used for blocking the activity of SYNGR1 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI5555P)
Leverancier:
ProSci Inc.
Omschrijving:
PRDM16 peptide is used for blocking the activity of PRDM16 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI4685P)
Leverancier:
ProSci Inc.
Omschrijving:
Nanos1 peptide is used for blocking the activity of Nanos1 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI4675P)
Leverancier:
ProSci Inc.
Omschrijving:
BICD2 peptide is used for blocking the activity of BICD2 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI6183P)
Leverancier:
ProSci Inc.
Omschrijving:
VPS39 peptide is used for blocking the activity of VPS39 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI90-149)
Leverancier:
ProSci Inc.
Omschrijving:
CTRP5 (C1qTNF-related protein 5; C1QTNF5) belongs to a highly conserved family of adiponectin paralogs. CTRP5 mediates activation of AMP-activated protein kinase (AMPK) in muscle and liver cells, thereby regulating glucose and lipid metabolism. Serum levels of CTRP5 are significantly higher in obese/diabetic animal models compared to normal controls. Furthermore, CTRP5 may be a putative biomarker for mitochondrial dysfunction. Defects in C1QTNF5 are a cause of late-onset retinal degeneration (LORD).
UOM:
1 * 50 µG
Itemnummer:
(PRSI90-168)
Leverancier:
ProSci Inc.
Omschrijving:
Contactin-6 is a member of the contactins, which mediate cell surface interactions during nervous system development. Contactin-6 has a key role in the formation of glutamatergic, but not GABAergic, synapses during postnatal development of the hippocampal formation as well as the cerebellum. It is involved in oligodendrocytes generation by acting as a ligand of Notch1. It is also involved in motor coordination.
UOM:
1 * 1 EA
Itemnummer:
(PRSI91-751)
Leverancier:
ProSci Inc.
Omschrijving:
Calumenin is a secreted calcium-binding protein that belongs to the CREC family. Calumenin contains six EF-hand domains and is expressed at high levels in the heart, placenta and skeletal muscle. Human Calumenin is synthesized as a 315 amino acid precursor that contains a 19 amino acid signal sequence, and a 296 amino acid mature chain. Calumenin localizes to the endoplasmic reticulum (ER) and sarcoplasmic reticulum (SR) of mammalian tissues which plays a role in ER functions as protein folding and sorting. Calumenin is involved in the regulation of vitamin K-dependent carboxylation of multiple N-terminal glutamate residues. It seems to inhibit gamma -carboxylase GGCX.
UOM:
1 * 50 µG
Itemnummer:
(PRSI4925P)
Leverancier:
ProSci Inc.
Omschrijving:
PTCHD2 peptide is used for blocking the activity of PTCHD2 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI4953P)
Leverancier:
ProSci Inc.
Omschrijving:
NIPSNAP2 peptide is used for blocking the activity of NIPSNAP2 antibody.
UOM:
1 * 50 µG
Itemnummer:
(PRSI4939P)
Leverancier:
ProSci Inc.
Omschrijving:
LASS5 peptide is used for blocking the activity of LASS5 antibody.
UOM:
1 * 50 µG
Bel voor prijs
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 nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11.
De voorraad voor dit item is beperkt, maar kan beschikbaar zijn in een kortbijgelegen magazijn. Gelieve te controleren of u bent aangemeld op de site zodat de beschikbare voorraad weergegeven kan worden. Als het
nog steeds zichtbaar is en u hulp nodig heeft, gelieve VWR te contacteren via 016/38 50 11/
Dit product is gemarkeerd als beperkt en kan enkel gekocht worden door goedgekeurde verzendingsaccounts. Als u hulp nodig heeft gelieve dan het VWR-Regelgevend Departement te contacteren via regulatory_affairs@vwr.com.
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