BMLAK3010001
BMLAK3020001
BMLAK3030001
BMLAK3040001
BMLAK3060001
BMLAK3070001
BMLAK3110001
BMLAK3120001
ENZOBMLAK3010001EA
728.2
EUR
InStock
ENZOBMLAK3010001
ENZOBMLAK3020001
ENZOBMLAK3030001
ENZOBMLAK3040001
ENZOBMLAK3060001
ENZOBMLAK3070001
ENZOBMLAK3110001
ENZOBMLAK3120001
MMP Fluorometric drug discovery kits, RED and GREEN
Testen
Enzyme-assays
The matrix metalloproteinase (MMP) RED and GREEN Drug Discovery Kits are complete assay systems designed to screen MMP inhibitors, using long-wavelength quenched fluorogenic substrates OmniMMP™ RED or Fluorogenic Substrate (GREEN). The assays are performed in a convenient 96-well microplate format, with the compound NNGH also included as a prototypic control inhibitor.
- Improved red-shifted substrate with better kinetics and brighter signal
- Includes active recombinant enzyme, substrate, and assay buffer
- Convenient real-time kinetics of cleavage is easily determined
- Microplate format for high-throughput screening
Proteins of the matrix metalloproproteinase (MMP) family are collectively involved in the breakdown of extracellular matrix proteins and processing of bioactive molecules and are required for some normal processes. Unfortunately, these proteins are also associated with many pathological processes including cirrhosis, arthritis, metastasis, and chronic cardiovascular diseases. Collagenases (MMP-1, MMP-8, and MMP-13) and gelatinases (MMP-2 and MMP-9) also break down skin collagens, contributing to aging and wrinkling.
Leveringsinformatie: Each kit contains 1 vial MMP enzyme, 1 vial substrate, 1 vial calibration standard, 1 vial control inhibitor (NNGH), 1 bottle (20 ml) assay buffer, 1 black 96-well microplate and instructions.