0215284325
0215284301
0215284305
ICNA0215284325EA
460
EUR
InStock
ICNA0215284325
ICNA0215284301
ICNA0215284305
Antipain dihydrochloride, MP Biomedicals
Eiwitten en peptiden
Antipain inhibits trypsin, papain, and catherpsins A and B (a reversible inhibitor of cysteine and serine proteases). It is used to evaluate the role of proteases in cell transformations. It is used to help identify new proteases.
Stability: Working solutions are stable for only a few hours. Stock solutions of 10 mM in water or buffer are stable for 1 week at 4 °C, or 1 month if aliquoted and stored at –20 °C. Dilute a 10 mM stock solution 1:100 to make a 100 µM working solution.
Soluble in water, DMSO or methanol.
Reversible inhibitor of serine/cysteine proteases and some trypsin-like serine proteases. Its action resembles leupeptin; however, its plasmin inhibition is less and its cathepsin A inhibition is more than that observed with leupeptin. Chronic administration can reduce the frequency of chemically induced transformation in BALB/c-/3T3 cells.
Source/Species: Microbial Inhibitor for trypsin, papain, and cathepsins A and B. Ref: 1. Suda, H., et al., J. Antibiot., 25: 263, (1972); 2. Umezawa, H., et al., J. Antibiot., 25: 267, (1972); 3. Ikezawa, H., et al., J. Antibiot., 25: 738, (1972).