0210057025
02100570.5
0210057001
0210057005
ICNA0210057025EA
1247.8
EUR
InStock
ICNA0210057025
ICNA02100570.5
ICNA0210057001
ICNA0210057005
Glycine ≥98%, powder
Glycine
Glycine is a non-essential amino acid. Acts as an inhibitory neurotransmitter, particularly in brain stem and medulla. Shown to block NMDA-stimulated dopamine release in fetal mesencephalic cell cultures. Also reported to increase NMDA-receptor mediated synaptic potential in cortical neurons. It does not have a chiral center, so only amino acid with no asymmetric carbon. Therefore, it does not have a D- or L- isomer designation. This material is synthetic. It is the smallest of the 20 natural amino acids.
Glycine is commonly used as a component in Tris-glycine and Tris-glycine-SDS running buffers for polyacrylamide gel electrophoresis, a component of Towbin's transfer buffer for Western blots, a buffer substance in cryoenzymology, in osmotic pressure maintenance in isoelectric focusing of erythrocytes, salting-in effect in protein chemistry, and as a buffer component in the coupled phosphatase-kinase reaction for end labelling of restriction fragments. The growth requirements of various microorganisms is reported in the Handbook of Microbiology.
It is a non-chiral amino acid that can be synthesised in the body from the amino acid serine by Serine Hydroxy methyltransferase.
Soluble in water (250 mg/ml at 25 °C; 672 mg/ml at 100 °C); slightly soluble in alcohol and ethanol(95%); almost insoluble in ether.
Soluble in water (250 mg/ml at 25 °C; 672 mg/ml at 100 °C); slightly soluble in alcohol and ethanol(95%); almost insoluble in ether.