100-212-5UG
100-212-20UG
100-212-100UG
100-212-500UG
100-212-1UG
SHBT100-212-5UGEA
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SHBT100-212-5UG
SHBT100-212-20UG
SHBT100-212-100UG
SHBT100-212-500UG
SHBT100-212-1UG
Human Recombinant BMP-4 (from CHO cells)
Eiwitten en peptiden
Myostatin, also known as GDF-8, is a conserved member of the TGF-beta superfamily. Myostatin is an essential regulator of skeletal muscle mass and cardiac muscle development and function. Myostatin is a secreted protein that negatively regulates skeletal muscle growth by determining muscle fiber number and size.
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Myostatin binds one of the two activin type II receptors (ACTRIIA or ACTRIIB) to activate SMAD signaling. Myostatin also activates MAPK signaling through TAK1-MKK6 and Ras pathways. Inhibition of myostatin increases muscle mass in a number of human disease animal models, such as muscular dystrophy.
Leveringsinformatie: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
Opgelet: For research use only.