100-16AF-100UG
100-16AF-10UG
100-16AF-1MG
100-16AF-500UG
SHBT100-16AF-100UGEA
561
EUR
InStock
SHBT100-16AF-100UG
SHBT100-16AF-10UG
SHBT100-16AF-1MG
SHBT100-16AF-500UG
Human Recombinant PDGF-AA (Animal free) (from E. coli)
Eiwitten en peptiden
Platelet-derived growth factor (PDGF) is an important regulator of cell growth, proliferation, and angiogenesis. PDGF synthesis is induced by IL-1, IL-6, TNF-α, TGF-β and EGF signaling. PDGF functions as a mitogenic growth hormone on cells of mesenchymal lineage, such as smooth muscle and glial cells.
- High quality
- Low endotoxin
- Affordable
PDGF is also stored in the alpha-granules of platelets and is released upon adherence to traumatized tissues. PDGF is a dimeric glycoprotein formed by two A chains (AA), two B chains (BB), or as a heterodimer with an A and a B chain (AB). The PDGF dimer binds the cell surface receptor tyrosine kinases PDGFR-α and PDGFR-β.
These research grade recombinant proteins are typically used as cytokines, growth factors and chemokines in cell based assays and cell culture.
Leveringsinformatie: A certificate of analysis (COA) is supplied with each product shipped detailing purity, formulation, biological activity, endotoxin levels, reconstitution instructions and recommended storage conditions.
Opgelet: For research use only.