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Ace+Method+Development+Kits
Numéro de catalogue:
(PRSI25-055)
Fournisseur:
ProSci Inc.
Description:
PIT1 is a pituitary-specific transcription factor responsible for pituitary development and hormone expression in mammals and is a member of the POU family of transcription factors that regulate mammalian development. The POU family is so named because the first 3 members identified were PIT1 and OCT1 of mammals, and Unc-86 of C. elegans. PIT1 contains 2 protein domains, termed POU-specific and POU-homeo, which are both necessary for high affinity DNA binding on genes encoding growth hormone and prolactin. PIT1 is also important for regulation of the genes encoding prolactin and thyroid-stimulating hormone beta subunit by thyrotropin-releasing hormone and cyclic AMP. This gene encodes a member of the POU family of transcription factors that regulate mammalian development. The protein regulates expression of several genes involved in pituitary development and hormone expression. Mutations in this genes result in combined pituitary hormone deficiency. Multiple transcript variants encoding different isoforms have been found for this gene.
UOM:
1 * 50 µG
Numéro de catalogue:
(BOSSBS-1531R-A680)
Fournisseur:
Bioss
Description:
Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Cooperates with FOXO1 in osteoblasts to regulate glucose homeostasis through suppression of beta-cell production and decrease in insulin production (By similarity). It binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I. Regulates the induction of DDIT3/CHOP and asparagine synthetase (ASNS) in response to ER stress. In concert with DDIT3/CHOP, activates the transcription of TRIB3 and promotes ER stress-induced neuronal apoptosis by regulating the transcriptional induction of BBC3/PUMA. Activates transcription of SIRT4. Regulates the circadian expression of the core clock component PER2 and the serotonin transporter SLC6A4. Binds in a circadian time-dependent manner to the cAMP response elements (CRE) in the SLC6A4 and PER2 promoters and periodically activates the transcription of these genes.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1531R-A488)
Fournisseur:
Bioss
Description:
Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Cooperates with FOXO1 in osteoblasts to regulate glucose homeostasis through suppression of beta-cell production and decrease in insulin production (By similarity). It binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I. Regulates the induction of DDIT3/CHOP and asparagine synthetase (ASNS) in response to ER stress. In concert with DDIT3/CHOP, activates the transcription of TRIB3 and promotes ER stress-induced neuronal apoptosis by regulating the transcriptional induction of BBC3/PUMA. Activates transcription of SIRT4. Regulates the circadian expression of the core clock component PER2 and the serotonin transporter SLC6A4. Binds in a circadian time-dependent manner to the cAMP response elements (CRE) in the SLC6A4 and PER2 promoters and periodically activates the transcription of these genes.
UOM:
1 * 100 µl
Numéro de catalogue:
(PRSI25-475)
Fournisseur:
ProSci Inc.
Description:
OTX1 probably plays a role in the development of the brain and the sense organs. OTX1 can bind to the BCD target sequence (BTS): 5'-TCTAATCCC-3'.This gene encodes a member of the bicoid sub-family of homeodomain-containing transcription factors. The encoded protein acts as a transcription factor and may play a role in brain and sensory organ development. A similar protein in mice is required for proper brain and sensory organ development and can cause epilepsy.
UOM:
1 * 50 µG
Numéro de catalogue:
(BOSSBS-0052R-A750)
Fournisseur:
Bioss
Description:
Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molecule FADD recruits it to either receptor. The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases. Proteolytic fragments of the N-terminal propeptide (termed CAP3, CAP5 and CAP6) are likely retained in the DISC. Cleaves and activates CASP3, CASP4, CASP6, CASP7, CASP9 and CASP1. May participate in the GZMB apoptotic pathways. Cleaves ADPRT. Hydrolyses the small-molecule substrate, Ac-Asp-Glu-Val-Asp-|-AMC. Likely target for the cowpox virus CRMA death inhibitory protein.
UOM:
1 * 100 µl
Numéro de catalogue:
(PRSI27-805)
Fournisseur:
ProSci Inc.
Description:
ODAG (Ocular development-associated gene), a novel transcription factor located on chromosome 7, encodes a protein that may play a role in eye development. mRNA profiling in multiple human tissue indicates that ODAG is expressed in human CD56+ NK cells and thyroid tissue.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI7087)
Fournisseur:
ProSci Inc.
Description:
LMX1A Antibody: The LIM homeobox transcription factor 1 (LMX1A) belongs to the LIM-homeodomain family. Members of this family are known to be important for pattern formation during development. LMX1A binds an A/T-rich sequence and functions in the nucleus as a transcriptional activator to the insulin gene promoter. In the developing embryo, LMX1A is expressed along the neuraxis and leads to the development of the roof plate of the vertebrae. While LMX1A is crucial for the differentiation of dopamine neurons, the related LMX1B appears to be important for both the development and the survival of these cells. It has been suggested that LMX1A might be a useful biomarker or risk factor in tumor aggressiveness.
UOM:
1 * 1 EA
Numéro de catalogue:
(AATB50627)
Fournisseur:
AAT BIOQUEST INC
Description:
Norfentanyl-Biotin is an excellent probe for developing assays and tests for detecting norfentanyl substances.
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(AATB344)
Fournisseur:
AAT BIOQUEST INC
Description:
5(6)-Carboxyrhodamine 6G ethylenediamine is a building block for developing rhodamine bioconjugates.
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(460-0324)
Fournisseur:
GRANT INSTRUMENTS
Description:
Le TS-DW a été conçu pour l'agitation et le chauffage de plaques à puits profonds. Un principe à multi-systèmes utilisé dans la conception de l'agitateur thermique lui permet de fonctionner comme 3 appareils indépendants : incubateur, agitateur de plaques et agitateur thermique. Pour une utilisation dans les applications des sciences de la vie, en biologie moléculaire, en laboratoire de biologie cellulaire, en lyse cellulaire, en isolation et purification de l'ADN, en préparation d'échantillons pour PCR, en remise en suspension Pellet, ou avec toute autre méthode où de nombreux échantillons doivent être mélangés dans des plaques à puits profonds.
UOM:
1 * 1 ST
Numéro de catalogue:
(BOSSBS-1531R-HRP)
Fournisseur:
Bioss
Description:
Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Cooperates with FOXO1 in osteoblasts to regulate glucose homeostasis through suppression of beta-cell production and decrease in insulin production (By similarity). It binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I. Regulates the induction of DDIT3/CHOP and asparagine synthetase (ASNS) in response to ER stress. In concert with DDIT3/CHOP, activates the transcription of TRIB3 and promotes ER stress-induced neuronal apoptosis by regulating the transcriptional induction of BBC3/PUMA. Activates transcription of SIRT4. Regulates the circadian expression of the core clock component PER2 and the serotonin transporter SLC6A4. Binds in a circadian time-dependent manner to the cAMP response elements (CRE) in the SLC6A4 and PER2 promoters and periodically activates the transcription of these genes.
UOM:
1 * 100 µl
Numéro de catalogue:
(PRSI92-114)
Fournisseur:
ProSci Inc.
Description:
Insulin-Like Growth Factor II (IGF2) belongs to the insulin family of polypeptide growth factors that is involved in development and growth. Members of this family are structurally homologous to proinsulin, and share higher sequence identity. IGF2 is expressed only from the paternally inherited allele and believed to be secreted by the liver and to circulate in the blood. IGF2 possess growth-promoting activity and can stimulate the proliferation and survival of various cell types including muscle, bone, and cartilage tissue in vitro. IGF2 is influenced by placental lactogen and may play a role in fetal development.
UOM:
1 * 50 µG
Fournisseur:
Sampling Systems
Description:
The U-D sleeve sampler was developed for accurate unit dose samples (small volume).
Numéro de catalogue:
(MIEL12506230)
Fournisseur:
MIELE
Description:
Le PG 8504 est une unité sur pied avec couvercle et boîtier extérieur en acier inoxydable. Il relève de nombreux défis en matière de nettoyage dans les environnements de laboratoire. Sa capacité améliorée permet de nettoyer rapidement un grand nombre d'ustensiles et d'équipements.
UOM:
1 * 1 ST
New Product
Fournisseur:
AAT BIOQUEST INC
Description:
AAT Bioquest's iFluor® dyes are developed for labeling proteins, in particular, antibodies.
Numéro de catalogue:
(AATB1154)
Fournisseur:
AAT BIOQUEST INC
Description:
mFluor™ dyes are developed for multicolor flow cytometry-focused applications.
UOM:
1 * 1 mg
New Product
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