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Ace+Method+Development+Kits
Numéro de catalogue:
(PRSI27-956)
Fournisseur:
ProSci Inc.
Description:
Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. However, its exact significance is still obscure.Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure.Alpha2-HS glycoprotein (AHSG), a glycoprotein present in the serum, is synthesized by hepatocytes. The AHSG molecule consists of two polypeptide chains, which are both cleaved from a proprotein encoded from a single mRNA. It is involved in several functions, such as endocytosis, brain development and the formation of bone tissue. The protein is commonly present in the cortical plate of the immature cerebral cortex and bone marrow hemopoietic matrix, and it has therefore been postulated that it participates in the development of the tissues. However, its exact significance is still obscure. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI25-037)
Fournisseur:
ProSci Inc.
Description:
GRHL1 is a member of the grainyhead family of transcription factors. GRHL1 interacts with sister of mammalian grainyhead (SOM) and may function as a transcription factor during development. Two transcript variants encoding distinct isoforms have been identified for GRHL1.This gene encodes a member of the grainyhead family of transcription factors. The encoded protein interacts with sister of mammalian grainyhead (SOM) and may function as a transcription factor during development. Two transcript variants encoding distinct isoforms have been identified for this gene.
UOM:
1 * 50 µG
Numéro de catalogue:
(BOSSBS-0052R-CY3)
Fournisseur:
Bioss
Description:
Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molecule FADD recruits it to either receptor. The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases. Proteolytic fragments of the N-terminal propeptide (termed CAP3, CAP5 and CAP6) are likely retained in the DISC. Cleaves and activates CASP3, CASP4, CASP6, CASP7, CASP9 and CASP1. May participate in the GZMB apoptotic pathways. Cleaves ADPRT. Hydrolyzes the small-molecule substrate, Ac-Asp-Glu-Val-Asp-|-AMC. Likely target for the cowpox virus CRMA death inhibitory protein.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-0052R-FITC)
Fournisseur:
Bioss
Description:
Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molecule FADD recruits it to either receptor. The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases. Proteolytic fragments of the N-terminal propeptide (termed CAP3, CAP5 and CAP6) are likely retained in the DISC. Cleaves and activates CASP3, CASP4, CASP6, CASP7, CASP9 and CASP1. May participate in the GZMB apoptotic pathways. Cleaves ADPRT. Hydrolyzes the small-molecule substrate, Ac-Asp-Glu-Val-Asp-|-AMC. Likely target for the cowpox virus CRMA death inhibitory protein.
UOM:
1 * 100 µl
Numéro de catalogue:
(AATB50026)
Fournisseur:
AAT BIOQUEST INC
Description:
Sulfadimidine-BSA conjugate is used for developing anti-sulfadimidine antibodies that are typically used in an ELISA assay.
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(PRSI79-993)
Fournisseur:
ProSci Inc.
Description:
Tyrosine-protein kinase that acts as cell-surface receptor for fibroblast growth factors and plays an essential role in the regulation of embryonic development, cell proliferation, differentiation and migration. Required for normal mesoderm patterning and correct axial organization during embryonic development, normal skeletogenesis and normal development of the gonadotropin-releasing hormone (GnRH) neuronal system. Phosphorylates PLCG1, FRS2, GAB1 and SHB. Ligand binding leads to the activation of several signaling cascades. Activation of PLCG1 leads to the production of the cellular signaling molecules diacylglycerol and inositol 1,4,5-trisphosphate. Phosphorylation of FRS2 triggers recruitment of GRB2, GAB1, PIK3R1 and SOS1, and mediates activation of RAS, MAPK1/ERK2, MAPK3/ERK1 and the MAP kinase signaling pathway, as well as of the AKT1 signaling pathway. Promotes phosphorylation of SHC1, STAT1 and PTPN11/SHP2. In the nucleus, enhances RPS6KA1 and CREB1 activity and contributes to the regulation of transcription. FGFR1 signaling is down-regulated by IL17RD/SEF, and by FGFR1 ubiquitination, internalization and degradation.
UOM:
1 * 1 EA
Numéro de catalogue:
(PROOCERE-040)
Fournisseur:
LGC Standards PROMOCHEM
Description:
Suitable for the development and validation of new analytical methodologies, for the verification of existing processes and for routine use as either calibration or control materials.
UOM:
1 * 10 Ampul
Numéro de catalogue:
(AATB50011)
Fournisseur:
AAT BIOQUEST INC
Description:
1-Aminohydantoin (AHD)-KLH Conjugate is used for developing anti-1-Aminohydantoin (AHD) antibodies that are typically used in an ELISA assay.
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(PRSI77-101)
Fournisseur:
ProSci Inc.
Description:
The JC12 monoclonal antibody specifically reacts with human Foxp1, a winged helix transcription factor that is expressed in almost all human tissue. In several tumor types, the gene is lost suggesting it plays a tumor suppressive role. It plays an important role in the development of the brain, lungs, thymus, and heart. Foxp1 is also involved in the development of early B cells.
UOM:
1 * 0,025 mg
New Product
Numéro de catalogue:
(PRSI55-104)
Fournisseur:
ProSci Inc.
Description:
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. DNMT3A is a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(AATB39008)
Fournisseur:
AAT BIOQUEST INC
Description:
Trifluoromethyl phenyl diazirine maleimide is an excellent building block to develop photoactive probes by reacting with a thiol-containing biomolecule.
UOM:
1 * 5 mg
New Product
Numéro de catalogue:
(ROCK213-4139)
Fournisseur:
Rockland Immunochemicals
Description:
Anti-Sheep Red Blood Cell Antibody may be used in hemagglutination assays. Anti-SHEEP Red Blood Cell Antibody is used to sensitize erythrocytes and quantitate agglutination. Haemagglutination assay or HA is a method of quantification for viruses or bacteria by hemagglutination. Some viral families and many bacteria have envelope or surface proteins which are able to agglutinate (stick to) human or animal red blood cells (RBC) and bind to N-acetylneuraminic acid. As each of the agglutinating molecule attaches to multiple RBCs, a lattice-structure will form. Normally, a virus dilution (e.g. 2-fold from 1:4 to 1:4096) will be applied to an RBC dilution (e.g. 0.1% to 0.7% in steps of 0.2%) for approx. 30 min, often at 4° C, otherwise viruses with neuraminidase activity will detach the virus from the RBCs. Then the lattice forming parts will be counted and the titer calculated. The titer of a hemagglutination assay is determined by the last viable "lattice" structure found. This is because it is at the point where, if diluted anymore, the amount of Virus particles will be less than that of the RBCs and thus not be able to agglutinate them together.
UOM:
1 * 50 mg
Numéro de catalogue:
(PRSI31-157)
Fournisseur:
ProSci Inc.
Description:
TAL1 is a basic helix-loop-helix transcription factor with a critical role in the development of both blood and endothelium.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI25-466)
Fournisseur:
ProSci Inc.
Description:
FOXI1 belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. FOXI1 may plays an important role in the development of the cochlea and vestibulum, as well as embryogenesis.This gene belongs to the forkhead family of transcription factors which is characterized by a distinct forkhead domain. The specific function of this gene has not yet been determined; however, it is possible that this gene plays an important role in the development of the cochlea and vestibulum, as well as embryogenesis. Mutations in this gene may be associated with the common cavity phenotype. Two transcript variants encoding different isoforms have been found for this gene.
UOM:
1 * 50 µG
Numéro de catalogue:
(TAAGTGG0001)
Fournisseur:
KREGLINGER EUROPE
Description:
Nutrient-rich dehydrated culture media. It contains selected growth factors and nutritional requirements optimised to promote bacterial development.
UOM:
1 * 1 ST
Fournisseur:
AAT BIOQUEST INC
Description:
5-FAM alkyne is an excellent building block for developing fluoresceinated bioconjugates by reacting with an azide group.
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