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Ace+Method+Development+Kits
Numéro de catalogue:
(TAAGTGG0001)
Fournisseur:
KREGLINGER EUROPE
Description:
Nutrient-rich dehydrated culture media. It contains selected growth factors and nutritional requirements optimised to promote bacterial development.
UOM:
1 * 1 ST
Numéro de catalogue:
(PRSI31-245)
Fournisseur:
ProSci Inc.
Description:
TAL1 is a basic helix-loop-helix transcription factor with a critical role in the development of both blood and endothelium.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI29-740)
Fournisseur:
ProSci Inc.
Description:
When FAM107A is transfected into cell lines in which it is not expressed, it suppresses cell growth. It may play a role in tumor development.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI29-449)
Fournisseur:
ProSci Inc.
Description:
In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. DAZAP1 is a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL.In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. This gene encodes a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL. Two isoforms are encoded by transcript variants of this gene.In mammals, the Y chromosome directs the development of the testes and plays an important role in spermatogenesis. A high percentage of infertile men have deletions that map to regions of the Y chromosome. The DAZ (deleted in azoospermia) gene cluster maps to the AZFc region of the Y chromosome and is deleted in many azoospermic and severely oligospermic men. It is thought that the DAZ gene cluster arose from the transposition, amplification, and pruning of the ancestral autosomal gene DAZL also involved in germ cell development and gametogenesis. This gene encodes a RNA-binding protein with two RNP motifs that was originally identified by its interaction with the infertility factors DAZ and DAZL. Two isoforms are encoded by transcript variants of this gene.
UOM:
1 * 1 EA
Numéro de catalogue:
(AATB39008)
Fournisseur:
AAT BIOQUEST INC
Description:
Trifluoromethyl phenyl diazirine maleimide is an excellent building block to develop photoactive probes by reacting with a thiol-containing biomolecule.
UOM:
1 * 5 mg
New Product
Numéro de catalogue:
(PRSI55-655)
Fournisseur:
ProSci Inc.
Description:
Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition. Inhibins appear to oppose the functions of activins.
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(PRSI33-005)
Fournisseur:
ProSci Inc.
Description:
SPIB is a transcription factor in the Ets family. It is found in lymphoid cells and not in monocytes or myeloid cells. SPIB is a regulator of pDC development via its interaction with ID2, E2-2 and BCL2-A1. It promotes E2-2 activity and suppresses Id2 expression to enhance pDC development. It also promotes pDC survival by activation of the antiapoptotic gene BCL2-A1.
UOM:
1 * 1 EA
New Product
Numéro de catalogue:
(BOSSBS-6463R-CY7)
Fournisseur:
Bioss
Description:
Most upstream protease of the activation cascade of caspases responsible for the TNFRSF6/FAS mediated and TNFRSF1A induced cell death. Binding to the adapter molecule FADD recruits it to either receptor. The resulting aggregate called death-inducing signaling complex (DISC) performs CASP8 proteolytic activation. The active dimeric enzyme is then liberated from the DISC and free to activate downstream apoptotic proteases. Proteolytic fragments of the N-terminal propeptide (termed CAP3, CAP5 and CAP6) are likely retained in the DISC. Cleaves and activates CASP3, CASP4, CASP6, CASP7, CASP9 and CASP10. May participate in the GZMB apoptotic pathways. Cleaves ADPRT. Hydrolyzes the small-molecule substrate, Ac-Asp-Glu-Val-Asp-|-AMC. Likely target for the cowpox virus CRMA death inhibitory protein. Isoform 5, isoform 6, isoform 7 and isoform 8 lack the catalytic site and may interfere with the pro-apoptotic activity of the complex.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-1531R-A350)
Fournisseur:
Bioss
Description:
Transcriptional activator. Binds the cAMP response element (CRE) (consensus: 5'-GTGACGT[AC][AG]-3'), a sequence present in many viral and cellular promoters. Cooperates with FOXO1 in osteoblasts to regulate glucose homeostasis through suppression of beta-cell production and decrease in insulin production (By similarity). It binds to a Tax-responsive enhancer element in the long terminal repeat of HTLV-I. Regulates the induction of DDIT3/CHOP and asparagine synthetase (ASNS) in response to ER stress. In concert with DDIT3/CHOP, activates the transcription of TRIB3 and promotes ER stress-induced neuronal apoptosis by regulating the transcriptional induction of BBC3/PUMA. Activates transcription of SIRT4. Regulates the circadian expression of the core clock component PER2 and the serotonin transporter SLC6A4. Binds in a circadian time-dependent manner to the cAMP response elements (CRE) in the SLC6A4 and PER2 promoters and periodically activates the transcription of these genes.
UOM:
1 * 100 µl
Numéro de catalogue:
(PRSI91-954)
Fournisseur:
ProSci Inc.
Description:
RSPO1 is a secreted protein,containing 2 FU(furin-like) repeats and 1 TSP type-1 domain and belonging to the R-spondin family. RSPO1 is required for the early development of gonads, regardless of sex. It has been found in mice only eleven days after fertilization. To induce cell proliferation, it acts synergistically with WNT4. They help stabilize beta catenin, which activates downstream targets. RSPO1 is necessary in female sex development. It augments the WNT/ beta catenin pathway to oppose male sex development. In critical gonadal stages, between six and nine weeks after fertilization, the ovaries upregulate it while the testes downregulate it. RSPO1 can potentially aid in the treatment of mucositis, which is characterized by inflammation of the oral cavity. This unfortunate condition often accompanies chemotherapy and radiation in cancer patients with head and neck tumors.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI27-829)
Fournisseur:
ProSci Inc.
Description:
SOX10 is a member of the SOX (SRY-related HMG-box) family of transcription factors involved in the regulation of embryonic development and in the determination of the cell fate. This protein may act as a transcriptional activator after forming a protein complex with other proteins. It acts as a nucleocytoplasmic shuttle protein and is important for neural crest and peripheral nervous system development. Mutations in this gene are associated with Waardenburg-Shah and Waardenburg-Hirschsprung disease.
UOM:
1 * 50 µG
Numéro de catalogue:
(PRSI56-270)
Fournisseur:
ProSci Inc.
Description:
The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities and are involved in a variety of biological processes including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. The mouse homolog of this gene was found to be preferentially expressed in the inner root sheath of the hair follicle, which suggested a role in hair development. [provided by RefSeq].
UOM:
1 * 400 µl
New Product
Numéro de catalogue:
(AATB21187)
Fournisseur:
AAT BIOQUEST INC
Description:
Protonex™ Red 780 NHS ester is an excellent building block for developing a target-specific conjugate that can be used for monitoring a pH-sensitive biological event.
UOM:
1 * 1 mg
New Product
Numéro de catalogue:
(PRSI28-200)
Fournisseur:
ProSci Inc.
Description:
ZNF22 encodes a protein that is expressed in the epithelial component of the developing tooth organ during early bud and cap stages as well as in osteoblasts of craniofacial bone and the developing tongue.
UOM:
1 * 1 EA
Numéro de catalogue:
(PRSI29-192)
Fournisseur:
ProSci Inc.
Description:
TBX20 is a member of the T-box transcription factor family expressed in the developing heart, eye, ventral neural tube, and limbs, indicating a possible role in regulating development of these tissues.
UOM:
1 * 50 µG
Numéro de catalogue:
(AATB50553)
Fournisseur:
AAT BIOQUEST INC
Description:
Estradiol-KLH conjugate is a convenient building block for developing estradiol antibodies and assays.
UOM:
1 * 1 mg
New Product
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