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PharMed®+BPT+Precision+Pump+Tubing
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PharMed®+BPT+Precision+Pump+Tubing
Numéro de catalogue:
(BOSSBS-7048R-A350)
Fournisseur:
Bioss
Description:
Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signaling or GLUT4 trafficking. Confers resistance to dietary obesity. May act by regulating AKT2, but not AKT1, phosphorylation at the plasma membrane. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of actin structures as well as in endocytosis, having a major impact on ligand-induced EGFR internalization and degradation. Participates in regulation of cortical and submembraneous actin by hydrolyzing PtdIns(3,4,5)P3 thereby regulating membrane ruffling. Regulates cell adhesion and cell spreading. Required for HGF-mediated lamellipodium formation, cell scattering and spreading. Acts as a negative regulator of EPHA2 receptor endocytosis by inhibiting via PI3K-dependent Rac1 activation. Acts as a regulator of neuritogenesis by regulating PtdIns(3,4,5)P3 level and is required to form an initial protrusive pattern, and later, maintain proper neurite outgrowth. Acts as a negative regulator of the FC-gamma-RIIA receptor (FCGR2A). Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. Involved in EGF signaling pathway. Upon stimulation by EGF, it is recruited by EGFR and dephosphorylates PtdIns(3,4,5)P3. Plays a negative role in regulating the PI3K-PKB pathway, possibly by inhibiting PKB activity.
UOM:
1 * 100 µl
Numéro de catalogue:
(BOSSBS-7048R-CY3)
Fournisseur:
Bioss
Description:
Phosphatidylinositol (PtdIns) phosphatase that specifically hydrolyzes the 5-phosphate of phosphatidylinositol-3,4,5-trisphosphate (PtdIns(3,4,5)P3) to produce PtdIns(3,4)P2, thereby negatively regulating the PI3K (phosphoinositide 3-kinase) pathways. Plays a central role in regulation of PI3K-dependent insulin signaling, although the precise molecular mechanisms and signaling pathways remain unclear. While overexpression reduces both insulin-stimulated MAP kinase and Akt activation, its absence does not affect insulin signaling or GLUT4 trafficking. Confers resistance to dietary obesity. May act by regulating AKT2, but not AKT1, phosphorylation at the plasma membrane. Part of a signaling pathway that regulates actin cytoskeleton remodeling. Required for the maintenance and dynamic remodeling of actin structures as well as in endocytosis, having a major impact on ligand-induced EGFR internalization and degradation. Participates in regulation of cortical and submembraneous actin by hydrolyzing PtdIns(3,4,5)P3 thereby regulating membrane ruffling. Regulates cell adhesion and cell spreading. Required for HGF-mediated lamellipodium formation, cell scattering and spreading. Acts as a negative regulator of EPHA2 receptor endocytosis by inhibiting via PI3K-dependent Rac1 activation. Acts as a regulator of neuritogenesis by regulating PtdIns(3,4,5)P3 level and is required to form an initial protrusive pattern, and later, maintain proper neurite outgrowth. Acts as a negative regulator of the FC-gamma-RIIA receptor (FCGR2A). Mediates signaling from the FC-gamma-RIIB receptor (FCGR2B), playing a central role in terminating signal transduction from activating immune/hematopoietic cell receptor systems. Involved in EGF signaling pathway. Upon stimulation by EGF, it is recruited by EGFR and dephosphorylates PtdIns(3,4,5)P3. Plays a negative role in regulating the PI3K-PKB pathway, possibly by inhibiting PKB activity.
UOM:
1 * 100 µl
Numéro de catalogue:
(HEID509-02500-00-0)
Fournisseur:
Heidolph Instruments GmbH & Co.KG
Description:
Quick chuck for Hei-TORQUE Value/Precision 100/200 models
UOM:
1 * 1 ST
Numéro de catalogue:
(WILMLG-10800-100)
Fournisseur:
SP Industries
Description:
Tube incorporates a grease-free high vacuum 0 to 4 mm valve and is suited for pressure/vacuum applications. Ideal for reaction and storage of air-sensitive compounds. Sidearm can be connected to inert atmosphere/vacuum source or a manifold.
UOM:
1 * 1 ST
Fournisseur:
BOCHEM
Description:
Precision forceps made from PTFE coated stainless steel.
Fournisseur:
Brand
Description:
Volume fixe, réglage analogique ou Digital Easy Calibration.
Fournisseur:
SP Industries
Description:
Tube RMN
Numéro de catalogue:
(PRSI25-949)
Fournisseur:
ProSci Inc.
Description:
ATP4B belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H (+) and K (+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes the beta subunit of the gastric H+, K+-ATPase.The protein encoded by this gene belongs to a family of P-type cation-transporting ATPases. The gastric H+, K+-ATPase is a heterodimer consisting of a high molecular weight catalytic alpha subunit and a smaller but heavily glycosylated beta subunit. This enzyme is a proton pump that catalyzes the hydrolysis of ATP coupled with the exchange of H (+) and K (+) ions across the plasma membrane. It is also responsible for gastric acid secretion. This gene encodes the beta subunit of the gastric H+, K+-ATPase. Publication Note: This RefSeq record includes a subset of the publications that are available for this gene. Please see the Entrez Gene record to access additional publications.
UOM:
1 * 50 µG
Fournisseur:
VWR Collection
Description:
PP.
Fournisseur:
OHAUS
Description:
The PR series of balances has been designed for routine weighing applications in the workplace.
Fournisseur:
ELGA LabWater
Description:
These systems are designed to deliver compliant purified water at the point of use for a wide range of washer disinfectors and autoclaves to minimise contamination risk to patients.
Numéro de catalogue:
(WILM724-SQ-100M)
Fournisseur:
SP Industries
Description:
Tubes made of synthetic material suppress major impurities during EPR.
UOM:
1 * 1 ST
Fournisseur:
Saint Gobain Life Sciences
Description:
Silicone platine, transparent.
Numéro de catalogue:
(228-4321)
Fournisseur:
Saint Gobain Life Sciences
Description:
En fluoroélastomère (Viton), noir.
UOM:
1 * 1 m
Numéro de catalogue:
(634-6041)
Fournisseur:
VWR Collection
Description:
Spectrophotomètre UV/Vis double faisceau compatible avec de nombreuses applications, notamment pour les laboratoires pharmaceutiques, biochimiques, cliniques et de recherche générale, le développement de nouveaux matériaux et le contrôle qualité.
UOM:
1 * 1 ST
Fournisseur:
Ludwig Schneider GmbH & CO. KG
Description:
Hydromètres de précision (avec ou sans thermomètre) calibrés à une température de 15 °C.
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est toujours affiché et vous avez besoin d'aide, s'il vous plaît appelez-nous au 016 385 011
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